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業績報告ご協力のお願い(2022年度)

 iSAL支援の成果を把握するため、利用者の皆様には研究業績の収集にご協力をお願いします。

 2022年度中またはそれ以前にiSAL支援を活用して得られた結果を含めて発表した各種業績について、①Googleフォームから個別に回答するか、または②EXCELファイルにまとめてメールで提出するをお願いします。

 皆様から頂いた情報をもとに論文掲載数や学会発表数などを集計し、iSAL運営に関連する予算プロジェクトの申請書・報告書等に活用させていただきます。またお寄せいただいた業績報告のうち、学術論文に掲載されたものについては、追って本ページに掲載いたします。

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 ○ 学術論文掲載
 ○ 学会発表
 ○ 上記以外の業績(特許出願など)

②業績報告書(EXCELファイル)

 下記様式(EXCELファイル)をダウンロードして必要事項を入力し、下記提出先にお送りください。研究室単位で回答いただいても個人単位で回答いただいても結構です。

 ○ 学術論文掲載
 ○ 学会発表
 ○ 上記以外の業績(特許出願など)

 ◎ 提出先 : mrsc_and_isal_office[@]mail2.adm.kyoto-u.ac.jp
   ※アットマークのカッコを外し、半角英数に直してご使用下さい。

回答期間

 2023年3月31日(金)まで

Q & A

 Q1. 1つの発表に2名以上の利用者が含まれますがどのように回答したらよいでしょうか。
 A1. 「利用者氏名」の欄に発表に関係する利用者全員の氏名を入力してください。

 Q2. 2021年度までの関連する業績を報告する必要はありますか。
 A2. 過去に各支援担当にご連絡いただいた業績はiSAL内で共有しますので改めて報告いただく必要はありません。未報告の場合はぜひご協力をお願いします。

 Q3. 以前業績報告をしたかどうか定かではありませんが、重複することになっても報告して良いでしょうか。
 A3. はい、問題ありません。過去の記録と照らし合わせ、重複している場合はこちらで削除します。

 Q4. 機密事項など外部に開示できないものについて報告する必要はありますか。
 A4. いいえ、ありません。学術論文掲載など公に発表したものだけで結構です。

利用者業績一覧

2022
Someya Y, Iima M, Imai H, Yoshizawa A, Kataoka M, Isoda H, Le Bihan D, Nakamoto Y.
Investigation of breast cancer microstructure and microvasculature from time-dependent DWI and CEST in correlation with histological biomarkers
Sci Rep. 2022 Apr 20;12(1):6523. doi: 10.1038/s41598-022-10081-7.
Chong YK, Tartey S, Yoshikawa Y, Imami K, Li S, Yoshinaga M, Hirabayashi A, Liu G, Vandenbon A, Hia F, Uehata T, Mino T, Suzuki Y, Noda T, Ferrandon D, Standley DM, Ishihama Y, Takeuchi O.
Cyclin J-CDK complexes limit innate immune responses by reducing proinflammatory changes in macrophage metabolism
Sci Signal. 2022 Apr 12;15(729):eabm5011. doi: 10.1126/scisignal.abm5011. Epub 2022 Apr 12.
Kumagai K, Shimizu T, Takai A, Kakiuchi N, Takeuchi Y, Hirano T, Takeda H, Mizuguchi A, Teramura M, Ito T, Iguchi E, Nikaido M, Eso Y, Takahashi K, Ueda Y, Miyamoto S, Obama K, Ogawa S, Marusawa H, Seno H.
Expansion of Gastric Intestinal Metaplasia with Copy Number Aberrations Contributes to Field Cancerization
Cancer Res. 2022 May 3;82(9):1712-1723. doi: 10.1158/0008-5472.CAN-21-1523.
Kuno S, Fujita H, Tanaka YK, Ogra Y, Iwai K.
Iron-induced NCOA4 condensation regulates ferritin fate and iron homeostasis
EMBO Rep. 2022 May 4;23(5):e54278. doi: 10.15252/embr.202154278. Epub 2022 Mar 23.
Liu W, Ota M, Tabushi M, Takahashi Y, Takakura Y.
Development of allergic rhinitis immunotherapy using antigen-loaded small extracellular vesicles
J Control Release. 2022 May;345:433-442. doi: 10.1016/j.jconrel.2022.03.016. Epub 2022 Mar 14.
Fujita-Fujiharu Y, Sugita Y, Takamatsu Y, Houri K, Igarashi M, Muramoto Y, Nakano M, Tsunoda Y, Taniguchi I, Becker S, Noda T.
Structural insight into Marburg virus nucleoprotein-RNA complex formation
Nat Commun. 2022 Mar 4;13(1):1191. doi: 10.1038/s41467-022-28802-x.
Higashi Y, Ikeda S, Matsumoto K, Satoh S, Komatsu A, Sugiyama H, Tamanoi F.
Tumor Accumulation of PIP-Based KRAS Inhibitor KR12 Evaluated by the Use of a Simple, Versatile Chicken Egg Tumor Model
Cancers (Basel). 2022 Feb 14;14(4):951. doi: 10.3390/cancers14040951.
Hirota K, Ooka M, Shimizu N, Yamada K, Tsuda M, Ibrahim MA, Yamada S, Sasanuma H, Masutani M, Takeda S.
XRCC1 counteracts poly(ADP ribose)polymerase (PARP) poisons, olaparib and talazoparib, and a clinical alkylating agent, temozolomide, by promoting the removal of trapped PARP1 from broken DNA
Genes Cells. 2022 May;27(5):331-344. doi: 10.1111/gtc.12929. Epub 2022 Mar 1.
Matsuoka R, Fudim R, Jung S, Zhang C, Bazzone A, Chatzikyriakidou Y, Robinson CV, Nomura N, Iwata S, Landreh M, Orellana L, Beckstein O, Drew D.
Structure, mechanism and lipid-mediated remodeling of the mammalian Na(+)/H(+) exchanger NHA2
Nat Struct Mol Biol. 2022 Feb;29(2):108-120. doi: 10.1038/s41594-022-00738-2. Epub 2022 Feb 16.
Kishi KE, Kim YS, Fukuda M, Inoue M, Kusakizako T, Wang PY, Ramakrishnan C, Byrne EFX, Thadhani E, Paggi JM, Matsui TE, Yamashita K, Nagata T, Konno M, Quirin S, Lo M, Benster T, Uemura T, Liu K, Shibata M, Nomura N, Iwata S, Nureki O, Dror RO, Inoue K, Deisseroth K, Kato HE.
Structural basis for channel conduction in the pump-like channelrhodopsin ChRmine
Cell. 2022 Feb 17;185(4):672-689.e23. doi: 10.1016/j.cell.2022.01.007. Epub 2022 Feb 2.
Inuki S, Tabuchi H, Matsuzaki C, Yonejima Y, Hisa K, Kimura I, Yamamoto K, Ohno H.
Chemical Synthesis and Evaluation of Exopolysaccharide Fragments Produced by Leuconostoc mesenteroides Strain NTM048
Chem Pharm Bull (Tokyo). 2022;70(2):155-161. doi: 10.1248/cpb.c21-00919.
Tada T, Ohnishi H, Yamamoto N, Kuwata F, Hayashi Y, Okuyama H, Morino T, Kasai Y, Kojima H, Omori K.
Transplantation of a human induced pluripotent stem cell-derived airway epithelial cell sheet into the middle ear of rats
Regen Ther. 2022 Jan 14;19:77-87. doi: 10.1016/j.reth.2022.01.001. eCollection 2022 Mar.
Mukai Y, Horie M, Kojima S, Kawasaki J, Maeda K, Tomonaga K.
An endogenous bornavirus-like nucleoprotein in miniopterid bats retains the RNA-binding properties of the original viral protein
FEBS Lett. 2022 Feb;596(3):323-337. doi: 10.1002/1873-3468.14290. Epub 2022 Jan 30.
Takada N, Takasugi M, Nonaka Y, Kamiya T, Takemura K, Satoh J, Ito S, Fujimoto K, Uematsu S, Yoshida K, Morita T, Nakamura H, Uezumi A, Ohtani N.
Galectin-3 promotes the adipogenic differentiation of PDGFRα+ cells and ectopic fat formation in regenerating muscle
Development. 2022 Feb 1;149(3):dev199443. doi: 10.1242/dev.199443. Epub 2022 Feb 3.
Qiu H, Tsurumi Y, Katoh Y, Nakayama K.
Combinations of deletion and missense variations of the dynein-2 DYNC2LI1 subunit found in skeletal ciliopathies cause ciliary defects
Sci Rep. 2022 Jan 7;12(1):31. doi: 10.1038/s41598-021-03950-0.
Nanjo T, Matsugasako T, Maruo Y, Takemoto Y.
Photocatalytic C-O Bond Cleavage of Alcohols Using Xanthate Salts
Org Lett. 2022 Jan 14;24(1):359-363. doi: 10.1021/acs.orglett.1c04029. Epub 2021 Dec 27.
Zhou Z, Qiu H, Castro-Araya RF, Takei R, Nakayama K, Katoh Y.
Impaired cooperation between IFT74/BBS22-IFT81 and IFT25-IFT27/BBS19 causes Bardet-Biedl syndrome
Hum Mol Genet. 2022 May 19;31(10):1681-1693. doi: 10.1093/hmg/ddab354.
Kawamoto Y, Liu W, Yum JH, Park S, Sugiyama H, Takahashi Y, Takakura Y.
Enhanced Immunostimulatory Activity of Covalent DNA Dendrons
Chembiochem. 2022 Feb 16;23(4):e202100583. doi: 10.1002/cbic.202100583. Epub 2021 Dec 23.
Ito K, Kariya M, Yasui K, Takahashi Y, Takakura Y.
Development of Hydrophobic Interaction-based DNA Supramolecules as Efficient Delivery Carriers of CpG DNA to Immune cells
J Pharm Sci. 2022 Apr;111(4):1133-1141. doi: 10.1016/j.xphs.2021.11.027. Epub 2021 Dec 4.
Lin HH, Horie M, Tomonaga K.
A comprehensive profiling of innate immune responses in Eptesicus bat cells
Microbiol Immunol. 2022 Mar;66(3):97-112. doi: 10.1111/1348-0421.12952. Epub 2022 Jan 31.
Kuwata F, Ohnishi H, Yamamoto N, Takezawa T, Yamashita M, Okuyama H, Hayashi Y, Yoshimatsu M, Kitada Y, Tada T, Kobayashi M, Omori K.
Transplantation of Human Induced Pluripotent Stem Cell-Derived Airway Cells on Vitrigel Membrane into Rat Nasal Cavity
Tissue Eng Part A. 2022 Mar 30. doi: 10.1089/ten.TEA.2021.0071. Online ahead of print.
Sato Y, Oguchi A, Fukushima Y, Masuda K, Toriu N, Taniguchi K, Yoshikawa T, Cui X, Kondo M, Hosoi T, Komidori S, Shimizu Y, Fujita H, Jiang L, Kong Y, Yamanashi T, Seita J, Yamamoto T, Toyokuni S, Hamazaki Y, Hattori M, Yoshikai Y, Boor P, Floege J, Kawamoto H, Murakawa Y, Minato N, Yanagita M.
CD153/CD30 signaling promotes age-dependent tertiary lymphoid tissue expansion and kidney injury
J Clin Invest. 2022 Jan 18;132(2):e146071. doi: 10.1172/JCI146071.
Taichi Yumura, Dr. Takeshi Nanjo, Prof. Dr. Yoshiji Takemoto
Boronic Acid-Mediated Photocatalysis Enables the Intramolecular Hydroacylation of Olefins Using Carboxylic Acids
Eur. J. Org. Chem. 2022 Mar 23 doi:10.1002/ejoc.202200082
Ahmad Luqman-Fatah, Yuzo Watanabe, Fuyuki Ishikawa, John V. Moran, Tomoichiro Miyoshi
The interferon stimulated gene-encoded protein HELZ2 1 inhibits human LINE-1 retrotransposition and LINE-1 RNA-mediated type I interferon induction
bioRxiv 2022 Mar 27 doi:10.1101/2022.03.26.485892
Yousuke Yamaoka, Takuro Yamakawa, Kaito Tateishi, Kiyosei Takasu
Total Synthesis of Cryptopleurine and its Analogues
Synthesis 2022; 54(10): 2415-2422 doiI: 10.1055/a-1730-8628
藤田 陽子
フィロウイルスの粒子構造を視る
週刊医学のあゆみ, vol.280, No. 9, p933-937, 2022
2021
Suezawa T, Kanagaki S, Moriguchi K, Masui A, Nakao K, Toyomoto M, Tamai K, Mikawa R, Hirai T, Murakami K, Hagiwara M, Gotoh S.
Disease modeling of pulmonary fibrosis using human pluripotent stem cell-derived alveolar organoids
Stem Cell Reports. 2021 Dec 14;16(12):2973-2987. doi: 10.1016/j.stemcr.2021.10.015. Epub 2021 Nov 18.
Suezawa T, Kanagaki S, Korogi Y, Nakao K, Hirai T, Murakami K, Hagiwara M, Gotoh S.
Modeling of lung phenotype of Hermansky-Pudlak syndrome type I using patient-specific iPSCs
Respir Res. 2021 Nov 4;22(1):284. doi: 10.1186/s12931-021-01877-8.
Tawatari T, Takasu K, Takikawa H.
2-(Chlorodiisopropylsilyl)-6-(trimethylsilyl)phenyl triflate: a modified platform for intramolecular benzyne cycloadditions
Chem Commun (Camb). 2021 Nov 9;57(89):11863-11866. doi: 10.1039/d1cc05264k.
Komatsu A, Matsumoto K, Yoshimatsu Y, Sin Y, Kubota A, Saito T, Mizumoto A, Ohashi S, Muto M, Noguchi R, Kondo T, Tamanoi F.
The CAM Model for CIC-DUX4 Sarcoma and Its Potential Use for Precision Medicine
Cells. 2021 Oct 1;10(10):2613. doi: 10.3390/cells10102613.
Noguchi T, Nakamura K, Satoda Y, Katoh Y, Nakayama K.
CCRK/CDK20 regulates ciliary retrograde protein trafficking via interacting with BROMI/TBC1D32
PLoS One. 2021 Oct 8;16(10):e0258497. doi: 10.1371/journal.pone.0258497. eCollection 2021.
Komatsu H, Ikeuchi T, Tsuno H, Arichi N, Yasui K, Oishi S, Inuki S, Fukazawa A, Ohno H.
Construction of Tricyclic Nitrogen Heterocycles by a Gold(I)-Catalyzed Cascade Cyclization of Allenynes and Application to Polycyclic π-Electron Systems
Angew Chem Int Ed Engl. 2021 Dec 20;60(52):27019-27025. doi: 10.1002/anie.202111267. Epub 2021 Nov 22.
Takenaga T, Zhang Z, Muramoto Y, Fehling SK, Hirabayashi A, Takamatsu Y, Kajikawa J, Miyamoto S, Nakano M, Urata S, Groseth A, Strecker T, Noda T.
CP100356 Hydrochloride, a P-Glycoprotein Inhibitor, Inhibits Lassa Virus Entry: Implication of a Candidate Pan-Mammarenavirus Entry Inhibitor
Viruses. 2021 Sep 3;13(9):1763. doi: 10.3390/v13091763.
Murakami S, Nanjo T, Takemoto Y.
Photocatalytic Activation of Elemental Sulfur Enables a Chemoselective Three-Component Thioesterification
Org Lett. 2021 Oct 1;23(19):7650-7655. doi: 10.1021/acs.orglett.1c02904. Epub 2021 Sep 16.
Ghilarov D, Inaba-Inoue S, Stepien P, Qu F, Michalczyk E, Pakosz Z, Nomura N, Ogasawara S, Walker GC, Rebuffat S, Iwata S, Heddle JG, Beis K.
Molecular mechanism of SbmA, a promiscuous transporter exploited by antimicrobial peptides
Sci Adv. 2021 Sep 10;7(37):eabj5363. doi: 10.1126/sciadv.abj5363. Epub 2021 Sep 8.
Kinouchi H, Sugimoto K, Yamaoka Y, Takikawa H, Takasu K.
Oxidative β-Cleavage of Fused Cyclobutanols Leading to Hydrofuran-Fused Polycyclic Aromatic Compounds
J Org Chem. 2021 Sep 17;86(18):12615-12622. doi: 10.1021/acs.joc.1c01108. Epub 2021 Sep 2.
Fujisawa S, Qiu H, Nozaki S, Chiba S, Katoh Y, Nakayama K.
ARL3 and ARL13B GTPases participate in distinct steps of INPP5E targeting to the ciliary membrane
Biol Open. 2021 Sep 15;10(9):bio058843. doi: 10.1242/bio.058843. Epub 2021 Sep 28.
Yoshinari Y, Kosakamoto H, Kamiyama T, Hoshino R, Matsuoka R, Kondo S, Tanimoto H, Nakamura A, Obata F, Niwa R.
The sugar-responsive enteroendocrine neuropeptide F regulates lipid metabolism through glucagon-like and insulin-like hormones in Drosophila melanogaster
Nat Commun. 2021 Aug 10;12(1):4818. doi: 10.1038/s41467-021-25146-w.
Neville SL, Sjöhamn J, Watts JA, MacDermott-Opeskin H, Fairweather SJ, Ganio K, Carey Hulyer A, McGrath AP, Hayes AJ, Malcolm TR, Davies MR, Nomura N, Iwata S, O’Mara ML, Maher MJ, McDevitt CA.
The structural basis of bacterial manganese import
Sci Adv. 2021 Aug 6;7(32):eabg3980. doi: 10.1126/sciadv.abg3980. Print 2021 Aug.
Okamoto HH, Miyauchi H, Inoue A, Raimondi F, Tsujimoto H, Kusakizako T, Shihoya W, Yamashita K, Suno R, Nomura N, Kobayashi T, Iwata S, Nishizawa T, Nureki O.
Cryo-EM structure of the human MT(1)-G(i) signaling complex
Nat Struct Mol Biol. 2021 Aug;28(8):694-701. doi: 10.1038/s41594-021-00634-1. Epub 2021 Aug 5.
Iwai S, Ikeda HO, Mera H, Nishitani K, Saito M, Tsujikawa A, Kakizuka A.
KUS121 attenuates the progression of monosodium iodoacetate-induced osteoarthritis in rats
Sci Rep. 2021 Aug 2;11(1):15651. doi: 10.1038/s41598-021-95173-6.
Garcia BCB, Horie M, Kojima S, Makino A, Tomonaga K.
BUD23-TRMT112 interacts with the L protein of Borna disease virus and mediates the chromosomal tethering of viral ribonucleoproteins
Microbiol Immunol. 2021 Nov;65(11):492-504. doi: 10.1111/1348-0421.12934. Epub 2021 Sep 17.
Uehata T, Takeuchi O.
Post-transcriptional regulation of immunological responses by Regnase-1-related RNases
Int Immunol. 2021 Nov 25;33(12):859-865. doi: 10.1093/intimm/dxab048.
Ajiro M, Awaya T, Kim YJ, Iida K, Denawa M, Tanaka N, Kurosawa R, Matsushima S, Shibata S, Sakamoto T, Studer L, Krainer AR, Hagiwara M.
Therapeutic manipulation of IKBKAP mis-splicing with a small molecule to cure familial dysautonomia
Nat Commun. 2021 Jul 23;12(1):4507. doi: 10.1038/s41467-021-24705-5.
Nakano M, Sugita Y, Kodera N, Miyamoto S, Muramoto Y, Wolf M, Noda T.
Ultrastructure of influenza virus ribonucleoprotein complexes during viral RNA synthesis
Commun Biol. 2021 Jul 9;4(1):858. doi: 10.1038/s42003-021-02388-4.
Miyata Y, Nishida E.
Protein quality control of DYRK family protein kinases by the Hsp90-Cdc37 molecular chaperone
Biochim Biophys Acta Mol Cell Res. 2021 Sep;1868(10):119081. doi: 10.1016/j.bbamcr.2021.119081. Epub 2021 Jun 18.
Greiner LC, Inuki S, Arichi N, Oishi S, Suzuki R, Iwai T, Sawamura M, Hashmi ASK, Ohno H.
Access to Indole-Fused Benzannulated Medium-Sized Rings through a Gold(I)-Catalyzed Cascade Cyclization of Azido-Alkynes
Chemistry. 2021 Sep 9;27(51):12992-12997. doi: 10.1002/chem.202101824. Epub 2021 Jul 9.
Maeda S, Shiimura Y, Asada H, Hirata K, Luo F, Nango E, Tanaka N, Toyomoto M, Inoue A, Aoki J, Iwata S, Hagiwara M.
Endogenous agonist-bound S1PR3 structure reveals determinants of G protein-subtype bias
Sci Adv. 2021 Jun 9;7(24):eabf5325. doi: 10.1126/sciadv.abf5325. Print 2021 Jun.
Fujino K, Horie M, Kojima S, Shimizu S, Nabekura A, Kobayashi H, Makino A, Honda T, Tomonaga K.
A Human Endogenous Bornavirus-Like Nucleoprotein Encodes a Mitochondrial Protein Associated with Cell Viability
J Virol. 2021 Jun 24;95(14):e0203020. doi: 10.1128/JVI.02030-20. Epub 2021 Jun 24.
Inoue M, Enomoto M, Yoshimura M, Mizowaki T.
Pharmacological inhibition of sodium-calcium exchange activates NADPH oxidase and induces infection-independent NETotic cell death
Redox Biol. 2021 Jul;43:101983. doi: 10.1016/j.redox.2021.101983. Epub 2021 Apr 26.
Jin F, Sun M, Fujii T, Yamada Y, Wang J, Maturana AD, Wada M, Su S, Ma J, Takeda H, Kusakizako T, Tomita A, Nakada-Nakura Y, Liu K, Uemura T, Nomura Y, Nomura N, Ito K, Nureki O, Namba K, Iwata S, Yu Y, Hattori M.
The structure of MgtE in the absence of magnesium provides new insights into channel gating
PLoS Biol. 2021 Apr 27;19(4):e3001231. doi: 10.1371/journal.pbio.3001231. eCollection 2021 Apr.
Egawa G, Egawa K, Kabashima K.
Is breakthrough chickenpox caused by different genotypes of Varicella zoster virus?
Pediatr Int. 2021 Apr;63(4):478-480. doi: 10.1111/ped.14440. Epub 2021 Apr 3.
Tagawa M, Ikeda HO, Inoue Y, Iwai S, Iida Y, Hata M, Asaka I, Tsujikawa A.
Deterioration of phagocytosis in induced pluripotent stem cell-derived retinal pigment epithelial cells established from patients with retinitis pigmentosa carrying Mer tyrosine kinase mutations
Exp Eye Res. 2021 Apr;205:108503. doi: 10.1016/j.exer.2021.108503. Epub 2021 Feb 17.
Yoshimatsu M, Ohnishi H, Zhao C, Hayashi Y, Kuwata F, Kaba S, Okuyama H, Kawai Y, Hiwatashi N, Kishimoto Y, Sakamoto T, Ikeya M, Omori K.
In vivo regeneration of rat laryngeal cartilage with mesenchymal stem cells derived from human induced pluripotent stem cells via neural crest cells
Stem Cell Res. 2021 Apr;52:102233. doi: 10.1016/j.scr.2021.102233. Epub 2021 Feb 11.
Toyomoto M, Inoue A, Iida K, Denawa M, Kii I, Ngako Kadji FM, Kishi T, Im D, Shimamura T, Onogi H, Yoshida S, Iwata S, Aoki J, Hosoya T, Hagiwara M.
S1PR3-G(12)-biased agonist ALESIA targets cancer metabolism and promotes glucose starvation
Cell Chem Biol. 2021 Aug 19;28(8):1132-1144.e9. doi: 10.1016/j.chembiol.2021.01.004. Epub 2021 Feb 8.
Moribe F, Nishikori M, Takashima T, Taniyama D, Onishi N, Arima H, Sasanuma H, Akagawa R, Elloumi F, Takeda S, Pommier Y, Morii E, Takaori-Kondo A, Murai J.
Epigenetic suppression of SLFN11 in germinal center B-cells during B-cell development
PLoS One. 2021 Jan 29;16(1):e0237554. doi: 10.1371/journal.pone.0237554. eCollection 2021.
Mu A, Hira A, Niwa A, Osawa M, Yoshida K, Mori M, Okamoto Y, Inoue K, Kondo K, Kanemaki MT, Matsuda T, Ito E, Kojima S, Nakahata T, Ogawa S, Tanaka K, Matsuo K, Saito MK, Takata M.
Analysis of disease model iPSCs derived from patients with a novel Fanconi anemia-like IBMFS ADH5/ALDH2 deficiency
Blood. 2021 Apr 15;137(15):2021-2032. doi: 10.1182/blood.2020009111.
Mu A, Hira A, Niwa A, Osawa M, Yoshida K, Mori M, Okamoto Y, Inoue K, Kondo K, Kanemaki MT, Matsuda T, Ito E, Kojima S, Nakahata T, Ogawa S, Tanaka K, Matsuo K, Saito MK, Takata M.
Analysis of disease model iPSCs derived from patients with a novel Fanconi anemia-like IBMFS ADH5/ALDH2 deficiency
Blood. 2021 Apr 15;137(15):2021-2032. doi: 10.1182/blood.2020009111.
Kanagaki S, Suezawa T, Moriguchi K, Nakao K, Toyomoto M, Yamamoto Y, Murakami K, Hagiwara M, Gotoh S.
Hydroxypropyl Cyclodextrin Improves Amiodarone-induced Aberrant Lipid Homeostasis of Alveolar Cells
Am J Respir Cell Mol Biol. 2021 Apr;64(4):504-514. doi: 10.1165/rcmb.2020-0119OC.
Yin X, Riva L, Pu Y, Martin-Sancho L, Kanamune J, Yamamoto Y, Sakai K, Gotoh S, Miorin L, De Jesus PD, Yang CC, Herbert KM, Yoh S, Hultquist JF, García-Sastre A, Chanda SK.
MDA5 Governs the Innate Immune Response to SARS-CoV-2 in Lung Epithelial Cells
Cell Rep. 2021 Jan 12;34(2):108628. doi: 10.1016/j.celrep.2020.108628.
Maruno T, Fukuda A, Goto N, Tsuda M, Ikuta K, Hiramatsu Y, Ogawa S, Nakanishi Y, Yamaga Y, Yoshioka T, Takaori K, Uemoto S, Saur D, Chiba T, Seno H.
Visualization of stem cell activity in pancreatic cancer expansion by direct lineage tracing with live imaging
Elife. 2021 Jan 4;10:e55117. doi: 10.7554/eLife.55117.
Qiu H, Fujisawa S, Nozaki S, Katoh Y, Nakayama K.
Interaction of INPP5E with ARL13B is essential for its ciliary membrane retention but dispensable for its ciliary entry
Biol Open. 2021 Jan 25;10(1):bio057653. doi: 10.1242/bio.057653.
Suzuki R, Murata MM, Manguso N, Watanabe T, Mouakkad-Montoya L, Igari F, Rahman MM, Qu Y, Cui X, Giuliano AE, Takeda S, Tanaka H.
The fragility of a structurally diverse duplication block triggers recurrent genomic amplification
Nucleic Acids Res. 2021 Jan 11;49(1):244-256. doi: 10.1093/nar/gkaa1136.
Nojima S, Fujita Y, Kimura KT, Nomura N, Suno R, Morimoto K, Yamamoto M, Noda T, Iwata S, Shigematsu H, Kobayashi T.
Cryo-EM Structure of the Prostaglandin E Receptor EP4 Coupled to G Protein
Structure. 2021 Mar 4;29(3):252-260.e6. doi: 10.1016/j.str.2020.11.007. Epub 2020 Dec 1.
Kanagaki S, Ikeo S, Suezawa T, Yamamoto Y, Seki M, Hirai T, Hagiwara M, Suzuki Y, Gotoh S.
Directed induction of alveolar type I cells derived from pluripotent stem cells via Wnt signaling inhibition
Stem Cells. 2021 Feb;39(2):156-169. doi: 10.1002/stem.3302. Epub 2020 Nov 26.
Kato T, Harada N, Ikeguchi-Ogura E, Sankoda A, Hatoko T, Lu X, Yasuda T, Yamane S, Inagaki N.
Gene expression of nutrient-sensing molecules in I cells of CCK reporter male mice
J Mol Endocrinol. 2021 Jan;66(1):11-22. doi: 10.1530/JME-20-0134.
Hirose Y, Hashiya K, Bando T, Sugiyama H.
Evaluation of the DNA Alkylation Properties of a Chlorambucil-Conjugated Cyclic Pyrrole-Imidazole Polyamide
Chemistry. 2021 Feb 5;27(8):2782-2788. doi: 10.1002/chem.202004421. Epub 2021 Jan 14.
Matsuoka T, Motozono C, Hattori A, Kakeya H, Yamasaki S, Oishi S, Ohno H, Inuki S.
The effects of 5-OP-RU stereochemistry on its stability and MAIT-MR1 axis
Chembiochem. 2021 Feb 15;22(4):672-678. doi: 10.1002/cbic.202000466. Epub 2020 Nov 16.
Ryotaro Yagita, Prof. Dr. Kazuhiro Irie, Dr. Chihiro Tsukano
Studies Toward the Total Synthesis of Schinortriterpenoids: Diastereoselective Synthesis of the Left-Hand Fragment
Eur. J. Org. Chem. 2021 May 07 doi:10.1002/ejoc.202100510
Ayumi Uchino, Dr. Chihiro Tsukano, Prof. Dr. Tsuneo Imamoto, Prof. Dr. Kazuhiro Irie
Synthesis of Alkyl Bridged-Tris-α-Amino Acids as C3- Symmetric and Linear Linkers
Eur. J. Org. Chem. 2021 Jan 25 doi:10.1002/ejoc.202001592
Kohta Yamasaki, Akiho Yamauchi, Dr. Tsubasa Inokuma, Yasunori Miyakawa, Dr. Yinli Wang, Dr. Raphaël Oriez, Dr. Yousuke Yamaoka, Prof. Dr. Kiyosei Takasu, Prof. Dr. Naonobu Tanaka, Prof. Dr. Yoshiki Kashiwada, Prof. Dr. Ken-ichi Yamada
Mechanistic Support for Intramolecular Migrative Cyclization of Propargyl Sulfones Provided by Catalytic Asymmetric Induction with a Chiral Counter Cation Strategy
Asian J. Org. Chem. 2021 Apr 16 doi:10.1002/ajoc.202100274
Ken-ichi Yamada, Shinichi Fujiwara , Tsubasa Inokuma, Masayuki Sugano, Yousuke Yamaoka, Kiyosei Takasu
The rationale for stereoinduction in conjugate addition to alkylidenemalonates bearing a menthol-derived chiral auxiliary
Tetrahedron 2021 Jul 2 doi:10.1016/j.tet.2021.132220
Hisashi Hashimoto, Dr. Yoshihiro Ueda, Kiyosei Takasu, Prof. Takeo Kawabata
Catalytic Substrate-Selective Silylation of Primary Alcohols via Remote Functional-Group Discrimination
Angew. Chem. Int. Ed. 2021 Dec 23 doi:10.1002/ange.202114118
武長徹
ラッサウイルスの細胞侵入阻害薬の開発
生体の科学 72巻4号 (2021年8月)
2020
Rahman MM, Mohiuddin M, Shamima Keka I, Yamada K, Tsuda M, Sasanuma H, Andreani J, Guerois R, Borde V, Charbonnier JB, Takeda S.
Genetic evidence for the involvement of mismatch repair proteins, PMS2 and MLH3, in a late step of homologous recombination
J Biol Chem. 2020 Dec 18;295(51):17460-17475. doi: 10.1074/jbc.RA120.013521.
Takeishi A, Kogashi H, Odagiri M, Sasanuma H, Takeda S, Yasui M, Honma M, Suzuki T, Kamiya H, Sugasawa K, Ura K, Sassa A.
Tyrosyl-DNA phosphodiesterases are involved in mutagenic events at a ribonucleotide embedded into DNA in human cells
PLoS One. 2020 Dec 31;15(12):e0244790. doi: 10.1371/journal.pone.0244790. eCollection 2020.
Matsunaga M, Kita T, Yamamoto R, Yamamoto N, Okano T, Omori K, Sakamoto S, Nakagawa T.
Initiation of Supporting Cell Activation for Hair Cell Regeneration in the Avian Auditory Epithelium: An Explant Culture Model
Front Cell Neurosci. 2020 Nov 12;14:583994. doi: 10.3389/fncel.2020.583994. eCollection 2020.
Noura M, Morita K, Kiyose H, Matsuo H, Nishinaka-Arai Y, Kurokawa M, Kamikubo Y, Adachi S.
Pivotal role of DPYSL2A in KLF4-mediated monocytic differentiation of acute myeloid leukemia cells
Sci Rep. 2020 Nov 20;10(1):20245. doi: 10.1038/s41598-020-76951-0.
Shiimura Y, Horita S, Hamamoto A, Asada H, Hirata K, Tanaka M, Mori K, Uemura T, Kobayashi T, Iwata S, Kojima M.
Structure of an antagonist-bound ghrelin receptor reveals possible ghrelin recognition mode
Nat Commun. 2020 Aug 19;11(1):4160. doi: 10.1038/s41467-020-17554-1.
Okazaki M, Kobayashi T, Chiba S, Takei R, Liang L, Nakayama K, Katoh Y.
Formation of the B9-domain protein complex MKS1-B9D2-B9D1 is essential as a diffusion barrier for ciliary membrane proteins
Mol Biol Cell. 2020 Sep 15;31(20):2259-2268. doi: 10.1091/mbc.E20-03-0208. Epub 2020 Jul 29.
Morita D, Iwashita C, Mizutani T, Mori N, Mikami B, Sugita M.
Crystal structure of the ternary complex of TCR, MHC class I and lipopeptides
Int Immunol. 2020 Nov 23;32(12):805-810. doi: 10.1093/intimm/dxaa050.
Maeda R, Ito S, Hashiya K, Bando T, Sugiyama H.
DNA Alkylation of the RUNX-Binding Sequence by CBI-PI Polyamide Conjugates*
Chemistry. 2020 Nov 17;26(64):14639-14644. doi: 10.1002/chem.202002166. Epub 2020 Oct 6.
Nakano T, Shoulkamy MI, Tsuda M, Sasanuma H, Hirota K, Takata M, Masunaga SI, Takeda S, Ide H, Bessho T, Tano K.
Participation of TDP1 in the repair of formaldehyde-induced DNA-protein cross-links in chicken DT40 cells
PLoS One. 2020 Jun 26;15(6):e0234859. doi: 10.1371/journal.pone.0234859. eCollection 2020.
Nyuzuki H, Ito S, Nagasaki K, Nitta Y, Matsui N, Saitoh A, Matsui H.
Degeneration of dopaminergic neurons and impaired intracellular trafficking in Atp13a2 deficient zebrafish
IBRO Rep. 2020 Jun 1;9:1-8. doi: 10.1016/j.ibror.2020.05.002. eCollection 2020 Dec.
Saha LK, Wakasugi M, Akter S, Prasad R, Wilson SH, Shimizu N, Sasanuma H, Huang SN, Agama K, Pommier Y, Matsunaga T, Hirota K, Iwai S, Nakazawa Y, Ogi T, Takeda S.
Topoisomerase I-driven repair of UV-induced damage in NER-deficient cells
Proc Natl Acad Sci U S A. 2020 Jun 23;117(25):14412-14420. doi: 10.1073/pnas.1920165117. Epub 2020 Jun 8.
Nakai S, Oyabu M, Hatazawa Y, Akashi S, Kitamura T, Miura S, Kamei Y.
FOXO1 suppresses PGC-1β gene expression in skeletal muscles
FEBS Open Bio. 2020 Jul;10(7):1373-1388. doi: 10.1002/2211-5463.12898.
Zou Y, Ito S, Yoshino F, Suzuki Y, Zhao L, Komatsu N.
Polyglycerol Grafting Shields Nanoparticles from Protein Corona Formation to Avoid Macrophage Uptake
ACS Nano. 2020 Jun 23;14(6):7216-7226. doi: 10.1021/acsnano.0c02289. Epub 2020 May 20.
Nishimura F, Mogami H, Moriuchi K, Chigusa Y, Mandai M, Kondoh E.
Mechanisms of thrombin-Induced myometrial contractions: Potential targets of progesterone
PLoS One. 2020 May 4;15(5):e0231944. doi: 10.1371/journal.pone.0231944. eCollection 2020.
Akagawa R, Trinh HT, Saha LK, Tsuda M, Hirota K, Yamada S, Shibata A, Kanemaki MT, Nakada S, Takeda S, Sasanuma H.
UBC13-Mediated Ubiquitin Signaling Promotes Removal of Blocking Adducts from DNA Double-Strand Breaks
iScience. 2020 Apr 24;23(4):101027. doi: 10.1016/j.isci.2020.101027. Epub 2020 Mar 31.
Al Mahmud MR, Ishii K, Bernal-Lozano C, Delgado-Sainz I, Toi M, Akamatsu S, Fukumoto M, Watanabe M, Takeda S, Cortés-Ledesma F, Sasanuma H.
TDP2 suppresses genomic instability induced by androgens in the epithelial cells of prostate glands
Genes Cells. 2020 Jul;25(7):450-465. doi: 10.1111/gtc.12770. Epub 2020 May 5.
Shima Y, Morita D, Mizutani T, Mori N, Mikami B, Sugita M.
Crystal structures of lysophospholipid-bound MHC class I molecules
J Biol Chem. 2020 May 15;295(20):6983-6991. doi: 10.1074/jbc.RA119.011932. Epub 2020 Apr 8.
Ibrahim MA, Yasui M, Saha LK, Sasanuma H, Honma M, Takeda S.
Enhancing the sensitivity of the thymidine kinase assay by using DNA repair-deficient human TK6 cells
Environ Mol Mutagen. 2020 Jul;61(6):602-610. doi: 10.1002/em.22371. Epub 2020 Apr 15.
Hasegawa T, Ikeda HO, Gotoh N, Iida K, Iwai S, Nakano N, Kakizuka A, Tsujikawa A.
Effect of VCP modulators on gene expression profiles of retinal ganglion cells in an acute injury mouse model
Sci Rep. 2020 Mar 6;10(1):4251. doi: 10.1038/s41598-020-61160-6.
Itou J, Takahashi R, Sasanuma H, Tsuda M, Morimoto S, Matsumoto Y, Ishii T, Sato F, Takeda S, Toi M.
Estrogen Induces Mammary Ductal Dysplasia via the Upregulation of Myc Expression in a DNA-Repair-Deficient Condition
iScience. 2020 Feb 21;23(2):100821. doi: 10.1016/j.isci.2020.100821. Epub 2020 Jan 9.
de Las Rivas M, Paul Daniel EJ, Narimatsu Y, Compañón I, Kato K, Hermosilla P, Thureau A, Ceballos-Laita L, Coelho H, Bernadó P, Marcelo F, Hansen L, Maeda R, Lostao A, Corzana F, Clausen H, Gerken TA, Hurtado-Guerrero R.
Molecular basis for fibroblast growth factor 23 O-glycosylation by GalNAc-T3
Nat Chem Biol. 2020 Mar;16(3):351-360. doi: 10.1038/s41589-019-0444-x. Epub 2020 Jan 13.
Asada H, Inoue A, Ngako Kadji FM, Hirata K, Shiimura Y, Im D, Shimamura T, Nomura N, Iwanari H, Hamakubo T, Kusano-Arai O, Hisano H, Uemura T, Suno C, Aoki J, Iwata S.
The Crystal Structure of Angiotensin II Type 2 Receptor with Endogenous Peptide Hormone
Structure. 2020 Apr 7;28(4):418-425.e4. doi: 10.1016/j.str.2019.12.003. Epub 2019 Dec 30.
Malinee M, Kumar A, Hidaka T, Horie M, Hasegawa K, Pandian GN, Sugiyama H.
Targeted suppression of metastasis regulatory transcription factor SOX2 in various cancer cell lines using a sequence-specific designer pyrrole-imidazole polyamide
Bioorg Med Chem. 2020 Feb 1;28(3):115248. doi: 10.1016/j.bmc.2019.115248. Epub 2019 Dec 6.
Abe H, Satoh J, Shirasaka Y, Kogure A, Kato H, Ito S, Fujita T.
Priming Phosphorylation of TANK-Binding Kinase 1 by IκB Kinase β Is Essential in Toll-Like Receptor 3/4 Signaling
Mol Cell Biol. 2020 Feb 12;40(5):e00509-19. doi: 10.1128/MCB.00509-19. Print 2020 Feb 12.
Egawa G, Egawa K, Kabashima K.
Case of chickenpox in which varicella zoster virus genotype E was identified for the first time in Japan
J Dermatol. 2020 Jan;47(1):54-57. doi: 10.1111/1346-8138.15153. Epub 2019 Nov 19.
2019
Hirata CL, Ito S, Masutani H.
Dataset on the formation of Thioredoxin interacting protein (Txnip) containing redox sensitive high molecular weight nucleoprotein complexes
Data Brief. 2019 Nov 29;28:104893. doi: 10.1016/j.dib.2019.104893. eCollection 2020 Feb.
Nomura N, Nomura Y, Sato Y, Iwata S.
Crystallographic approaches to study the interaction modes of PD-1- and CTLA-4-blocking antibodies
Methods Enzymol. 2019;629:383-399. doi: 10.1016/bs.mie.2019.10.008. Epub 2019 Oct 29.
Morimoto S, Tsuda M, Bunch H, Sasanuma H, Austin C, Takeda S.
Type II DNA Topoisomerases Cause Spontaneous Double-Strand Breaks in Genomic DNA
Genes (Basel). 2019 Oct 30;10(11):868. doi: 10.3390/genes10110868.
Hirata CL, Ito S, Masutani H.
Thioredoxin interacting protein (Txnip) forms redox sensitive high molecular weight nucleoprotein complexes
Arch Biochem Biophys. 2019 Nov 30;677:108159. doi: 10.1016/j.abb.2019.108159. Epub 2019 Oct 24.
Sassa A, Tada H, Takeishi A, Harada K, Suzuki M, Tsuda M, Sasanuma H, Takeda S, Sugasawa K, Yasui M, Honma M, Ura K.
Processing of a single ribonucleotide embedded into DNA by human nucleotide excision repair and DNA polymerase η
Sci Rep. 2019 Sep 26;9(1):13910. doi: 10.1038/s41598-019-50421-8.
Mukai Y, Tomita Y, Kryukov K, Nakagawa S, Ozawa M, Matsui T, Tomonaga K, Imanishi T, Kawaoka Y, Watanabe T, Horie M.
Identification of a distinct lineage of aviadenovirus from crane feces
Virus Genes. 2019 Dec;55(6):815-824. doi: 10.1007/s11262-019-01703-w. Epub 2019 Sep 23.
Kinjo T, Terai K, Horita S, Nomura N, Sumiyama K, Togashi K, Iwata S, Matsuda M.
FRET-assisted photoactivation of flavoproteins for in vivo two-photon optogenetics
Nat Methods. 2019 Oct;16(10):1029-1036. doi: 10.1038/s41592-019-0541-5. Epub 2019 Sep 9.
Watanabe K, Kanaoka Y, Mizutani S, Uchiyama H, Yajima S, Watada M, Uemura T, Hattori Y.
Interspecies Comparative Analyses Reveal Distinct Carbohydrate-Responsive Systems among Drosophila Species
Cell Rep. 2019 Sep 3;28(10):2594-2607.e7. doi: 10.1016/j.celrep.2019.08.030.
Nozaki S, Castro Araya RF, Katoh Y, Nakayama K.
Requirement of IFT-B-BBSome complex interaction in export of GPR161 from cilia
Biol Open. 2019 Sep 17;8(9):bio043786. doi: 10.1242/bio.043786.
Gothe HJ, Bouwman BAM, Gusmao EG, Piccinno R, Petrosino G, Sayols S, Drechsel O, Minneker V, Josipovic N, Mizi A, Nielsen CF, Wagner EM, Takeda S, Sasanuma H, Hudson DF, Kindler T, Baranello L, Papantonis A, Crosetto N, Roukos V.
Spatial Chromosome Folding and Active Transcription Drive DNA Fragility and Formation of Oncogenic MLL Translocations
Mol Cell. 2019 Jul 25;75(2):267-283.e12. doi: 10.1016/j.molcel.2019.05.015. Epub 2019 Jun 12.
Yamamoto K, Kitawaki T, Sugimoto N, Fujita H, Kawase Y, Takaori-Kondo A, Kadowaki N.
Anti-inflammatory modulation of human myeloid-derived dendritic cell subsets by lenalidomide
Immunol Lett. 2019 Jul;211:41-48. doi: 10.1016/j.imlet.2019.05.012. Epub 2019 May 26.
Kanaoka Y, Skibbe H, Hayashi Y, Uemura T, Hattori Y.
DeTerm: Software for automatic detection of neuronal dendritic branch terminals via an artificial neural network
Genes Cells. 2019 Jul;24(7):464-472. doi: 10.1111/gtc.12700. Epub 2019 May 28.
Okuyama H, Ohnishi H, Nakamura R, Yamashita M, Kishimoto Y, Tateya I, Suehiro A, Gotoh S, Takezawa T, Nakamura T, Omori K.
Transplantation of multiciliated airway cells derived from human iPS cells using an artificial tracheal patch into rat trachea
J Tissue Eng Regen Med. 2019 Jun;13(6):1019-1030. doi: 10.1002/term.2849. Epub 2019 Apr 24.
Mizumoto A, Ohashi S, Kamada M, Saito T, Nakai Y, Baba K, Hirohashi K, Mitani Y, Kikuchi O, Matsubara J, Yamada A, Takahashi T, Lee H, Okuno Y, Kanai M, Muto M.
Combination treatment with highly bioavailable curcumin and NQO1 inhibitor exhibits potent antitumor effects on esophageal squamous cell carcinoma
J Gastroenterol. 2019 Aug;54(8):687-698. doi: 10.1007/s00535-019-01549-x. Epub 2019 Feb 8.