活動成果
目次
・ 利用者数の概要
・ 業績報告ご協力のお願い
・ 利用者業績一覧
利用者数の概要
- 2025年度 : 1527名(2月17日まで)
- 2024年度 : 1466名
- 2023年度 : 1353名
- 2022年度 : 1251名
- 2021年度 : 1112名
業績報告ご協力のお願い
iSALに参画するコアファシリティは、学内予算の他、複数のプロジェクトのサポートのもとに活動を行っています。活動の成果を把握するため、利用者の皆様には研究業績の収集にご協力をお願いします。
iSALが提供するサービスを活用して得られた結果を含めて発表した各種業績について、①Googleフォーム・②EXCELファイルいずれかの方法でご提出をお願いします。
皆様から頂いた情報をもとに論文掲載数や学会発表数などを集計し、iSAL運営に関連するプロジェクトの申請書・報告書等に活用させていただきます。またお寄せいただいた業績報告のうち、学術誌に掲載された論文については、追って「利用者業績一覧」に掲載させていただきます。
ご理解・ご協力どうぞよろしくお願いいたします。
①業績報告回答フォーム(Googleフォーム)
個人単位で回答いただく場合を想定したフォームです。複数ある場合は繰り返しご回答いただくか、②EXCELファイルで作成をお願いします。
○ 学術論文掲載
○ 学会発表
○ 上記以外の業績(特許出願など)
②業績報告書(EXCELファイル)
下記様式(EXCELファイル)をダウンロードして必要事項を入力し、下記提出先にお送りください。研究室単位で回答いただいても個人単位で回答いただいても結構です。
○ 学術論文掲載
○ 学会発表
○ 上記以外の業績(特許出願など)
◎ 提出先 : mrsc_and_isal_office[@]mail2.adm.kyoto-u.ac.jp
※アットマークのカッコを外し、半角英数に直してご使用下さい。
Q & A
Q1. 1つの発表に2名以上の利用者が含まれますがどのように回答したらよいでしょうか。
A1. 「利用者氏名」の欄に発表に関係する利用者全員の氏名を入力してください。
Q2. 2024年度までの関連する業績を報告する必要はありますか。
A2. 過去に各支援担当にご連絡いただいた業績はiSAL内で共有しますので
改めて報告いただく必要はありません。未報告の場合はぜひご協力をお願いします。
Q3. 以前業績報告をしたかどうか定かではありませんが、
重複することになっても報告して良いでしょうか。
A3. はい、問題ありません。過去の記録と照らし合わせ、
重複している場合はこちらで削除します。
Q4. 機密事項など外部に開示できないものについて報告する必要はありますか。
A4. いいえ、ありません。学術論文掲載など公に発表したものだけで結構です。
Q5. iSALの支援を使用していない業績ついて報告する必要はありますか。
A5. いいえ、ありません。
Q6. (年度末のみ)業績報告協力依頼のメールをいただきましたが、
今期は関連する業績がありません。何か連絡する必要はありますか。
A6. いいえ、ありません。
業績報告はいつでもHP上から登録可能ですので
発表された際にはご協力いただけますと幸いです。
利用者業績一覧
○ 論文掲載情報は 50 件ごとに表示しています。ページ下部よりページ切替が可能です。
○ 左上の設定で、1画面に表示する件数を変更できます。
○ 右上の検索ボックスにキーワードを入力すると、絞り込み表示が可能です。
No. Publication
1 Hasegawa T, Nakashima K, Watanabe H, Ono M.
Dual pharmacokinetic modifier strategy for synergistically enhanced tumor accumulation of PSMA-targeting radioligand.
Chem Commun (Camb). 2026 Feb 26;62(16):4851-4854. doi: 10.1039/d5cc06620d.
2 Shinoda H, Makino A, Yoshimura M, Minagawa N, Iida T, Nakano M, Noda T, Toyoda M, Watanabe R.
Multicolor Amplification-Free RNA Detection with Cas13a and Cas13b.
Anal Chem. 2026 Feb 17;98(6):4705-4714. doi: 10.1021/acs.analchem.5c06305. Epub 2026 Feb 3.
3 Moriyama Y, Sada H, Nanjo T.
Making Blank Faces Expressive: Chemical Approaches to the Modification of Chemically Inert Peptides.
J Pept Sci. 2026 Mar;32(3):e70067. doi: 10.1002/psc.70067.
4 Hayashi Y, Tsuyama T, Usui T, Ohbayashi T, Kondo T, Kokuryoh K, Awaya T, Katsuno T, Uemura T.
Roles of a Drosophila ADAM 10 Transmembrane Metalloprotease, Kuzbanian, in Tissue Architecture and Function of the Adult Adipose Tissue.
Genes Cells. 2026 Jan;31(1):e70084. doi: 10.1111/gtc.70084.
5 Yamamoto Y, Takenaka S, Arichi N, Inuki S, Ohno H.
Gold-Catalyzed Cyclization of Pyrrole-Tethered Allenynes for the Synthesis of 4-Acylindoles and Its Application to the Ergot Alkaloid Scaffold.
Org Lett. 2026 Jan 30;28(4):1331-1336. doi: 10.1021/acs.orglett.5c05144. Epub 2026 Jan 16.
6 Morita D, Fujii T, Inuki S, Suzuki H, Mikami B, Sugita M.
Lipopeptide ligands captured by MHC class I molecules undergo dynamic conformational changes that affect their antigenic strength.
J Biol Chem. 2026 Feb;302(2):111049. doi: 10.1016/j.jbc.2025.111049. Epub 2025 Dec 12.
7 Shimamoto N, Arichi N, Ohno H.
Triplet nitrene-mediated photocatalytic azidation of tertiary C(sp(3))-H bonds.
Chem Commun (Camb). 2026 Jan 6;62(1):164-167. doi: 10.1039/d5cc05587c.
8 Arai M, Kawakami R, Nakamura Y, Naito Y, Motooka D, Sugimoto A, Kimoto T, Ohkura N, Mikami N, Sakaguchi S.
Oral antigen exposure under costimulation blockade induces Treg cells to establish immune tolerance.
J Exp Med. 2026 Jan 5;223(3):e20251635. doi: 10.1084/jem.20251635. Epub 2025 Oct 21.
9 Nakamura R, Kishimoto Y, Kita T, Yoshie S, Kaba S, Okuno Y, Omori K.
Verteporfin, an inhibitor of nuclear YAP, improved multi-ciliated cell differentiation in the airway epithelium.
J Transl Med. 2025 Dec 23;24(1):217. doi: 10.1186/s12967-025-07250-3.
10 Kiuchi M, Nemoto M, Yagyu H, Aoki A, Iwamura C, Sugimoto H, Masuo Y, Morita H, Ma S, Okuno Y, Hishiya T, Tsuji K, Sasaki A, Kokubo K, Ohishi K, Shinmi R, Sonobe Y, Iinuma T, Yonekura S, Yokomizo T, Komatsu N, Onodera A, Okumura S, Ito T, Hatano E, Tsuruyama T, Kurashima Y, Mato N, Suzuki T, Kimura MY, Motohashi S, Kawakami E, Ueno H, Tumes DJ, Hanazawa T, Nakayama T, Hirahara K.
Hepatic leukemia factor directs tissue residency of proinflammatory memory CD4(+) T cells.
Science. 2025 Dec 11;390(6778):eadp0714. doi: 10.1126/science.adp0714. Epub 2025 Dec 11.
11 Kinouchi H, Ito T, Kohyama A, Kuroda Y, Takikawa H, Takasu K.
Synthesis and Properties of Medium-Sized cis,trans-Cycloocta-1,3-diene-Pt(II) Complexes.
Org Lett. 2025 Dec 19;27(50):13922-13927. doi: 10.1021/acs.orglett.5c04468. Epub 2025 Dec 4.
12 Matsuura R, Punyawatthananukool S, Kawakami R, Mikami N, Sakaguchi S, Narumiya S.
Prostaglandin E(2)-EP2/EP4 signaling induces the tumor-infiltrating Treg phenotype for tumor growth.
Proc Natl Acad Sci U S A. 2025 Dec 9;122(49):e2424251122. doi: 10.1073/pnas.2424251122. Epub 2025 Dec 4.
13 Yamauchi M, Im D, Maeda S, Ikuta T, Toyomoto M, Asada H, Sugita Y, Kishikawa JI, Noda T, Kato T, Inoue A, Iwata S, Hagiwara M.
Structural insights into the G-protein subtype selectivity revealed by human sphingosine-1-phosphate receptor 3-G(q) complexes.
Proc Natl Acad Sci U S A. 2025 Nov 25;122(47):e2507421122. doi: 10.1073/pnas.2507421122. Epub 2025 Nov 18.
14 Wu P, Yokota K, Yasuma N, Hakamada M, Mabuchi M.
Fabrication of Millimeter-Sized Three-Dimensional In Vitro Tissues with High Cellular Density and Hierarchical Vascular Networks.
ACS Biomater Sci Eng. 2025 Dec 8;11(12):7474-7487. doi: 10.1021/acsbiomaterials.5c01685. Epub 2025 Nov 14.
15 Nishiyama K, Akiba H, Tsutsui Y, Kamada H, Ohno H.
Design Strategy of Antibody Pairs for Biepitopic Antigen-Templated Chemical Reaction Depending on the Tertiary Structure of the Antigen.
Chemistry. 2025 Dec 17;31(71):e01803. doi: 10.1002/chem.202501803. Epub 2025 Nov 10.
16 Kawano K, Hosokawa K, Taniguchi A, Oosugi Y, Soga A, Kawamoto J, Kuzuma Y, Matsuzaki K.
Curvature-Sensing Peptide Functions as a Membrane Interfactant That Glues Small Extracellular Vesicles to Cell Membranes and Enhances Vesicle Cellular Uptake.
ACS Appl Bio Mater. 2025 Dec 15;8(12):10839-10854. doi: 10.1021/acsabm.5c01541. Epub 2025 Nov 7.
17 Suno-Ikeda C, Nishikawa R, Suzuki R, Yokoi S, Iwata S, Takai T, Ogura T, Hirose M, Tokuda A, Katamoto R, Inoue A, Asai E, Kise R, Sugita Y, Kato T, Nagase H, Mitsutake A, Saitoh T, Katayama K, Inoue A, Kandori H, Kobayashi T, Suno R.
Structural and dynamic insights into the biased signaling mechanism of the human kappa opioid receptor.
Nat Commun. 2025 Oct 28;16(1):9392. doi: 10.1038/s41467-025-64882-1.
18 Watanabe H, Saito H, Nakashima K, Ono M.
Structure-Activity Relationships of Azaquinazolinone Derivatives as (18)F-Labeled PET Probes Targeting Ghrelin Receptors.
J Med Chem. 2025 Nov 13;68(21):22288-22300. doi: 10.1021/acs.jmedchem.5c01070. Epub 2025 Oct 27.
19 Mikami N, Kawakami R, Sugimoto A, Arai M, Sakaguchi S.
Generating functionally stable and antigen-specific T(reg) cells from effector T cells for cell therapy of inflammatory diseases.
Sci Transl Med. 2025 Oct 22;17(821):eadr6049. doi: 10.1126/scitranslmed.adr6049. Epub 2025 Oct 22.
20 Akasaka T, Watanabe H, Ono M.
Novel BODIPY-Based Fluorescent Probes with Improved Aqueous Solubility for Selective Detection of Soluble Aβ Aggregates.
ACS Chem Neurosci. 2025 Nov 5;16(21):4257-4266. doi: 10.1021/acschemneuro.5c00525. Epub 2025 Oct 15.
21 Zhang N, Sano T, Ito K, Ito S, Ikeuchi R, Takada H, Nakamura K, Sakatani T, Hamada A, Takeda M, Murakami K, Kita Y, Sumiyoshi T, Goto T, Saito R, Ogawa O, Matsuda M, Kobayashi T.
Urothelial collective-gliding response acts as a toll-like receptor 4-associated defense mechanism.
iScience. 2025 Sep 12;28(10):113553. doi: 10.1016/j.isci.2025.113553. eCollection 2025 Oct 17.
22 Takamatsu Y, Dolnik O, Hirabayashi A, Okamoto K, Kurashige T, Shangfan H, Oda Harumi C, Noda T.
Molecular insights into nucleocapsid assembly and transport in Marburg and Ebola viruses.
mBio. 2025 Nov 12;16(11):e0155725. doi: 10.1128/mbio.01557-25. Epub 2025 Sep 22.
23 Shimamoto N, Arichi N, Inuki S, Ohno H.
Photoinduced Azidosulfonylative Cyclization of 1,6-Dienes with Sulfonyl Azides.
Chem Pharm Bull (Tokyo). 2025;73(9):831-834. doi: 10.1248/cpb.c25-00437.
24 Kawano K, Hoshino T, Yano Y, Matsuzaki K.
Steady dimer formation by the S31N mutant of influenza A virus M2 protein in living cell membranes.
Biochim Biophys Acta Biomembr. 2025 Dec;1867(8):184456. doi: 10.1016/j.bbamem.2025.184456. Epub 2025 Sep 9.
25 Nakano M, Miyamoto S, Ohnishi C, Nogami C, Hirose N, Fujita-Fujiharu Y, Muramoto Y, Noda T.
Influenza A virus circumvents the innate immune response through the sequestration of double-stranded RNA.
J Virol. 2025 Oct 23;99(10):e0073725. doi: 10.1128/jvi.00737-25. Epub 2025 Sep 8.
26 Murai J, Abdelmoez MN, Kondo K, Takamuro K, Nozaki K, Schiller T, Scheibel TR, Numata K, Yajima H, Kimura KT, Hashiguchi T, Kaneko T, Minegishi M, Shintaku H.
An open source for multiplexed, stable and transient flows to advance life sciences using microfluidic control automation.
Lab Chip. 2025 Oct 7;25(20):5302-5317. doi: 10.1039/d5lc00551e.
27 Kawajiri M, Kuroda Y, Takasu K.
Net δ-C-H Alkylation of Allyl Alcohols by Ni-Catalyzed Allylic Substitution of Azo-Ene Adducts.
J Org Chem. 2025 Sep 12;90(36):12826-12831. doi: 10.1021/acs.joc.5c01497. Epub 2025 Aug 29.
28 Betsuyaku T, Akizuki S, Liu Y, Morinobu A.
Activated human B cells produce phospholipase D4-containing extracellular vesicles.
PLoS One. 2025 Aug 14;20(8):e0329832. doi: 10.1371/journal.pone.0329832. eCollection 2025.
29 Matsuda M, Fujiwara Y, Yonezawa F, Matsuo K, Ishizu E, Shimora H, Shimizu S, Kitatani K, Kaibori Y, Yamagishi N, Yashiro T, Moro K, Kawakami R, Mikami N, Sakaguchi S, Nabe T.
Cyclin-dependent kinase (CDK) 8 and its paralog CDK19 develop group 2 innate lymphoid cell-related lung fibrosis by activating STAT5.
J Immunol. 2025 Dec 1;214(12):3238-3249. doi: 10.1093/jimmun/vkaf171.
30 Hasegawa D, Arichi N, Ohno H.
Stereoselective Synthesis of Spirocyclic Indolin-3-ones through a Gold(I)-Catalyzed Cascade Cyclization of Azido-alkynes.
J Org Chem. 2025 Aug 15;90(32):11737-11741. doi: 10.1021/acs.joc.5c01284. Epub 2025 Aug 6.
31 Sugimoto K, Nagao T, Kurokawa K, Tawatari T, Miyakawa Y, Fujimura S, Yamada KI, Yamaoka Y, Kohyama A, Kuroda Y, Takikawa H, Takasu K.
A Potassium Base-Promoted Intramolecular Enolate-Olefin Metathesis.
Chemistry. 2025 Oct 1;31(55):e00737. doi: 10.1002/chem.202500737. Epub 2025 Aug 6.
32 Otsuki T, Matsumoto S, Fujita J, Miyata T, Namba K, Kanada R, Okuno Y, Kamada H, Ohno H, Akiba H.
Conversion of an agonistic anti-TNFR2 biparatopic antibody into an antagonist by insertion of peptide linkers into the hinge region.
J Biol Chem. 2025 Sep;301(9):110548. doi: 10.1016/j.jbc.2025.110548. Epub 2025 Jul 31.
33 Noji M, Sugita Y, Yamazaki Y, Miyazaki M, Suzuki Y.
Protein design of two-component tubular assemblies similar to cytoskeletons.
Nat Commun. 2025 Jul 22;16(1):6738. doi: 10.1038/s41467-025-62076-3.
34 Naruse C, Ishibashi O, Ohgushi M, Imai H, Matsuzaki T, Pan X, Miyazaki T, Shidahara Y, Shirakawa Y, Sugiyama F, Asano M.
Differential substrate degradation by super-degron: EGFP in wild-type mouse cells, PD-1 requires CRBN humanization.
iScience. 2025 Jun 23;28(7):112992. doi: 10.1016/j.isci.2025.112992. eCollection 2025 Jul 18.
35 Miyazaki R, Kimoto M, Kohga H, Tsukazaki T.
Structural basis of lipopolysaccharide translocon assembly mediated by the small lipoprotein LptM.
Cell Rep. 2025 Aug 26;44(8):116013. doi: 10.1016/j.celrep.2025.116013. Epub 2025 Jul 16.
36 Jikko Y, Deguchi E, Matsuda K, Hino N, Tsukiji S, Matsuda M, Terai K.
Front-biased activation of the Ras-Rab5-Rac1 loop coordinates collective cell migration.
J Cell Sci. 2025 Aug 1;138(15):jcs263779. doi: 10.1242/jcs.263779. Epub 2025 Aug 4.
37 Yadav S, Fujimoto K, Takenaga T, Takahashi S, Muramoto Y, Mikawa R, Noda T, Gotoh S, Yokokawa R.
Isogenic induced-pluripotent-stem-cell-derived airway- and alveolus-on-chip models reveal specific innate immune responses.
Nat Biomed Eng. 2025 Dec;9(12):2028-2042. doi: 10.1038/s41551-025-01444-2. Epub 2025 Jul 16.
38 Matsuo K, Nakajima Y, Shigeta M, Kobayashi D, Sakaki S, Inoue S, Takeshita N, Ueyama A, Nishikawa K, Saba R, Yamasaki H, Yamada K, Yokoyama T, Yashiro K.
Focal adhesion-related non-ciliary functions of CEP290.
PLoS One. 2025 Jul 9;20(7):e0325921. doi: 10.1371/journal.pone.0325921. eCollection 2025.
39 Kado Y, Kawano K, Nishikawa M, Tanaka A, Yano Y, Hoshino M, Matsuzaki K.
Structural Changes of Amyloid β-Protein Fibrils on Neuronal Cells.
ACS Chem Neurosci. 2025 Jul 2;16(13):2387-2394. doi: 10.1021/acschemneuro.5c00064. Epub 2025 Jun 10.
40 Kanao E, Murata Y, Miwa S, Takikawa H, Takasu K, Ishihama Y, Kubo T.
Unveiling the Inverse-Handed Self-Discrimination of Helicenes with Twisted π-Surfaces by Liquid Chromatography.
Anal Chem. 2025 Jun 24;97(24):12690-12698. doi: 10.1021/acs.analchem.5c01385. Epub 2025 Jun 10.
41 Hasegawa T, Nakashima K, Tarumizu Y, Tada M, Maya Y, Watanabe H, Ono M.
Development of Novel Radiotheranostic Ligand with Positively Charged Unit Targeting Prostate-Specific Membrane Antigen.
J Med Chem. 2025 May 22;68(10):10190-10202. doi: 10.1021/acs.jmedchem.5c00370. Epub 2025 May 13.
42 Kato R, Sakaue T, Tawatari T, Takasu K, Takikawa H.
Arylative double bond transposition of allylic alcohols via silicon-tethered intramolecular benzyne-ene reactions.
Chem Commun (Camb). 2025 Jun 3;61(46):8347-8350. doi: 10.1039/d5cc01918d.
43 Zou F, Baba O, Horie T, Nakashima Y, Tsuji S, Yamasaki T, Otani C, Xu S, Imanaka M, Matsushita K, Suzuki K, Kume E, Kojima H, Qian Q, Kimura K, Sowa N, Kakizuka A, Ono K.
KUS121, a novel VCP modulator, attenuates atherosclerosis development by reducing ER stress and inhibiting glycolysis through the maintenance of ATP levels in endothelial cells.
Atherosclerosis. 2025 Jun;405:119223. doi: 10.1016/j.atherosclerosis.2025.119223. Epub 2025 May 1.
44 Suzuki H, Kunimatsu Y, Yoshioka Y, Asa M, Yamasaki S, Sugita M, Morita D.
TAP-independent induction of N-myristoylated lipopeptide-specific CTLs in transgenic mice expressing the rhesus MHC class I allomorph, Mamu-B*098.
J Immunol. 2025 Jul 1;214(7):1483-1492. doi: 10.1093/jimmun/vkaf082.
45 Kashiyama R, Watanabe H, Akasaka T, Ono M. Novel amyloid-β oligomer-targeted fluorescent probes by introducing branched chain into push-pull type dye. Dyes and Pigments. 2025 May 1;236:112680. doi:10.1016/j.dyepig.2025.112680
46 Hashimoto R, Watanabe Y, Keshta A, Sugiyama M, Kitai Y, Hirabayashi A, Yasuhara N, Morimoto S, Sakamoto A, Matsumura Y, Nishimura H, Noda T, Yamamoto T, Nagao M, Takeda M, Takayama K.
Human iPS cell-derived respiratory organoids as a model for respiratory syncytial virus infection.
Life Sci Alliance. 2025 Apr 22;8(7):e202402837. doi: 10.26508/lsa.202402837. Print 2025 Jul.
47 Kitadokoro J, Hirokawa T, Kamo M, Furubayashi N, Okuno Y, Hikima T, Yamamoto M, Inaka K, Maenaka K, Kamitani S, Kitadokoro K.
Structural analysis shows the mode of inhibition for Staphylococcus aureus lipase by antipsychotic penfluridol.
Sci Rep. 2025 Apr 14;15(1):11876. doi: 10.1038/s41598-025-94981-4.
48 Kawakami R, Sakaguchi S.
T(reg) cells augment self-tolerance during infection.
Nat Immunol. 2025 May;26(5):650-652. doi: 10.1038/s41590-025-02141-7.
49 Otani T, Miyake T, Ota T, Yarimizu D, Nakagawa Y, Murai I, Okamura H, Hasegawa E, Doi M.
Identification of angiotensin II-responsive circadian clock gene expression in adrenal zona glomerulosa cells and human adrenocortical H295R cells.
Front Endocrinol (Lausanne). 2025 Mar 26;16:1525844. doi: 10.3389/fendo.2025.1525844. eCollection 2025.
50 Yokoi M, Murakami K, Yaguchi T, Chamoto K, Ozasa H, Yoshida H, Shirakashi M, Ito K, Komohara Y, Fujiwara Y, Yano H, Ogimoto T, Hira D, Terada T, Hirai T, Tsukamoto H.
ICOS+CD4+ T cells define a high susceptibility to anti-PD-1 therapy-induced lung pathogenesis.
JCI Insight. 2025 Apr 8;10(10):e186483. doi: 10.1172/jci.insight.186483. eCollection 2025 May 22.
51 Soma S, Hayatsu N, Nomura K, Sherwood MW, Murakami T, Sugiyama Y, Suematsu N, Aoki T, Yamada Y, Asayama M, Kaneko M, Ohbayashi K, Arizono M, Ohtsuka M, Hamada S, Matsumoto I, Iwasaki Y, Ohno N, Okazaki Y, Taruno A.
Channel synapse mediates neurotransmission of airway protective chemoreflexes.
Cell. 2025 May 15;188(10):2687-2704.e29. doi: 10.1016/j.cell.2025.03.007. Epub 2025 Apr 4.
52 Inoue H, Kawano K, Kawamoto J, Ogawa T, Kurihara T.
Rapid screening and identification of genes involved in bacterial extracellular membrane vesicle production using a curvature-sensing peptide.
J Bacteriol. 2025 May 22;207(5):e0049724. doi: 10.1128/jb.00497-24. Epub 2025 Apr 4.
53 Nanjo T.
Unconventional Synthetic Approaches to Unusual Peptide Derivatives.
Chem Pharm Bull (Tokyo). 2025;73(4):268-282. doi: 10.1248/cpb.c24-00752.
54 Matsuoka T, Takasaki R, Akiba H, Ogata K, Hattori A, Arichi N, Kakeya H, Yamasaki S, Ishihama Y, Ohno H, Inuki S.
Visible light-mediated photocatalytic coupling between tetrazoles and carboxylic acids for biomolecule labelling.
Chem Commun (Camb). 2025 Apr 22;61(34):6320-6323. doi: 10.1039/d4cc04452e.
55 Oyabu M, Ohira Y, Fujita M, Yoshioka K, Kawaguchi R, Kubo A, Hatazawa Y, Yukitoshi H, Ortuste Quiroga HP, Horii N, Miura F, Araki H, Okano M, Hatada I, Gotoh H, Yoshizawa T, Fukada SI, Ogawa Y, Ito T, Ishihara K, Ono Y, Kamei Y.
Dnmt3a overexpression disrupts skeletal muscle homeostasis, promotes an aging-like phenotype, and reduces metabolic elasticity.
iScience. 2025 Mar 3;28(4):112144. doi: 10.1016/j.isci.2025.112144. eCollection 2025 Apr 18.
56 Laporte M, Jochmans D, Bardiot D, Desmarets L, Debski-Antoniak OJ, Mizzon G, Abdelnabi R, Leyssen P, Chiu W, Zhang Z, Nomura N, Boland S, Ohto U, Stahl Y, Wuyts J, De Jonghe S, Stevaert A, van Hemert MJ, Bontes BW, Wanningen P, Groenewold GJM, Zegar A, Owczarek K, Joshi S, Koukni M, Arzel P, Klaassen H, Vanherck JC, Vandecaetsbeek I, Cremers N, Donckers K, Francken T, Van Buyten T, Rymenants J, Schepers J, Pyrc K, Hilgenfeld R, Dubuisson J, Bosch BJ, Van Kuppeveld F, Eydoux C, Decroly E, Canard B, Naesens L, Weynand B, Snijder EJ, Belouzard S, Shimizu T, Bartenschlager R, Hurdiss DL, Marchand A, Chaltin P, Neyts J.
A coronavirus assembly inhibitor that targets the viral membrane protein.
Nature. 2025 Apr;640(8058):514-523. doi: 10.1038/s41586-025-08773-x. Epub 2025 Mar 26.
57 Nakaya M, Iwatani C, Tsukiyama-Fujii S, Mieda A, Tarumoto S, Tsujimura T, Yamamoto T, Ichikawa T, Nakamura T, Terakado I, Kawamoto I, Nakagawa T, Itagaki I, Saitou M, Tsuchiya H, Tsukiyama T.
Non-viral generation of transgenic non-human primates via the piggyBac transposon system.
Nat Commun. 2025 Mar 24;16(1):2179. doi: 10.1038/s41467-025-57365-w.
58 Yumura T, Nanjo T, Takemoto Y. Benzophenothiazine/Boronic Acid Cooperative Photocatalysis Enables the Synthesis of γ-Lactones via the [3 + 2] Cycloaddition of α,β-Unsaturated Carboxylic Acids with Olefins. ACS Catal. 2025 Mar 21;15(6):4975–83. doi:10.1021/acscatal.5c00764
59 Romero-Zamora D, Rogers S, Low RRJ, Page SG, Lane BJE, Kosaka S, Robinson AB, French L, Lamm N, Ishikawa F, Hayashi MT, Cesare AJ.
A CPC-shelterin-BTR axis regulates mitotic telomere deprotection.
Nat Commun. 2025 Mar 17;16(1):2277. doi: 10.1038/s41467-025-57456-8.
60 Tobori S, Tamada K, Uemura N, Sawada K, Kakae M, Nagayasu K, Nakagawa T, Mori Y, Kaneko S, Shirakawa H.
Spinal TRPC3 promotes neuropathic pain and coordinates phospholipase C-induced mechanical hypersensitivity.
Proc Natl Acad Sci U S A. 2025 Mar 18;122(11):e2416828122. doi: 10.1073/pnas.2416828122. Epub 2025 Mar 13.
61 Fujita-Fujiharu Y, Hu S, Hirabayashi A, Takamatsu Y, Ng YN, Houri K, Muramoto Y, Nakano M, Sugita Y, Noda T.
Structural basis for Ebola virus nucleocapsid assembly and function regulated by VP24.
Nat Commun. 2025 Mar 10;16(1):2171. doi: 10.1038/s41467-025-57236-4.
62 Nanjo T, Lin Y, Fujii Y, Takemoto Y.
A Sterically Tuned 2-Fluoropyridinium Salt for the Catalyst-Free, Visible-Light-Mediated Deoxygenation of Alcohols via an Electron Donor-Acceptor Complex.
Org Lett. 2025 Mar 21;27(11):2616-2621. doi: 10.1021/acs.orglett.5c00266. Epub 2025 Mar 7.
63 Hikosaka M, Parvez MSA, Yamawaki Y, Oe S, Liang Y, Wada Y, Hirahara Y, Koike T, Imai H, Oishi N, Schalbetter SM, Kumagai A, Yoshida M, Sakurai T, Kitada M, Meyer U, Narumiya S, Ohtsuki G.
Maternal immune activation followed by peripubertal stress combinedly produce reactive microglia and confine cerebellar cognition.
Commun Biol. 2025 Mar 3;8(1):296. doi: 10.1038/s42003-025-07566-2.
64 Kohyama A, Namioka M, Naka H, Ashikari Y, Nagaki A, Takikawa H, et al. Continuous flow synthesis of cyclobutenes via lithium ynolates. Green Chem. 2025 Mar 3;27(10):2760–5. doi:10.1039/D4GC05102E
65 Iida K, Ajiro M, Nakano-Kobayashi A, Muramoto Y, Takenaga T, Denawa M, Kurosawa R, Noda T, Hagiwara M.
Switching of OAS1 splicing isoforms overcomes SNP-derived vulnerability to SARS-CoV-2 infection.
BMC Biol. 2025 Mar 3;23(1):60. doi: 10.1186/s12915-025-02173-3.
66 Fukui T, Okasho K, Okuno Y, Fujiwara M, Hikami K, Fukunaga A, Sunada T, Kita Y, Sumiyoshi T, Goto T, Saito R, Ogawa O, Kobayashi T, Akamatsu S.
A highly sensitive screening system to evaluate the reversibility of neuroendocrine prostate cancer to prostate adenocarcinoma.
Cancer Med. 2025 Mar;14(5):e70047. doi: 10.1002/cam4.70047.
67 Nguyen Pham KT, Miyake T, Suzuki T, Kinoshita S, Hamada Y, Uehara H, Machida M, Nakajima T, Hasegawa E, Doi M.
Identification of meibomian gland testosterone metabolites produced by tissue-intrinsic intracrine deactivation activity.
iScience. 2025 Jan 27;28(2):111808. doi: 10.1016/j.isci.2025.111808. eCollection 2025 Feb 21.
68 Ta HKT, Mai NXD, Nguyen HVT, Matsumoto K, Phan TB, Tamanoi F, et al. Development and characterization of magnetic-based biodegradable periodic mesoporous organosilica nanoparticles for enhanced biomedical applications. Journal of Industrial and Engineering Chemistry. 2025 Feb 25;142:563–9. doi:10.1016/j.jiec.2024.07.061
69 Ise W, Koike T, Shimada N, Yamamoto H, Tai Y, Shirai T, Kawakami R, Kuwabara M, Kawai C, Shida K, Inoue T, Hojo N, Ichiyama K, Sakaguchi S, Shiroguchi K, Suzuki K, Kurosaki T.
KLF2 expression in IgG plasma cells at their induction site regulates the migration program.
J Exp Med. 2025 May 5;222(5):e20241019. doi: 10.1084/jem.20241019. Epub 2025 Feb 20.
70 Yamaura K, Takemata N, Kariya M, Osaka A, Ishino S, Yamauchi M, Tamura T, Hamachi I, Takada S, Ishino Y, Atomi H.
Chromosomal domain formation by archaeal SMC, a roadblock protein, and DNA structure.
Nat Commun. 2025 Feb 19;16(1):1312. doi: 10.1038/s41467-025-56197-y.
71 Akiba H, Ise T, Satoh R, Abe Y, Tsumoto K, Ohno H, Kamada H, Nagata S.
Generation of antagonistic biparatopic anti-CD30 antibody from an agonistic antibody by precise epitope determination and utilization of structural characteristics of CD30 molecule.
Antib Ther. 2025 Jan 14;8(1):56-67. doi: 10.1093/abt/tbaf002. eCollection 2025 Jan.
72 Kuroda Y, Chiba T, Kawajiri M, Takasu K.
Pd-Catalyzed Allylic Substitution of Azo-Ene Adducts Enables Net Allylic C-H Alkylation of Allylic Alcohols.
Org Lett. 2025 Feb 14;27(6):1517-1523. doi: 10.1021/acs.orglett.5c00049. Epub 2025 Feb 3.
73 Yasuda E, Kawamura Y, Ueda Y, Takakura M, Matsuzaka Y, Matsuzaka S, Inohaya A, Chigusa Y, Mandai M, Mogami H.
Potential mechanisms for chorioamniotic membrane rupture after subchorionic hematoma.
Am J Obstet Gynecol. 2025 Aug;233(2):125.e1-125.e18. doi: 10.1016/j.ajog.2025.01.031. Epub 2025 Jan 30.
74 Miwa S, Mizutani D, Kawano K, Matsuzaki K, Nagata Y, Tsubaki K, Takasu K, Takikawa H.
Helicene-Fluorescein Hybrids: A Reversible Base-Triggered (Chir)optical Switch with Sign Inversion of Circularly Polarized Luminescence.
Chemistry. 2025 Mar 20;31(17):e202500335. doi: 10.1002/chem.202500335. Epub 2025 Feb 12.
75 Maki J, Oshimura A, Shiotani Y, Yamanaka M, Okuda S, Yanagita RC, Kitani S, Igarashi Y, Saito Y, Sakakibara Y, Tsukano C, Irie K.
Validation of machine learning-assisted screening of PKC ligands: PKC binding affinity and activation.
Biosci Biotechnol Biochem. 2025 Apr 22;89(5):668-679. doi: 10.1093/bbb/zbaf008.
76 Koda M, Kawai H, Shirakawa H, Kaneko S, Nagayasu K.
Effect of antidepressants and social defeat stress on the activity of dorsal raphe serotonin neurons in free-moving animals.
J Pharmacol Sci. 2025 Feb;157(2):113-123. doi: 10.1016/j.jphs.2025.01.001. Epub 2025 Jan 2.
77 Hasegawa D, Tsuji A, Greiner LC, Arichi N, Inuki S, Ohno H.
Synthesis of Azocine-Fused Indoles via Gold(I)-Catalyzed Cyclization of Azido-alkynes.
J Org Chem. 2025 Jan 10;90(1):925-930. doi: 10.1021/acs.joc.4c02704. Epub 2024 Dec 31.
78 Park Y, Matsumoto S, Ogata K, Ma B, Kanada R, Isaka Y, Arichi N, Liang X, Maki R, Kozasa T, Okuno Y, Ohno H, Ishihama Y, Toyoshima F.
Receptor-independent regulation of Gα13 by alpha-1-antitrypsin C-terminal peptides.
J Biol Chem. 2025 Feb;301(2):108136. doi: 10.1016/j.jbc.2024.108136. Epub 2024 Dec 25.
79 Nishikawa K, Murakami T, Yoshida M, Terada N, Ishihara K, Mori Y, Ito S, Tsujikawa A.
Extracellular Mitochondria Exacerbate Retinal Pigment Epithelium Degeneration in Diabetic Retinopathy.
Diabetes. 2025 Mar 1;74(3):409-415. doi: 10.2337/db24-0040.
80 Miyaji T, Yamagami A, Nakamura Y, Nishida K, Tachibana R, Surina S, Fujioka S, Garcia-Hourquet M, Mora-García S, Nosaki S, Miyakawa T, Tanokura M, Matsui M, Osada H, Shinozaki K, Asami T, Nakano T.
BIL7 enhances plant growth by regulating the transcription factor BIL1/BZR1 during brassinosteroid signaling.
Plant J. 2025 Jan;121(2):e17212. doi: 10.1111/tpj.17212. Epub 2024 Dec 20.
81 Hirabayashi A, Muramoto Y, Takenaga T, Tsunoda Y, Wakazaki M, Sato M, Fujita-Fujiharu Y, Nomura N, Yamauchi K, Onishi C, Nakano M, Toyooka K, Noda T.
Coatomer complex I is required for the transport of SARS-CoV-2 progeny virions from the endoplasmic reticulum-Golgi intermediate compartment.
mBio. 2025 Jan 8;16(1):e0333124. doi: 10.1128/mbio.03331-24. Epub 2024 Nov 29.
82 Kitai Y, Toriu N, Yoshikawa T, Sahara Y, Kinjo S, Shimizu Y, Sato Y, Oguchi A, Yamada R, Kondo M, Uchino E, Taniguchi K, Arai H, Sasako T, Haga H, Fukuma S, Kubota N, Kadowaki T, Takasato M, Murakawa Y, Yanagita M.
Female sex hormones inversely regulate acute kidney disease susceptibility throughout life.
Kidney Int. 2025 Jan;107(1):68-83. doi: 10.1016/j.kint.2024.08.034. Epub 2024 Nov 5.
83 Morino K, Miyake M, Nagasaki M, Kawaguchi T, Numa S, Mori Y, Yasukura S, Akada M, Nakao SY, Nakata A, Hashimoto H, Otokozawa R, Kamoi K, Takahashi H, Tabara Y, Matsuda F, Ohno-Matsui K, Tsujikawa A; Nagahama Study Group.
Genome-wide Meta-analysis for Myopic Macular Neovascularization Identified a Novel Susceptibility Locus and Revealed a Shared Genetic Susceptibility with Age-Related Macular Degeneration.
Ophthalmol Retina. 2025 Apr;9(4):367-377. doi: 10.1016/j.oret.2024.09.016. Epub 2024 Nov 1.
84 Miyata Y, Takahashi K, Lee Y, Sultan CS, Kuribayashi R, Takahashi M, Hata K, Bamba T, Izumi Y, Liu K, Uemura T, Nomura N, Iwata S, Nagata S, Nishizawa T, Segawa K.
Membrane structure-responsive lipid scrambling by TMEM63B to control plasma membrane lipid distribution.
Nat Struct Mol Biol. 2025 Jan;32(1):185-198. doi: 10.1038/s41594-024-01411-6. Epub 2024 Oct 18.
85 Mizuno K, Ohnishi H, Kishimoto Y, Kojima T, Fujimura S, Kawai Y, Kitano M, Ikeya M, Omori K.
Rat Tracheal Cartilage Regeneration Using Mesenchymal Stem Cells Derived From Human iPS Cells.
Tissue Eng Part A. 2025 May;31(9-10):398-408. doi: 10.1089/ten.TEA.2024.0151. Epub 2024 Jul 29.
86 Kitano M, Ohnishi H, Makino A, Miyamoto T, Hayashi Y, Mizuno K, Kaba S, Kawai Y, Kojima T, Kishimoto Y, Yamamoto N, Tomonaga K, Omori K.
An Infection Model for SARS-CoV-2 Using Rat Transplanted with hiPSC-Airway Epithelial Cells.
Tissue Eng Part A. 2025 May;31(9-10):361-372. doi: 10.1089/ten.TEA.2024.0016. Epub 2024 Jun 27.
87 Aoki M, Takarada H, Maki J, Kobayashi T, Tsukano C, Irie K. Convergent Synthesis of Antitumor Aplysiatoxin Derivatives Based on a Combination of Ring-Closing and Cross Metathesis. European Journal of Organic Chemistry. 2025;28(3):e202401074. doi:10.1002/ejoc.202401074
88 Suzuki T, Nojo W, Kawada Y, Sugiyama S, Ikeuchi T, Ishigaki Y, et al. Gold(I)-catalyzed Synthesis of Axially Chiral Indolo[2,3-c]carbazole Exhibiting Advanced Electrochromic Response. Asian Journal of Organic Chemistry. 2025;14(3):e202400695. doi:10.1002/ajoc.202400695
89 Yamauchi I, Sugawa T, Hakata T, Yoshizawa A, Kita T, Kishimoto Y, Kimura S, Sakurai A, Kosugi D, Fujita H, Okamoto K, Ueda Y, Fujii T, Taura D, Sakane Y, Yasoda A, Inagaki N.
Transcriptomic landscape of hyperthyroidism in mice overexpressing thyroid-stimulating hormone.
iScience. 2024 Dec 10;28(1):111565. doi: 10.1016/j.isci.2024.111565. eCollection 2025 Jan 17.
90 Ohtsuki T, Sato I, Takashita R, Kodama S, Ikemura K, Opoku G, Watanabe S, Furumatsu T, Yamada H, Ando M, Akiyoshi K, Nishida K, Hirohata S.
Distribution and Incorporation of Extracellular Vesicles into Chondrocytes and Synoviocytes.
Int J Mol Sci. 2024 Nov 6;25(22):11942. doi: 10.3390/ijms252211942.
91 Takahashi M, Yamamoto S, Yamamoto S, Okubo A, Nakagawa Y, Kuwahara K, Matsusaka T, Fukuma S, Yamamoto M, Matsuda M, Yanagita M.
ATP dynamics as a predictor of future podocyte structure and function after acute ischemic kidney injury in female mice.
Nat Commun. 2024 Nov 22;15(1):9977. doi: 10.1038/s41467-024-54222-0.
92 Yamaoka Y, Nishina R, Fujita KI, Takasu K.
Synthetic Study towards Providencin: Stereocontrolled Synthesis of the Furan-Substituted Cyclobutanol Segment.
Chem Pharm Bull (Tokyo). 2024;72(11):966-969. doi: 10.1248/cpb.c24-00629.
93 Iwano M, Suetsugu N, Nishihama R, Ishida S, Horie T, Costa A, Katsuno T, Kimura M, Iida K, Iida H, Nagai T, Kohchi T.
MID1-COMPLEMENTING ACTIVITY regulates cell proliferation and development via Ca2+ signaling in Marchantia polymorpha.
Plant Physiol. 2024 Dec 23;197(1):kiae613. doi: 10.1093/plphys/kiae613.
94 Hirano A, Sakashita A, Fujii W, Baßler K, Tsuji T, Kadoya M, Omoto A, Hiraoka N, Imabayashi T, Kaneko Y, Sofue H, Maehara Y, Seno T, Wada M, Kohno M, Fukuda W, Yamada K, Takayama K, Kawahito Y.
Immunological characteristics of bronchoalveolar lavage fluid and blood across connective tissue disease-associated interstitial lung diseases.
Front Immunol. 2024 Oct 25;15:1408880. doi: 10.3389/fimmu.2024.1408880. eCollection 2024.
95 Takagi M, Nagatani A, Kawano K, Hata A, Yokoyama A, Hayashida K, Hoshi H, Sakurai M, Oyama T, Kuroda Y, Yamaoka Y, Fujiwara T, Miyanoiri Y, Hoshino M, Yano Y, Takasu K, Matsuzaki K.
Stable and Minimum Size Solubilization of Membrane Proteins with Cocktails of Phospholipid Analogues.
ACS Appl Mater Interfaces. 2024 Nov 20;16(46):63358-63367. doi: 10.1021/acsami.4c15697. Epub 2024 Nov 7.
96 Yamashita S, Ueda H, Shirakawa H.
[Important role of relationship between brain and spleen in the mechanisms of chronic pain development and maintenance in fibromyalgia].
Nihon Yakurigaku Zasshi. 2024;159(6):357-362. doi: 10.1254/fpj.24052.
97 Shionoya K, Park JH, Ekimoto T, Takeuchi JS, Mifune J, Morita T, Ishimoto N, Umezawa H, Yamamoto K, Kobayashi C, Kusunoki A, Nomura N, Iwata S, Muramatsu M, Tame JRH, Ikeguchi M, Park SY, Watashi K.
Structural basis for hepatitis B virus restriction by a viral receptor homologue.
Nat Commun. 2024 Oct 25;15(1):9241. doi: 10.1038/s41467-024-53533-6.
98 Miyake T, Tanaka K, Inoue Y, Nagai Y, Nishimura R, Seta T, Nakagawa S, Inoue KI, Hasegawa E, Minamimoto T, Doi M.
Size-reduced DREADD derivatives for AAV-assisted multimodal chemogenetic control of neuronal activity and behavior.
Cell Rep Methods. 2024 Oct 21;4(10):100881. doi: 10.1016/j.crmeth.2024.100881.
99 Ishizaka Y, Watanabe H, Ono M.
Structure-Affinity-Pharmacokinetics Relationships of Novel (18)F-Labeled 1,4-Diazepane Derivatives for Orexin 1 Receptor Imaging.
J Med Chem. 2024 Nov 14;67(21):18781-18793. doi: 10.1021/acs.jmedchem.4c01090. Epub 2024 Oct 21.
100 Takasaki R, Ito E, Nagae M, Takahashi Y, Matsuoka T, Yasue W, Arichi N, Ohno H, Yamasaki S, Inuki S.
Development of Ribityllumazine Analogue as Mucosal-Associated Invariant T Cell Ligands.
J Am Chem Soc. 2024 Oct 30;146(43):29964-29976. doi: 10.1021/jacs.4c12997. Epub 2024 Oct 21.
101 Kuroda Y, Saito H, Tawatari T, Takasu K. Photo-Induced Pyridylic C(sp3)–H Alkylation with Unactivated Alkenes Enabled by Hydrogen Atom Transfer/Lewis Acid Cocatalysis. ACS Catal. 2024 Oct 18;14(20):15036–42. doi:10.1021/acscatal.4c05026
102 Tsuruta H, Yamazaki H, Maeda R, Tamura R, Imura A. A SARS-CoV-2 Interaction Dataset and VHH Sequence Corpus for Antibody Language Models [Internet]. arXiv; 2024 [cited 2026 Mar 5]. Available from: http://arxiv.org/abs/2405.18749 doi:10.48550/arXiv.2405.18749
103 Akasaka T, Watanabe H, Ono M. Combined strategies for optimizing BODIPY-based near-infrared fluorescent probe targeting Aβ oligomers. Sensors and Actuators B: Chemical. 2024 Oct 15;417:136132. doi:10.1016/j.snb.2024.136132
104 Nakano D, Watanabe H, Kosuke S, Ono M.
A Novel Bifunctional Chelating Agent for Tyrosine-Specific Radiolabeling of Peptides and Proteins.
Bioconjug Chem. 2024 Oct 7. doi: 10.1021/acs.bioconjchem.4c00363. Online ahead of print.
105 Horie M, Akiyama Y, Katoh H, Taguchi S, Nakamura M, Mizuguchi K, Ito Y, Matsushita T, Ushiku T, Ishikawa S, Goto A, Kume H, Homma Y, Maeda D.
APRIL/BAFF upregulation is associated with clonal B-cell expansion in Hunner-type interstitial cystitis.
J Pathol. 2024 Dec;264(4):383-395. doi: 10.1002/path.6353. Epub 2024 Oct 3.
106 Yamaguchi K, Kazuta N, Tsuchihashi S, Watanabe H, Ono M.
Structure-affinity-pharmacokinetics relationships of (111)In-labeled PSMA-targeted ligands with different albumin binders.
Nucl Med Biol. 2024 Nov-Dec;138-139:108945. doi: 10.1016/j.nucmedbio.2024.108945. Epub 2024 Aug 3.
107 Koyanagi M, Ogido R, Moriya A, Saigo M, Ihida S, Teranishi T, Kawada J, Katsuno T, Matsubara K, Terada T, Yamashita A, Imai S.
Development of a 3-dimensional organotypic model with characteristics of peripheral sensory nerves.
Cell Rep Methods. 2024 Aug 19;4(8):100835. doi: 10.1016/j.crmeth.2024.100835. Epub 2024 Aug 7.
108 Kakae M, Kawashita A, Onogi H, Nakagawa T, Shirakawa H.
Bilateral Common Carotid Artery Stenosis in Mice: A Model of Chronic Cerebral Hypoperfusion-Induced Vascular Cognitive Impairment.
Bio Protoc. 2024 Jul 5;14(13):e5022. doi: 10.21769/BioProtoc.5022. eCollection 2024 Jul 5.
109 Yamamoto S, Yamamoto S, Takahashi M, Mii A, Okubo A, Toriu N, Nakagawa S, Abe T, Fukuma S, Imamura H, Yamamoto M, Yanagita M.
Visualization of intracellular ATP dynamics in different nephron segments under pathophysiological conditions using the kidney slice culture system.
Kidney Int. 2024 Sep;106(3):470-481. doi: 10.1016/j.kint.2024.05.028. Epub 2024 Jul 9.
110 Kato N, Seki Y, Nanjo T, Takemoto Y.
Bulky Alkyl Substituents Enhance the Photocatalytic Activity of Pyridine-Based Donor-Acceptor Molecules in the Direct Reductive Cleavage of the C-Br Bond of Aliphatic Bromides.
Org Lett. 2024 Jul 19;26(28):5883-5887. doi: 10.1021/acs.orglett.4c01613. Epub 2024 Jul 5.
111 Hashimoto N, Taguchi J, Kasagi T, Arichi N, Inuki S, Ohno H.
Construction of the Akuammiline Alkaloid Core Structure via Stereoselective E-Ring Formation.
J Org Chem. 2024 Jul 19;89(14):10388-10392. doi: 10.1021/acs.joc.4c01105. Epub 2024 Jul 2.
112 Arichi N, Amano T, Wu S, Inuki S, Ohno H.
Synthesis of Sulfilimines via Visible-Light-Mediated Triplet Energy Transfer to Sulfonyl Azides.
Chemistry. 2024 Aug 27;30(48):e202401842. doi: 10.1002/chem.202401842. Epub 2024 Aug 6.
113 Kurokawa K, Ogawa N, Kuroda Y, Yamaoka Y, Takikawa H, Tsubaki K, Takasu K.
Chromic properties of dibenzo[j,l]fluoranthenes exhibiting different resonance contributions.
Org Biomol Chem. 2024 Jul 3;22(26):5306-5313. doi: 10.1039/d4ob00750f.
114 Hagiyama M, Yoneshige A, Wada A, Kimura R, Ito S, Inoue T, Takeuchi F, Ito A.
Efficient intracellular drug delivery by co-administration of two antibodies against cell adhesion molecule 1.
J Control Release. 2024 Jul;371:603-618. doi: 10.1016/j.jconrel.2024.05.035. Epub 2024 Jun 12.
115 Watanuki S, Kobayashi H, Sugiura Y, Yamamoto M, Karigane D, Shiroshita K, Sorimachi Y, Morikawa T, Fujita S, Shide K, Haraguchi M, Tamaki S, Mikawa T, Kondoh H, Nakano H, Sumiyama K, Nagamatsu G, Goda N, Okamoto S, Nakamura-Ishizu A, Shimoda K, Suematsu M, Suda T, Takubo K.
SDHAF1 confers metabolic resilience to aging hematopoietic stem cells by promoting mitochondrial ATP production.
Cell Stem Cell. 2024 Aug 1;31(8):1145-1161.e15. doi: 10.1016/j.stem.2024.04.023. Epub 2024 May 20.
116 Kitadokoro J, Kamitani S, Okuno Y, Hikima T, Yamamoto M, Hirokawa T, Kitadokoro K.
Crystal structure of Staphylococcus aureus lipase complex with unsaturated petroselinic acid.
FEBS Open Bio. 2024 Jun;14(6):942-954. doi: 10.1002/2211-5463.13808. Epub 2024 May 16.
117 Nagashima K, Watanabe H, Akasaka T, Ono M.
Development of Triphenylmethane Dyes for In Vivo Fluorescence Imaging of Aβ Oligomers.
ACS Chem Neurosci. 2024 Jun 5;15(11):2233-2242. doi: 10.1021/acschemneuro.4c00053. Epub 2024 May 16.
118 Takeshita N, Sakaki S, Saba R, Inoue S, Nishikawa K, Ueyama A, Nakajima Y, Matsuo K, Shigeta M, Kobayashi D, Yamazaki H, Yamada K, Iehara T, Yashiro K.
Acto3D: an open-source user-friendly volume rendering software for high-resolution 3D fluorescence imaging in biology.
Development. 2024 Apr 15;151(8):dev202550. doi: 10.1242/dev.202550. Epub 2024 Apr 25.
119 Inuki S, Miyamoto J, Hashimoto N, Shimizu H, Tabuchi H, Kawai A, Greiner LC, Kimura I, Ohno H.
Structure-activity relationship studies of tetrahydroquinolone derivatives as GPR41 modulators.
Bioorg Med Chem Lett. 2024 Jul 15;107:129758. doi: 10.1016/j.bmcl.2024.129758. Epub 2024 Apr 17.
120 Tsuchihashi S, Nakashima K, Watanabe H, Ono M.
Synthesis and evaluation of novel trifunctional chelating agents for pretargeting approach using albumin binder to improve tumor accumulation.
Nucl Med Biol. 2024 May-Jun;132-133:108911. doi: 10.1016/j.nucmedbio.2024.108911. Epub 2024 Apr 5.
121 Murayama S, Ishimoto T, Naka H. Inverse kinetic isotope effect in singlet-to-triplet intersystem crossing contributes to greater robustness of deuterated organocatalyst. bull Chem Soc Jpn. 2024 Apr 1;97(4):uoae028. doi:10.1093/bulcsj/uoae028
122 Masui A, Hashimoto R, Matsumura Y, Yamamoto T, Nagao M, Noda T, Takayama K, Gotoh S.
Micro-patterned culture of iPSC-derived alveolar and airway cells distinguishes SARS-CoV-2 variants.
Stem Cell Reports. 2024 Apr 9;19(4):545-561. doi: 10.1016/j.stemcr.2024.02.011. Epub 2024 Mar 28.
123 Ohnishi Y, Masui A, Suezawa T, Mikawa R, Hirai T, Hagiwara M, Gotoh S.
Screening of factors inducing alveolar type 1 epithelial cells using human pluripotent stem cells.
Stem Cell Reports. 2024 Apr 9;19(4):529-544. doi: 10.1016/j.stemcr.2024.02.009. Epub 2024 Mar 28.
124 Yokoyama T, Manita S, Uwamori H, Tajiri M, Imayoshi I, Yagishita S, Murayama M, Kitamura K, Sakamoto M.
A multicolor suite for deciphering population coding of calcium and cAMP in vivo.
Nat Methods. 2024 May;21(5):897-907. doi: 10.1038/s41592-024-02222-9. Epub 2024 Mar 21.
125 Wang Z, Numada A, Wagai F, Oda Y, Ohgushi M, Maki K, Adachi T, Eiraku M.
Spatial cell fate manipulation of human pluripotent stem cells by controlling the microenvironment using photocurable hydrogel.
Development. 2024 Mar 15;151(6):dev201621. doi: 10.1242/dev.201621. Epub 2024 Mar 21.
126 Hayashi S, Takasu K, Takikawa H. Sequential Bromination/Dearomatization Reactions of 2-Methoxyphenols en route to Bromo-Substituted ortho-Quinonemonoacetals. Synlett. 2024 Mar;35(4):474–8. doi:10.1055/s-0041-1738450
127 Kitano M, Hayashi Y, Ohnishi H, Okuyama H, Yoshimatsu M, Mizuno K, Kuwata F, Tada T, Kishimoto Y, Morita S, Omori K.
Changes in the Proportion of Each Cell Type After hiPSC-Derived Airway Epithelia Transplantation.
Cell Transplant. 2024 Jan-Dec;33:9636897241228026. doi: 10.1177/09636897241228026.
128 Yamaguchi A, Obiya N, Arichi N, Oishi S, Ohno H, Inuki S.
Synthesis of labionin and avionin precursors via a nitrogen-centred-radical-triggered 1,5-HAT reaction of Tris derivatives.
Org Biomol Chem. 2024 Mar 6;22(10):2049-2055. doi: 10.1039/d3ob02037a.
129 Seto Y, Ogihara R, Takizawa K, Eiraku M.
In vitro induction of patterned branchial arch-like aggregate from human pluripotent stem cells.
Nat Commun. 2024 Feb 14;15(1):1351. doi: 10.1038/s41467-024-45285-0.
130 Tamura T, Irie T, Deguchi S, Yajima H, Tsuda M, Nasser H, Mizuma K, Plianchaisuk A, Suzuki S, Uriu K, Begum MM, Shimizu R, Jonathan M, Suzuki R, Kondo T, Ito H, Kamiyama A, Yoshimatsu K, Shofa M, Hashimoto R, Anraku Y, Kimura KT, Kita S, Sasaki J, Sasaki-Tabata K, Maenaka K, Nao N, Wang L, Oda Y; Genotype to Phenotype Japan (G2P-Japan) Consortium; Ikeda T, Saito A, Matsuno K, Ito J, Tanaka S, Sato K, Hashiguchi T, Takayama K, Fukuhara T.
Virological characteristics of the SARS-CoV-2 Omicron XBB.1.5 variant.
Nat Commun. 2024 Feb 8;15(1):1176. doi: 10.1038/s41467-024-45274-3.
131 Umemura K, Kawamoto Y, Takahashi Y, Takakura Y.
Development of a Cytosolic DNA Sensor Agonist Using GALA Peptide-Conjugated DNA and Long Single-Stranded DNA.
Mol Pharm. 2024 Mar 4;21(3):1204-1213. doi: 10.1021/acs.molpharmaceut.3c00840. Epub 2024 Feb 6.
132 Sato Y, Hayashi MT.
Micronucleus is not a potent inducer of the cGAS/STING pathway.
Life Sci Alliance. 2024 Feb 2;7(4):e202302424. doi: 10.26508/lsa.202302424. Print 2024 Apr.
133 Bao H, Sun R, Iwano M, Yoshitake Y, Aki SS, Umeda M, Nishihama R, Yamaoka S, Kohchi T.
Conserved CKI1-mediated signaling is required for female germline specification in Marchantia polymorpha.
Curr Biol. 2024 Mar 25;34(6):1324-1332.e6. doi: 10.1016/j.cub.2024.01.013. Epub 2024 Jan 30.
134 Kita N, Hamamoto A, Gowda SGB, Takatsu H, Nakayama K, Arita M, Hui SP, Shin HW.
Glucosylceramide flippases contribute to cellular glucosylceramide homeostasis.
J Lipid Res. 2024 Mar;65(3):100508. doi: 10.1016/j.jlr.2024.100508. Epub 2024 Jan 26.
135 Zhang H, Ishii K, Shibata T, Ishii S, Hirao M, Lu Z, Takamura R, Kitano S, Miyachi H, Kageyama R, Itakura E, Kobayashi T.
Fluctuation of lysosomal protein degradation in neural stem cells of the postnatal mouse brain.
Development. 2024 Feb 15;151(4):dev202231. doi: 10.1242/dev.202231. Epub 2024 Feb 14.
136 Wang Y, Tamori Y.
Polyploid Cancer Cell Models in Drosophila.
Genes (Basel). 2024 Jan 14;15(1):96. doi: 10.3390/genes15010096.
137 Kuroda Y, Krell M, Kurokawa K, Takasu K.
Synthesis of mesoionic triazolones via a formal [3+2] cycloaddition between 4-phenyl-1,2,4-triazoline-3,5-dione and alkynes.
Chem Commun (Camb). 2024 Feb 8;60(13):1719-1722. doi: 10.1039/d3cc05088b.
138 Asami J, Park JH, Nomura Y, Kobayashi C, Mifune J, Ishimoto N, Uemura T, Liu K, Sato Y, Zhang Z, Muramatsu M, Wakita T, Drew D, Iwata S, Shimizu T, Watashi K, Park SY, Nomura N, Ohto U.
Structural basis of hepatitis B virus receptor binding.
Nat Struct Mol Biol. 2024 Mar;31(3):447-454. doi: 10.1038/s41594-023-01191-5. Epub 2024 Jan 17.
139 Kitamura D, Taniguchi K, Nakamura M, Igaki T.
In vivo evidence for homeostatic regulation of ribosomal protein levels in Drosophila.
Cell Struct Funct. 2024 Feb 16;49(1):11-20. doi: 10.1247/csf.23088. Epub 2024 Jan 11.
140 Imamura K, Akagi KI, Miyanoiri Y, Tsujimoto H, Hirokawa T, Ashida H, Murakami K, Inoue A, Suno R, Ikegami T, Sekiyama N, Iwata S, Kobayashi T, Tochio H.
Interaction modes of human orexin 2 receptor with selective and nonselective antagonists studied by NMR spectroscopy.
Structure. 2024 Mar 7;32(3):352-361.e5. doi: 10.1016/j.str.2023.12.008. Epub 2024 Jan 8.
141 Ohara D, Takeuchi Y, Watanabe H, Lee Y, Mukoyama H, Ohteki T, Kondoh G, Hirota K.
Notch2 with retinoic acid license IL-23 expression by intestinal EpCAM+ DCIR2+ cDC2s in mice.
J Exp Med. 2024 Feb 5;221(2):e20230923. doi: 10.1084/jem.20230923. Epub 2024 Jan 5.
142 Kagoshima H, Ohnishi H, Yamamoto R, Yasumoto A, Tona Y, Nakagawa T, Omori K, Yamamoto N.
EBF1 Limits the Numbers of Cochlear Hair and Supporting Cells and Forms the Scala Tympani and Spiral Limbus during Inner Ear Development.
J Neurosci. 2024 Feb 14;44(7):e1060232023. doi: 10.1523/JNEUROSCI.1060-23.2023.
143 Kajiwara T, Miyazaki M, Yamaoka S, Yoshitake Y, Yasui Y, Nishihama R, Kohchi T.
Transcription of the Antisense Long Non-Coding RNA, SUPPRESSOR OF FEMINIZATION, Represses Expression of the Female-Promoting Gene FEMALE GAMETOPHYTE MYB in the Liverwort Marchantia polymorpha.
Plant Cell Physiol. 2024 Apr 16;65(3):338-349. doi: 10.1093/pcp/pcad170.
144 Tsuji S, Otani C, Horie T, Watanabe S, Baba O, Sowa N, Ide Y, Kashiwa A, Makiyama T, Imai H, Nakashima Y, Yamasaki T, Xu S, Matsushita K, Suzuki K, Zou F, Kume E, Hasegawa K, Kimura T, Kakizuka A, Ono K.
KUS121, a VCP modulator, has an ameliorating effect on acute and chronic heart failure without calcium loading via maintenance of intracellular ATP levels.
Biomed Pharmacother. 2024 Jan;170:115850. doi: 10.1016/j.biopha.2023.115850. Epub 2023 Dec 12.
145 Hamamoto A, Kita N, B Gowda SG, Takatsu H, Nakayama K, Arita M, Hui SP, Shin HW.
Lysosomal membrane integrity in fibroblasts derived from patients with Gaucher disease.
Cell Struct Funct. 2024 Jan 23;49(1):1-10. doi: 10.1247/csf.23066. Epub 2023 Dec 9.
146 Yoshimoto K, Maki K, Adachi T, Kamei KI.
Cyclic Stretching Enhances Angiocrine Signals at Liver Bud Stage from Human Pluripotent Stem Cells in Two-Dimensional Culture.
Tissue Eng Part A. 2024 May;30(9-10):426-439. doi: 10.1089/ten.TEA.2023.0148. Epub 2024 Jan 10.
147 Hayashi Y, Ohnishi H, Kitano M, Kishimoto Y, Takezawa T, Okuyama H, Yoshimatsu M, Kuwata F, Tada T, Mizuno K, Omori K.
Comparative Study of Immunodeficient Rat Strains in Engraftment of Human-Induced Pluripotent Stem Cell-Derived Airway Epithelia.
Tissue Eng Part A. 2024 Feb;30(3-4):144-153. doi: 10.1089/ten.TEA.2023.0214. Epub 2023 Dec 20.
148 Aoki K, Hyuga M, Tarumoto Y, Nishibuchi G, Ueda A, Ochi Y, Sugino S, Mikami T, Kobushi H, Kato I, Akahane K, Inukai T, Takaori-Kondo A, Takita J, Ogawa S, Yusa K.
Canonical BAF complex regulates the oncogenic program in human T-cell acute lymphoblastic leukemia.
Blood. 2024 Feb 15;143(7):604-618. doi: 10.1182/blood.2023020857.
149 Uehata T, Yamada S, Ori D, Vandenbon A, Giladi A, Jelinski A, Murakawa Y, Watanabe H, Takeuchi K, Toratani K, Mino T, Kiryu H, Standley DM, Tsujimura T, Ikawa T, Kondoh G, Landthaler M, Kawamoto H, Rodewald HR, Amit I, Yamamoto R, Miyazaki M, Takeuchi O.
Regulation of lymphoid-myeloid lineage bias through regnase-1/3-mediated control of Nfkbiz.
Blood. 2024 Jan 18;143(3):243-257. doi: 10.1182/blood.2023020903.
150 Nishida Y, Shirakashi M, Hashii N, Nakashima R, Nakayama Y, Katsushima M, Watanabe R, Onizawa H, Hiwa R, Tsuji H, Kitagori K, Akizuki S, Onishi A, Murakami K, Yoshifuji H, Tanaka M, Tsuruyama T, Morinobu A, Hashimoto M.
Pathogenicity of IgG-Fc desialylation and its association with Th17 cells in an animal model of systemic lupus erythematosus.
Mod Rheumatol. 2024 Mar 28;34(3):523-529. doi: 10.1093/mr/road054.
151 Yoshida Y, Takeuchi H, Arichi N, Oishi S, Ohno H, Inuki S. Approach to Spirocyclohexadienes via Visible Light-Mediated ipso-Cyclization of Amino Acid Derivatives with N-(2-Phenyl)benzoyl Groups. Asian Journal of Organic Chemistry. 2024;13(7):e202400140. doi:10.1002/ajoc.202400140
152 中寛史. 触媒と反応場の制御による官能基選択的な水和反応の開拓. 有機合成化学協会誌. 2024;82(1):14–26. doi:10.5059/yukigoseikyokaishi.82.14
153 Ishikawa M, Sugino S, Masuda Y, Tarumoto Y, Seto Y, Taniyama N, Wagai F, Yamauchi Y, Kojima Y, Kiryu H, Yusa K, Eiraku M, Mochizuki A.
RENGE infers gene regulatory networks using time-series single-cell RNA-seq data with CRISPR perturbations.
Commun Biol. 2023 Dec 28;6(1):1290. doi: 10.1038/s42003-023-05594-4.
154 Mure A, Sugiura Y, Maeda R, Honda K, Sakurai N, Takahashi Y, et al. Identification of key yeast species and microbe–microbe interactions impacting larval growth of Drosophila in the wild. Antunes C, Cardona A, editors. eLife. 2023 Dec 27;12:RP90148. doi:10.7554/eLife.90148
155 Hashimoto N, Taguchi J, Arichi N, Inuki S, Ohno H.
Gold(I)-Catalyzed Cascade Cyclization of Alkynyl Indoles for the Stereoselective Construction of the Quaternary Carbon Center of Akuammiline Alkaloids.
J Org Chem. 2023 Dec 15;88(24):17306-17321. doi: 10.1021/acs.joc.3c02142. Epub 2023 Dec 5.
156 Zhao Z, Ito A, Kuroki H, Aoyama T.
Analysis of Molecular Changes and Features in Rat Knee Osteoarthritis Cartilage: Progress From Cellular Changes to Structural Damage.
Cartilage. 2023 Nov 17:19476035231213174. doi: 10.1177/19476035231213174. Online ahead of print.
157 Wei H, Naruse C, Takakura D, Sugihara K, Pan X, Ikeda A, Kawasaki N, Asano M.
Beta-1,4-galactosyltransferase-3 deficiency suppresses the growth of immunogenic tumors in mice.
Front Immunol. 2023 Oct 9;14:1272537. doi: 10.3389/fimmu.2023.1272537. eCollection 2023.
158 Imamura H, Otsubo S, Nishida M, Takekawa N, Imada K.
Red fluorescent proteins engineered from green fluorescent proteins.
Proc Natl Acad Sci U S A. 2023 Nov 7;120(45):e2307687120. doi: 10.1073/pnas.2307687120. Epub 2023 Oct 23.
159 Onoue R, Watanabe H, Ono M.
Synthesis and biological evaluation of bi-modal BODIPY-conjugated Hoechst applicable for Auger-electron and photodynamic cancer therapy.
Bioorg Med Chem Lett. 2023 Nov 15;96:129534. doi: 10.1016/j.bmcl.2023.129534. Epub 2023 Oct 20.
160 Ito S, Kuromiya K, Sekai M, Sako H, Sai K, Morikawa R, Mukai Y, Ida Y, Anzai M, Ishikawa S, Kozawa K, Shirai T, Tanimura N, Sugie K, Ikenouchi J, Ogawa M, Naguro I, Ichijo H, Fujita Y.
Accumulation of annexin A2 and S100A10 prevents apoptosis of apically delaminated, transformed epithelial cells.
Proc Natl Acad Sci U S A. 2023 Oct 24;120(43):e2307118120. doi: 10.1073/pnas.2307118120. Epub 2023 Oct 16.
161 Akasaka T, Watanabe H, Ono M.
In Vivo Near-Infrared Fluorescence Imaging Selective for Soluble Amyloid β Aggregates Using y-Shaped BODIPY Derivative.
J Med Chem. 2023 Oct 26;66(20):14029-14046. doi: 10.1021/acs.jmedchem.3c01057. Epub 2023 Oct 12.
162 Tsuruta H, Yamazaki H, Maeda R, Tamura R, Wei JN, Mariet Z, et al. AVIDa-hIL6: A Large-Scale VHH Dataset Produced from an Immunized Alpaca for Predicting Antigen-Antibody Interactions [Internet]. arXiv; 2023 [cited 2026 Mar 5]. Available from: http://arxiv.org/abs/2306.03329 doi:10.48550/arXiv.2306.03329
163 Miyata Y, Nishida E.
Identification of FAM53C as a cytosolic-anchoring inhibitory binding protein of the kinase DYRK1A.
Life Sci Alliance. 2023 Oct 6;6(12):e202302129. doi: 10.26508/lsa.202302129. Print 2023 Dec.
164 Yumura T, Nanjo T, Takemoto Y. A Benzophenothiazine/Boronic Acid Hybrid Photocatalyst Enables the Single Electron Transfer (SET) to Carboxy Groups: SET-Initiated Cyclization of α,β-Unsaturated Carboxylic Acids. ACS Catal. 2023 Oct 6;13(19):12803–9. doi:10.1021/acscatal.3c03662
165 Kitada Y, Ohnishi H, Yamamoto N, Kuwata F, Kitano M, Mizuno K, Omori K.
Transplantation of Induced Pluripotent Stem Cell-Derived Airway Epithelia with a Collagen Scaffold into the Nasal Cavity.
Tissue Eng Part C Methods. 2023 Nov;29(11):526-534. doi: 10.1089/ten.TEC.2023.0074. Epub 2023 Oct 18.
166 Omatsu M, Nakanishi Y, Iwane K, Aoyama N, Duran A, Muta Y, Martinez-Ordoñez A, Han Q, Agatsuma N, Mizukoshi K, Kawai M, Yamakawa G, Namikawa M, Hamada K, Fukunaga Y, Utsumi T, Sono M, Masuda T, Hata A, Araki O, Nagao M, Yoshikawa T, Ogawa S, Hiramatsu Y, Tsuda M, Maruno T, Kogame T, Kasashima H, Kakiuchi N, Nakagawa MM, Kawada K, Yashiro M, Maeda K, Saito Y, Matozaki T, Fukuda A, Kabashima K, Obama K, Ogawa S, Sheibani N, Diaz-Meco MT, Moscat J, Seno H.
THBS1-producing tumor-infiltrating monocyte-like cells contribute to immunosuppression and metastasis in colorectal cancer.
Nat Commun. 2023 Sep 25;14(1):5534. doi: 10.1038/s41467-023-41095-y.
167 Oda W, Umemura K, Ito K, Kawamoto Y, Takahashi Y, Takakura Y.
Development of potent unmethylated CpG DNA hydrogel by introducing i-motifs into long single-stranded DNA.
Int J Pharm. 2023 Nov 5;646:123438. doi: 10.1016/j.ijpharm.2023.123438. Epub 2023 Sep 22.
168 Nguyen Vu TH, Kikuchi O, Ohashi S, Saito T, Ida T, Nakai Y, Cao Y, Yamamoto Y, Kondo Y, Mitani Y, Kataoka S, Kondo T, Katada C, Yamada A, Matsubara J, Muto M.
Combination therapy with WEE1 inhibition and trifluridine/tipiracil against esophageal squamous cell carcinoma.
Cancer Sci. 2023 Dec;114(12):4664-4676. doi: 10.1111/cas.15966. Epub 2023 Sep 19.
169 Matsuoka T, Hattori A, Oishi S, Araki M, Ma B, Fujii T, et al. Establishment of an MR1 Presentation Reporter Screening System and Identification of Phenylpropanoid Derivatives as MR1 Ligands. J Med Chem. 2023 Sep 14;66(17):12520–35. doi:10.1021/acs.jmedchem.3c01122
170 Bao H, Sun R, Iwano M, Yoshitake Y, Aki SS, Umeda M, et al. Evolutionarily Conserved CKI1-Mediated Two-Component Signaling is Required for Female Germline Specification in Marchantia polymorpha [Internet]. bioRxiv; 2023 [cited 2026 Mar 5]. p. 2023.09.10.556599. Available from: https://www.biorxiv.org/content/10.1101/2023.09.10.556599v1 doi:10.1101/2023.09.10.556599
171 Kato N, Nanjo T, Takemoto Y.
Electron Donor-Acceptor (EDA) Complex between a Triarylamine and B(C(6)F(5))(3) for the Photocatalytic Dehydrogenative Cross-Coupling of Phenols.
Chem Pharm Bull (Tokyo). 2023;71(9):747-750. doi: 10.1248/cpb.c23-00409.
172 Tsuboi A, Fujimoto K, Kondo T.
Spatiotemporal remodeling of extracellular matrix orients epithelial sheet folding.
Sci Adv. 2023 Sep;9(35):eadh2154. doi: 10.1126/sciadv.adh2154. Epub 2023 Sep 1.
173 Ishimura T, Ishii A, Yamada H, Osaki K, Toda N, Mori KP, Ohno S, Kato Y, Handa T, Sugioka S, Ikushima A, Nishio H, Yanagita M, Yokoi H.
Matrix metalloproteinase-10 deficiency has protective effects against peritoneal inflammation and fibrosis via transcription factor NFκΒ pathway inhibition.
Kidney Int. 2023 Nov;104(5):929-942. doi: 10.1016/j.kint.2023.08.010. Epub 2023 Aug 29.
174 Matsuoka T, Hattori A, Oishi S, Araki M, Ma B, Fujii T, Arichi N, Okuno Y, Kakeya H, Yamasaki S, Ohno H, Inuki S.
Establishment of an MR1 Presentation Reporter Screening System and Identification of Phenylpropanoid Derivatives as MR1 Ligands.
J Med Chem. 2023 Sep 14;66(17):12520-12535. doi: 10.1021/acs.jmedchem.3c01122. Epub 2023 Aug 28.
175 Hirose Y, Sato S, Hashiya K, Bando T, Sugiyama H.
Anticancer Activities of DNA-Alkylating Pyrrole-Imidazole Polyamide Analogs Targeting RUNX Transcription Factors against p53-Mutated Pancreatic Cancer PANC-1 Cells.
J Med Chem. 2023 Sep 14;66(17):12059-12068. doi: 10.1021/acs.jmedchem.3c00613. Epub 2023 Aug 22.
176 Sun R, Okabe M, Miyazaki S, Ishida T, Mashiguchi K, Inoue K, Yoshitake Y, Yamaoka S, Nishihama R, Kawaide H, Nakajima M, Yamaguchi S, Kohchi T.
Biosynthesis of gibberellin-related compounds modulates far-red light responses in the liverwort Marchantia polymorpha.
Plant Cell. 2023 Oct 30;35(11):4111-4132. doi: 10.1093/plcell/koad216.
177 Nanjo T, Matsumoto A, Oshita T, Takemoto Y.
Synthesis of Chlorinated Oligopeptides via γ- and δ-Selective Hydrogen Atom Transfer Enabled by the N-Chloropeptide Strategy.
J Am Chem Soc. 2023 Aug 30;145(34):19067-19075. doi: 10.1021/jacs.3c06931. Epub 2023 Aug 18.
178 Oka S, Watanabe M, Ito E, Takeyama A, Matsuoka T, Takahashi M, Izumi Y, Arichi N, Ohno H, Yamasaki S, Inuki S.
Archaeal Glycerolipids Are Recognized by C-Type Lectin Receptor Mincle.
J Am Chem Soc. 2023 Aug 23;145(33):18538-18548. doi: 10.1021/jacs.3c05473. Epub 2023 Aug 9.
179 Bui HB, Watanabe S, Nomura N, Liu K, Uemura T, Inoue M, Tsutsumi A, Fujita H, Kinoshita K, Kato Y, Iwata S, Kikkawa M, Inaba K.
Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn(2+) uptake into the Golgi apparatus.
Nat Commun. 2023 Aug 8;14(1):4770. doi: 10.1038/s41467-023-40521-5.
180 Yoshikawa T, Oguchi A, Toriu N, Sato Y, Kobayashi T, Ogawa O, Haga H, Sakurai S, Yamamoto T, Murakawa Y, Yanagita M.
Tertiary Lymphoid Tissues Are Microenvironments with Intensive Interactions between Immune Cells and Proinflammatory Parenchymal Cells in Aged Kidneys.
J Am Soc Nephrol. 2023 Oct 1;34(10):1687-1708. doi: 10.1681/ASN.0000000000000202. Epub 2023 Aug 7.
181 Kobayashi K, Iwasa K, Azuma-Suzuki R, Kawauchi T, Nabeshima YI.
Feto-maternal cholesterol transport regulated by β-Klotho-FGF15 axis is essential for fetal growth.
Life Sci Alliance. 2023 Aug 4;6(10):e202301916. doi: 10.26508/lsa.202301916. Print 2023 Oct.
182 Sakaguchi S, Mizuno S, Okochi Y, Tanegashima C, Nishimura O, Uemura T, Kadota M, Naoki H, Kondo T.
Single-cell transcriptome atlas of Drosophila gastrula 2.0.
Cell Rep. 2023 Jul 25;42(7):112707. doi: 10.1016/j.celrep.2023.112707. Epub 2023 Jul 10.
183 Tasaki K, Zhou Z, Ishida Y, Katoh Y, Nakayama K.
Compound heterozygous IFT81 variations in a skeletal ciliopathy patient cause Bardet-Biedl syndrome-like ciliary defects.
Hum Mol Genet. 2023 Sep 16;32(19):2887-2900. doi: 10.1093/hmg/ddad112.
184 Tsuno H, Shen J, Komatsu H, Arichi N, Inuki S, Ohno H.
Gold(I)-Catalyzed Bis-Cyclization of Allenynes for the Synthesis of Strained and Planar Polycyclic Compounds.
Angew Chem Int Ed Engl. 2023 Aug 28;62(35):e202307532. doi: 10.1002/anie.202307532. Epub 2023 Jul 18.
185 Pérez-Cabello JA, Silvera-Carrasco L, Franco JM, Capilla-González V, Armaos A, Gómez-Lima M, García-García R, Yap XW, Leal-Lasarte M, Lall D, Baloh RH, Martínez S, Miyata Y, Tartaglia GG, Sawarkar R, García-Domínguez M, Pozo D, Roodveldt C.
MAPK/MAK/MRK overlapping kinase (MOK) controls microglial inflammatory/type-I IFN responses via Brd4 and is involved in ALS.
Proc Natl Acad Sci U S A. 2023 Jul 11;120(28):e2302143120. doi: 10.1073/pnas.2302143120. Epub 2023 Jul 3.
186 Yoshida Y, Takeuchi H, Nakagawa K, Fujii T, Arichi N, Oishi S, Ohno H, Inuki S.
Construction of a Bicyclo[2.2.2]octene Skeleton via a Visible-Light-Mediated Radical Cascade Reaction of Amino Acid Derivatives with N-(2-Phenyl)benzoyl Groups.
Org Lett. 2023 Jul 7;25(26):4846-4851. doi: 10.1021/acs.orglett.3c01586. Epub 2023 Jun 27.
187 Sugioka S, Yamada H, Ishii A, Kato Y, Yamada R, Mori KP, Ohno S, Handa T, Ikushima A, Ishimura T, Osaki K, Tokudome T, Matsusaka T, Nebreda AR, Yanagita M, Yokoi H.
Dual deletion of guanylyl cyclase-A and p38 mitogen-activated protein kinase in podocytes with aldosterone administration causes glomerular intra-capillary thrombi.
Kidney Int. 2023 Sep;104(3):508-525. doi: 10.1016/j.kint.2023.06.007. Epub 2023 Jun 24.
188 Nakamura T, Nishikawa Y, Shiokawa M, Takeda H, Yokode M, Matsumoto S, Muramoto Y, Ota S, Yoshida H, Okada H, Kuwada T, Marui S, Matsumori T, Maruno T, Uza N, Kodama Y, Hatano E, Seno H.
ELF3 suppresses gallbladder cancer development through downregulation of the EREG/EGFR/mTOR complex 1 signalling pathway.
J Pathol. 2023 Sep;261(1):28-42. doi: 10.1002/path.6144. Epub 2023 Jun 22.
189 Murayama S, Li Z, Liang H, Liu Y, Naka H, Maruoka K.
Impact of Catalyst Deuteration on the Reactivity of Chiral Phase-Transfer Organocatalysts.
Chemistry. 2023 Sep 21;29(53):e202301866. doi: 10.1002/chem.202301866. Epub 2023 Jul 28.
190 Kira A, Tatsutomi I, Saito K, Murata M, Hattori I, Kajita H, Muraki N, Oda Y, Satoh S, Tsukamoto Y, Kimura S, Onoue K, Yonemura S, Arakawa S, Kato H, Hirashima T, Kawane K.
Apoptotic extracellular vesicle formation via local phosphatidylserine exposure drives efficient cell extrusion.
Dev Cell. 2023 Jul 24;58(14):1282-1298.e7. doi: 10.1016/j.devcel.2023.05.008. Epub 2023 Jun 13.
191 Mizuno K, Ohnishi H, Yoshimatsu M, Zhao C, Hayashi Y, Kuwata F, Kaba S, Okuyama H, Kawai Y, Hiwatashi N, Kishimoto Y, Sakamoto T, Ikeya M, Omori K.
Laryngeal Cartilage Regeneration of Nude Rats by Transplantation of Mesenchymal Stem Cells Derived from Human-Induced Pluripotent Stem Cells.
Cell Transplant. 2023 Jan-Dec;32:9636897231178460. doi: 10.1177/09636897231178460.
192 Nishiyama K, Akiba H, Nagata S, Tsumoto K, Kamada H, Ohno H.
A Proximity-Induced Fluorogenic Reaction Triggered by Antibody-Antigen Interactions with Adjacent Epitopes.
Angew Chem Int Ed Engl. 2023 Jul 24;62(30):e202306431. doi: 10.1002/anie.202306431. Epub 2023 Jun 16.
193 Morimoto T, Takemura Y, Miura T, Yamamoto T, Kakizaki F, An H, Maekawa H, Yamaura T, Kawada K, Sakai Y, Yuba Y, Terajima H, Obama K, Taketo MM, Miyoshi H.
Novel and efficient method for culturing patient-derived gastric cancer stem cells.
Cancer Sci. 2023 Aug;114(8):3259-3269. doi: 10.1111/cas.15840. Epub 2023 May 20.
194 Nishio H, Ishii A, Yamada H, Mori KP, Kato Y, Ohno S, Handa T, Sugioka S, Ishimura T, Ikushima A, Inoue Y, Minamino N, Mukoyama M, Yanagita M, Yokoi H.
Sacubitril/valsartan ameliorates renal tubulointerstitial injury through increasing renal plasma flow in a mouse model of type 2 diabetes with aldosterone excess.
Nephrol Dial Transplant. 2023 Oct 31;38(11):2517-2527. doi: 10.1093/ndt/gfad098.
195 Ito J, Suzuki R, Uriu K, Itakura Y, Zahradnik J, Kimura KT, Deguchi S, Wang L, Lytras S, Tamura T, Kida I, Nasser H, Shofa M, Begum MM, Tsuda M, Oda Y, Suzuki T, Sasaki J, Sasaki-Tabata K, Fujita S, Yoshimatsu K, Ito H, Nao N, Asakura H, Nagashima M, Sadamasu K, Yoshimura K, Yamamoto Y, Nagamoto T, Kuramochi J, Schreiber G; Genotype to Phenotype Japan (G2P-Japan) Consortium; Saito A, Matsuno K, Takayama K, Hashiguchi T, Tanaka S, Fukuhara T, Ikeda T, Sato K.
Convergent evolution of SARS-CoV-2 Omicron subvariants leading to the emergence of BQ.1.1 variant.
Nat Commun. 2023 May 11;14(1):2671. doi: 10.1038/s41467-023-38188-z.
196 Murakami S, Brudy C, Bachmann M, Takemoto Y, Pieber B. Photocatalytic Cleavage of Trityl Protected Thiols and Alcohols. Synthesis. 2023 May;55(09):1367–74. doi:10.1055/a-1979-5933
197 Yoshikawa K, Kato N, Nanjo T, Takemoto Y.
Mechanistic Insight into the TBHP-Mediated Decarboxylative Condensation of α-Ketoacids: Reaction Development and Application to Oligopeptide Synthesis.
Chem Pharm Bull (Tokyo). 2023;71(5):354-359. doi: 10.1248/cpb.c22-00910.
198 Jaunet-Lahary T, Shimamura T, Hayashi M, Nomura N, Hirasawa K, Shimizu T, Yamashita M, Tsutsumi N, Suehiro Y, Kojima K, Sudo Y, Tamura T, Iwanari H, Hamakubo T, Iwata S, Okazaki KI, Hirai T, Yamashita A.
Structure and mechanism of oxalate transporter OxlT in an oxalate-degrading bacterium in the gut microbiota.
Nat Commun. 2023 Apr 3;14(1):1730. doi: 10.1038/s41467-023-36883-5.
199 Tsuchiya M, Tachibana N, Nagao K, Tamura T, Hamachi I.
Organelle-selective click labeling coupled with flow cytometry allows pooled CRISPR screening of genes involved in phosphatidylcholine metabolism.
Cell Metab. 2023 Jun 6;35(6):1072-1083.e9. doi: 10.1016/j.cmet.2023.02.014. Epub 2023 Mar 13.
200 Nagai T, Terada N, Fujii M, Nagata Y, Nakahara K, Mukai S, Okasho K, Kamiyama Y, Akamatsu S, Kobayashi T, Iida K, Denawa M, Hagiwara M, Inoue T, Ogawa O, Kamoto T.
Identification of the α2 chain of interleukin-13 receptor as a potential biomarker for predicting castration resistance of prostate cancer using patient-derived xenograft models.
Cancer Rep (Hoboken). 2023 Feb;6(2):e1701. doi: 10.1002/cnr2.1701. Epub 2022 Aug 9.
201 Tsuji A, Masuya T, Arichi N, Inuki S, Murai M, Miyoshi H, Ohno H.
Discovery of Bis-sulfonamides as Novel Inhibitors of Mitochondrial NADH-Quinone Oxidoreductase (Complex I).
ACS Med Chem Lett. 2023 Jan 24;14(2):211-216. doi: 10.1021/acsmedchemlett.2c00504. eCollection 2023 Feb 9.
202 Kanaoka Y, Onodera K, Watanabe K, Hayashi Y, Usui T, Uemura T, Hattori Y.
Inter-organ Wingless/Ror/Akt signaling regulates nutrient-dependent hyperarborization of somatosensory neurons.
Elife. 2023 Jan 17;12:e79461. doi: 10.7554/eLife.79461.
203 Najnin RA, Al Mahmud MR, Rahman MM, Takeda S, Sasanuma H, Tanaka H, Murakawa Y, Shimizu N, Akter S, Takagi M, Sunada T, Akamatsu S, He G, Itou J, Toi M, Miyaji M, Tsutsui KM, Keeney S, Yamada S.
ATM suppresses c-Myc overexpression in the mammary epithelium in response to estrogen.
Cell Rep. 2023 Jan 31;42(1):111909. doi: 10.1016/j.celrep.2022.111909. Epub 2022 Dec 30.
204 Wu P, Asada H, Hakamada M, Mabuchi M.
Bioengineering of High Cell Density Tissues with Hierarchical Vascular Networks for Ex Vivo Whole Organs.
Adv Mater. 2023 Mar;35(9):e2209149. doi: 10.1002/adma.202209149. Epub 2023 Jan 1.
205 Takase Y, Shirakashi M, Nishida Y, Katsushima M, Onizawa H, Hiwa R, Tsuji H, Kitagori K, Akizuki S, Onishi A, Nakashima R, Murakami K, Yoshifuji H, Tanaka M, Tsuruyama T, Morinobu A, Hashimoto M.
Enteric Toll-like receptor 7 stimulation causes acute exacerbation in lupus-susceptible mice.
Clin Rheumatol. 2023 Apr;42(4):1185-1194. doi: 10.1007/s10067-022-06467-7. Epub 2022 Dec 14.
206 Ishikawa H, Menju T, Toyazaki T, Miyamoto H, Chiba N, Noguchi M, Tamari S, Miyata R, Yutaka Y, Tanaka S, Yamada Y, Nakajima D, Ohsumi A, Hamaji M, Okuno Y, Date H.
A novel cell-based assay for the high-throughput screening of epithelial-mesenchymal transition inhibitors: Identification of approved and investigational drugs that inhibit epithelial-mesenchymal transition.
Lung Cancer. 2023 Jan;175:36-46. doi: 10.1016/j.lungcan.2022.11.015. Epub 2022 Nov 23.
207 Akter S, Shimba A, Ikuta K, Mahmud MRA, Yamada S, Sasanuma H, Tsuda M, Sone M, Ago Y, Murai K, Tanaka H, Takeda S.
Physiological concentrations of glucocorticoids induce pathological DNA double-strand breaks.
Genes Cells. 2023 Jan;28(1):53-67. doi: 10.1111/gtc.12993. Epub 2022 Dec 7.
208 Yamaguchi K, Anzai I, Maeda R, Moriguchi M, Watanabe T, Imura A, Takaori-Kondo A, Inoue T.
Structural insights into the rational design of a nanobody that binds with high affinity to the SARS-CoV-2 spike variant.
J Biochem. 2023 Feb 3;173(2):115-127. doi: 10.1093/jb/mvac096.
209 Greiner LC, Arichi N, Inuki S, Ohno H.
Gold(I)-Catalyzed Benzylic C(sp(3) )-H Functionalizations: Divergent Synthesis of Indole[a]- and [b]-Fused Polycycles.
Angew Chem Int Ed Engl. 2023 Jan 16;62(3):e202213653. doi: 10.1002/anie.202213653. Epub 2022 Dec 8.
210 Greiner LC, Arichi N, Inuki S, Ohno H. Alkoxymigration onto α-Imino Gold Carbenes for Constructing Propellane-Type Indolines. Asian Journal of Organic Chemistry. 2023;12(7):e202300232. doi:10.1002/ajoc.202300232
211 Nanjo T, Sada H, Nagaya T, Maruo Y, Takemoto Y. Rhodium-Catalyzed C−H Alkylation for the Stereoselective Synthesis of β,β-Disubstituted Dehydroamino-Acid Motifs. Asian Journal of Organic Chemistry. 2023;12(7):e202300227. doi:10.1002/ajoc.202300227
212 Murai S, Takakura K, Sumiyama K, Moriwaki K, Terai K, Komazawa-Sakon S, Seki T, Yamaguchi Y, Mikami T, Araki K, Ohmuraya M, Matsuda M, Nakano H.
Generation of transgenic mice expressing a FRET biosensor, SMART, that responds to necroptosis.
Commun Biol. 2022 Dec 5;5(1):1331. doi: 10.1038/s42003-022-04300-0.
213 Matsushima S, Ajiro M, Iida K, Chamoto K, Honjo T, Hagiwara M.
Chemical induction of splice-neoantigens attenuates tumor growth in a preclinical model of colorectal cancer.
Sci Transl Med. 2022 Nov 30;14(673):eabn6056. doi: 10.1126/scitranslmed.abn6056. Epub 2022 Nov 30.
214 Nagata K, Utsumi D, Asaka MN, Maeda R, Shirakawa K, Kazuma Y, Nomura R, Horisawa Y, Yanagida Y, Kawai Y, Sato K, Yamaoka Y, Miyakawa K, Ryo A, Yasutomi Y, Imura A, Takaori-Kondo A.
Intratracheal trimerized nanobody cocktail administration suppresses weight loss and prolongs survival of SARS-CoV-2 infected mice.
Commun Med (Lond). 2022 Nov 26;2(1):152. doi: 10.1038/s43856-022-00213-5.
215 Tamai K, Sakai K, Yamaki H, Moriguchi K, Igura K, Maehana S, Suezawa T, Takehara K, Hagiwara M, Hirai T, Gotoh S.
iPSC-derived mesenchymal cells that support alveolar organoid development.
Cell Rep Methods. 2022 Sep 19;2(10):100314. doi: 10.1016/j.crmeth.2022.100314. eCollection 2022 Oct 24.
216 Yoshinaga M, Han K, Morgens DW, Horii T, Kobayashi R, Tsuruyama T, Hia F, Yasukura S, Kajiya A, Cai T, Cruz PHC, Vandenbon A, Suzuki Y, Kawahara Y, Hatada I, Bassik MC, Takeuchi O.
The N(6)-methyladenosine methyltransferase METTL16 enables erythropoiesis through safeguarding genome integrity.
Nat Commun. 2022 Oct 28;13(1):6435. doi: 10.1038/s41467-022-34078-y.
217 Al-Habsi M, Chamoto K, Matsumoto K, Nomura N, Zhang B, Sugiura Y, Sonomura K, Maharani A, Nakajima Y, Wu Y, Nomura Y, Menzies R, Tajima M, Kitaoka K, Haku Y, Delghandi S, Yurimoto K, Matsuda F, Iwata S, Ogura T, Fagarasan S, Honjo T.
Spermidine activates mitochondrial trifunctional protein and improves antitumor immunity in mice.
Science. 2022 Oct 28;378(6618):eabj3510. doi: 10.1126/science.abj3510. Epub 2022 Oct 28.
218 Nakagawa K, Watanabe H, Kaide S, Ono M.
Structure-Activity Relationships of Styrylquinoline and Styrylquinoxaline Derivatives as α-Synuclein Imaging Probes.
ACS Med Chem Lett. 2022 Sep 26;13(10):1598-1605. doi: 10.1021/acsmedchemlett.2c00279. eCollection 2022 Oct 13.
219 Abe M, Kamiyama T, Izumi Y, Qian Q, Yoshihashi Y, Degawa Y, Watanabe K, Hattori Y, Uemura T, Niwa R.
Shortened lifespan induced by a high-glucose diet is associated with intestinal immune dysfunction in Drosophila sechellia.
J Exp Biol. 2022 Nov 1;225(21):jeb244423. doi: 10.1242/jeb.244423. Epub 2022 Oct 31.
220 Kaide S, Watanabe H, Iikuni S, Hasegawa M, Ono M.
Synthesis and Evaluation of (18)F-Labeled Chalcone Analogue for Detection of α-Synuclein Aggregates in the Brain Using the Mouse Model.
ACS Chem Neurosci. 2022 Oct 19;13(20):2982-2990. doi: 10.1021/acschemneuro.2c00473. Epub 2022 Oct 5.
221 Hino N, Matsuda K, Jikko Y, Maryu G, Sakai K, Imamura R, Tsukiji S, Aoki K, Terai K, Hirashima T, Trepat X, Matsuda M.
A feedback loop between lamellipodial extension and HGF-ERK signaling specifies leader cells during collective cell migration.
Dev Cell. 2022 Oct 10;57(19):2290-2304.e7. doi: 10.1016/j.devcel.2022.09.003. Epub 2022 Sep 28.
222 Fukushima Y, Sakamoto K, Matsuda M, Yoshikai Y, Yagita H, Kitamura D, Chihara M, Minato N, Hattori M.
cis interaction of CD153 with TCR/CD3 is crucial for the pathogenic activation of senescence-associated T cells.
Cell Rep. 2022 Sep 20;40(12):111373. doi: 10.1016/j.celrep.2022.111373.
223 Ueda Y, Mogami H, Kawamura Y, Takakura M, Inohaya A, Yasuda E, Matsuzaka Y, Chigusa Y, Ito S, Mandai M, Kondoh E.
Cervical MUC5B and MUC5AC are Barriers to Ascending Pathogens During Pregnancy.
J Clin Endocrinol Metab. 2022 Nov 23;107(11):3010-3021. doi: 10.1210/clinem/dgac545.
224 Suno R, Sugita Y, Morimoto K, Takazaki H, Tsujimoto H, Hirose M, Suno-Ikeda C, Nomura N, Hino T, Inoue A, Iwasaki K, Kato T, Iwata S, Kobayashi T.
Structural insights into the G protein selectivity revealed by the human EP3-G(i) signaling complex.
Cell Rep. 2022 Sep 13;40(11):111323. doi: 10.1016/j.celrep.2022.111323.
225 Kawamura Y, Mogami H, Yasuda E, Takakura M, Matsuzaka Y, Ueda Y, Inohaya A, Kawasaki K, Chigusa Y, Mandai M, Kondoh E.
Fetal macrophages assist in the repair of ruptured amnion through the induction of epithelial-mesenchymal transition.
Sci Signal. 2022 Sep 13;15(751):eabi5453. doi: 10.1126/scisignal.abi5453. Epub 2022 Sep 13.
226 Yaku A, Inagaki T, Asano R, Okazawa M, Mori H, Sato A, Hia F, Masaki T, Manabe Y, Ishibashi T, Vandenbon A, Nakatsuka Y, Akaki K, Yoshinaga M, Uehata T, Mino T, Morita S, Ishibashi-Ueda H, Morinobu A, Tsujimura T, Ogo T, Nakaoka Y, Takeuchi O.
Regnase-1 Prevents Pulmonary Arterial Hypertension Through mRNA Degradation of Interleukin-6 and Platelet-Derived Growth Factor in Alveolar Macrophages.
Circulation. 2022 Sep 27;146(13):1006-1022. doi: 10.1161/CIRCULATIONAHA.122.059435. Epub 2022 Aug 23.
227 Itoga M, Yamanishi M, Udagawa T, Kobayashi A, Maekawa K, Takemoto Y, Naka H.
Iridium-catalyzed α-selective deuteration of alcohols.
Chem Sci. 2022 Jul 6;13(30):8744-8751. doi: 10.1039/d2sc01805e. eCollection 2022 Aug 4.
228 Koyauchi T, Niida H, Motegi A, Sakai S, Uchida C, Ohhata T, Iijima K, Yokoyama A, Suda T, Kitagawa M.
Chromatin-remodeling factor BAZ1A/ACF1 targets UV damage sites in an MLL1-dependent manner to facilitate nucleotide excision repair.
Biochim Biophys Acta Mol Cell Res. 2022 Nov;1869(11):119332. doi: 10.1016/j.bbamcr.2022.119332. Epub 2022 Aug 5.
229 Zhang Z, Nomura N, Muramoto Y, Ekimoto T, Uemura T, Liu K, Yui M, Kono N, Aoki J, Ikeguchi M, Noda T, Iwata S, Ohto U, Shimizu T.
Structure of SARS-CoV-2 membrane protein essential for virus assembly.
Nat Commun. 2022 Aug 5;13(1):4399. doi: 10.1038/s41467-022-32019-3.
230 Takeda Y, Dai P.
Chronic Fatty Acid Depletion Induces Uncoupling Protein 1 (UCP1) Expression to Coordinate Mitochondrial Inducible Proton Leak in a Human-Brown-Adipocyte Model.
Cells. 2022 Jun 27;11(13):2038. doi: 10.3390/cells11132038.
231 Maeda R, Fujita J, Konishi Y, Kazuma Y, Yamazaki H, Anzai I, Watanabe T, Yamaguchi K, Kasai K, Nagata K, Yamaoka Y, Miyakawa K, Ryo A, Shirakawa K, Sato K, Makino F, Matsuura Y, Inoue T, Imura A, Namba K, Takaori-Kondo A.
A panel of nanobodies recognizing conserved hidden clefts of all SARS-CoV-2 spike variants including Omicron.
Commun Biol. 2022 Jul 6;5(1):669. doi: 10.1038/s42003-022-03630-3.
232 Kato N, Nanjo T, Takemoto Y. A Pyridine-Based Donor–Acceptor Molecule: A Highly Reactive Organophotocatalyst That Enables the Reductive Cleavage of C–Br Bonds through Halogen Bonding. ACS Catal. 2022 Jul 1;12(13):7843–9. doi:10.1021/acscatal.2c02067
233 Kimura T, Hamada S, Furuta T, Takemoto Y, Kobayashi Y.
N-Acylimino-λ(3)-iodanes from the Metathesis of Iodosoarenes and Nitriles for the Photoinduced C-H Perfluoroacylamination of (Hetero)Arenes.
Org Lett. 2022 Jul 8;24(26):4835-4839. doi: 10.1021/acs.orglett.2c02054. Epub 2022 Jun 27.
234 Naruse C, Sugihara K, Miyazaki T, Pan X, Sugiyama F, Asano M.
A degron system targeting endogenous PD-1 inhibits the growth of tumor cells in mice.
NAR Cancer. 2022 Jun 17;4(2):zcac019. doi: 10.1093/narcan/zcac019. eCollection 2022 Jun.
235 Ohgushi M, Taniyama N, Vandenbon A, Eiraku M.
Delamination of trophoblast-like syncytia from the amniotic ectodermal analogue in human primed embryonic stem cell-based differentiation model.
Cell Rep. 2022 Jun 21;39(12):110973. doi: 10.1016/j.celrep.2022.110973.
236 Ishida Y, Tasaki K, Katoh Y, Nakayama K.
Molecular basis underlying the ciliary defects caused by IFT52 variations found in skeletal ciliopathies.
Mol Biol Cell. 2022 Aug 1;33(9):ar83. doi: 10.1091/mbc.E22-05-0188. Epub 2022 Jun 15.
237 Kurose T, Itoga M, Nanjo T, Takemoto Y, Tsukano C. Total Synthesis of Lyconesidine B: Approach to a Three-Dimensional Tetracyclic Skeleton of Amine-Type Fawcettimine Core and Studies of Asymmetric Synthesis. bull Chem Soc Jpn. 2022 Jun 15;95(6):871–81. doi:10.1246/bcsj.20220049
238 Yamauchi I, Sakane Y, Okuno Y, Sugawa T, Hakata T, Fujita H, Okamoto K, Taura D, Yamashita T, Hirota K, Ueda Y, Fujii T, Yasoda A, Inagaki N.
High-throughput Screening in Combination With a Cohort Study for Iodothyronine Deiodinases.
Endocrinology. 2022 Aug 1;163(8):bqac090. doi: 10.1210/endocr/bqac090.
239 Satoda Y, Noguchi T, Fujii T, Taniguchi A, Katoh Y, Nakayama K.
BROMI/TBC1D32 together with CCRK/CDK20 and FAM149B1/JBTS36 contributes to intraflagellar transport turnaround involving ICK/CILK1.
Mol Biol Cell. 2022 Aug 1;33(9):ar79. doi: 10.1091/mbc.E22-03-0089. Epub 2022 May 24.
240 Asami J, Kimura KT, Fujita-Fujiharu Y, Ishida H, Zhang Z, Nomura Y, Liu K, Uemura T, Sato Y, Ono M, Yamamoto M, Noda T, Shigematsu H, Drew D, Iwata S, Shimizu T, Nomura N, Ohto U.
Structure of the bile acid transporter and HBV receptor NTCP.
Nature. 2022 Jun;606(7916):1021-1026. doi: 10.1038/s41586-022-04845-4. Epub 2022 May 17.
241 Park JH, Iwamoto M, Yun JH, Uchikubo-Kamo T, Son D, Jin Z, Yoshida H, Ohki M, Ishimoto N, Mizutani K, Oshima M, Muramatsu M, Wakita T, Shirouzu M, Liu K, Uemura T, Nomura N, Iwata S, Watashi K, Tame JRH, Nishizawa T, Lee W, Park SY.
Structural insights into the HBV receptor and bile acid transporter NTCP.
Nature. 2022 Jun;606(7916):1027-1031. doi: 10.1038/s41586-022-04857-0. Epub 2022 May 17.
242 Tse KM, Vandenbon A, Cui X, Mino T, Uehata T, Yasuda K, Sato A, Tsujimura T, Hia F, Yoshinaga M, Kinoshita M, Okuno T, Takeuchi O.
Enhancement of Regnase-1 expression with stem loop-targeting antisense oligonucleotides alleviates inflammatory diseases.
Sci Transl Med. 2022 May 11;14(644):eabo2137. doi: 10.1126/scitranslmed.abo2137. Epub 2022 May 11.
243 Nanjo T, Oshita T, Matsumoto A, Takemoto Y.
Late-Stage Installation of Dehydroamino Acid Motifs into Peptides Enabled by an N-Chloropeptide Strategy.
Chemistry. 2022 Jun 27;28(36):e202201120. doi: 10.1002/chem.202201120. Epub 2022 May 26.
244 Tokuhiro Y, Yoshikawa K, Murayama S, Nanjo T, Takemoto Y. Highly Stereoselective, Organocatalytic Mannich-type Addition of Glyoxylate Cyanohydrin: A Versatile Building Block for the Asymmetric Synthesis of β-Amino-α-ketoacids. ACS Catal. 2022 May 6;12(9):5292–304. doi:10.1021/acscatal.2c00950
245 Mori Y, Miyake M, Hosoda Y, Miki A, Takahashi A, Muraoka Y, Miyata M, Sato T, Tamura H, Ooto S, Yamada R, Yamashiro K, Nakamura M, Tajima A, Nagasaki M, Honda S, Tsujikawa A.
Genome-wide Survival Analysis for Macular Neovascularization Development in Central Serous Chorioretinopathy Revealed Shared Genetic Susceptibility with Polypoidal Choroidal Vasculopathy.
Ophthalmology. 2022 Sep;129(9):1034-1042. doi: 10.1016/j.ophtha.2022.04.018. Epub 2022 Apr 29.
246 Yamaoka Y, Yamakawa T, Tateishi K, Takasu K. Total Synthesis of Cryptopleurine and Its Analogues. Synthesis. 2022 May;54(10):2415–22. doi:10.1055/a-1730-8628
247 Liang H, Li Z, Liu Y, Murayama S, Naka H, Maruoka K. Synthesis of optically pure, deuterated Maruoka Catalysts and their chemical reactivity. Tetrahedron Letters. 2022 Apr 27;96:153753. doi:10.1016/j.tetlet.2022.153753
248 Takeda Y, Dai P.
Capsaicin directly promotes adipocyte browning in the chemical compound-induced brown adipocytes converted from human dermal fibroblasts.
Sci Rep. 2022 Apr 22;12(1):6612. doi: 10.1038/s41598-022-10644-8.
249 Someya Y, Iima M, Imai H, Yoshizawa A, Kataoka M, Isoda H, Le Bihan D, Nakamoto Y.
Investigation of breast cancer microstructure and microvasculature from time-dependent DWI and CEST in correlation with histological biomarkers.
Sci Rep. 2022 Apr 20;12(1):6523. doi: 10.1038/s41598-022-10081-7.
250 Chong YK, Tartey S, Yoshikawa Y, Imami K, Li S, Yoshinaga M, Hirabayashi A, Liu G, Vandenbon A, Hia F, Uehata T, Mino T, Suzuki Y, Noda T, Ferrandon D, Standley DM, Ishihama Y, Takeuchi O.
Cyclin J-CDK complexes limit innate immune responses by reducing proinflammatory changes in macrophage metabolism.
Sci Signal. 2022 Apr 12;15(729):eabm5011. doi: 10.1126/scisignal.abm5011. Epub 2022 Apr 12.
251 Kumagai K, Shimizu T, Takai A, Kakiuchi N, Takeuchi Y, Hirano T, Takeda H, Mizuguchi A, Teramura M, Ito T, Iguchi E, Nikaido M, Eso Y, Takahashi K, Ueda Y, Miyamoto S, Obama K, Ogawa S, Marusawa H, Seno H.
Expansion of Gastric Intestinal Metaplasia with Copy Number Aberrations Contributes to Field Cancerization.
Cancer Res. 2022 May 3;82(9):1712-1723. doi: 10.1158/0008-5472.CAN-21-1523.
252 Kuno S, Fujita H, Tanaka YK, Ogra Y, Iwai K.
Iron-induced NCOA4 condensation regulates ferritin fate and iron homeostasis.
EMBO Rep. 2022 May 4;23(5):e54278. doi: 10.15252/embr.202154278. Epub 2022 Mar 23.
253 Liu W, Ota M, Tabushi M, Takahashi Y, Takakura Y.
Development of allergic rhinitis immunotherapy using antigen-loaded small extracellular vesicles.
J Control Release. 2022 May;345:433-442. doi: 10.1016/j.jconrel.2022.03.016. Epub 2022 Mar 14.
254 Fujita-Fujiharu Y, Sugita Y, Takamatsu Y, Houri K, Igarashi M, Muramoto Y, Nakano M, Tsunoda Y, Taniguchi I, Becker S, Noda T.
Structural insight into Marburg virus nucleoprotein-RNA complex formation.
Nat Commun. 2022 Mar 4;13(1):1191. doi: 10.1038/s41467-022-28802-x.
255 藤田陽子, 野田岳. フィロウイルスの粒子構造を視る. 医学のあゆみ. 2022 Feb 26;280(9). doi:10.32118/ayu28009933
256 Higashi Y, Ikeda S, Matsumoto K, Satoh S, Komatsu A, Sugiyama H, Tamanoi F.
Tumor Accumulation of PIP-Based KRAS Inhibitor KR12 Evaluated by the Use of a Simple, Versatile Chicken Egg Tumor Model.
Cancers (Basel). 2022 Feb 14;14(4):951. doi: 10.3390/cancers14040951.
257 Hirota K, Ooka M, Shimizu N, Yamada K, Tsuda M, Ibrahim MA, Yamada S, Sasanuma H, Masutani M, Takeda S.
XRCC1 counteracts poly(ADP ribose)polymerase (PARP) poisons, olaparib and talazoparib, and a clinical alkylating agent, temozolomide, by promoting the removal of trapped PARP1 from broken DNA.
Genes Cells. 2022 May;27(5):331-344. doi: 10.1111/gtc.12929. Epub 2022 Mar 1.
258 Kaba S, Kawai Y, Tanigami Y, Ohnishi H, Kita T, Yoshimatsu M, Omori K, Kishimoto Y.
Peroxisome Proliferator-Activated Receptor-γ Agonist Attenuates Vocal Fold Fibrosis in Rats via Regulation of Macrophage Activation.
Am J Pathol. 2022 May;192(5):771-782. doi: 10.1016/j.ajpath.2022.02.002. Epub 2022 Feb 19.
259 Matsuoka R, Fudim R, Jung S, Zhang C, Bazzone A, Chatzikyriakidou Y, Robinson CV, Nomura N, Iwata S, Landreh M, Orellana L, Beckstein O, Drew D.
Structure, mechanism and lipid-mediated remodeling of the mammalian Na(+)/H(+) exchanger NHA2.
Nat Struct Mol Biol. 2022 Feb;29(2):108-120. doi: 10.1038/s41594-022-00738-2. Epub 2022 Feb 16.
260 Ichise H, Tsukamoto S, Hirashima T, Konishi Y, Oki C, Tsukiji S, Iwano S, Miyawaki A, Sumiyama K, Terai K, Matsuda M.
Functional visualization of NK cell-mediated killing of metastatic single tumor cells.
Elife. 2022 Feb 3;11:e76269. doi: 10.7554/eLife.76269.
261 Inuki S, Tabuchi H, Matsuzaki C, Yonejima Y, Hisa K, Kimura I, Yamamoto K, Ohno H.
Chemical Synthesis and Evaluation of Exopolysaccharide Fragments Produced by Leuconostoc mesenteroides Strain NTM048.
Chem Pharm Bull (Tokyo). 2022;70(2):155-161. doi: 10.1248/cpb.c21-00919.
262 Kishi KE, Kim YS, Fukuda M, Inoue M, Kusakizako T, Wang PY, Ramakrishnan C, Byrne EFX, Thadhani E, Paggi JM, Matsui TE, Yamashita K, Nagata T, Konno M, Quirin S, Lo M, Benster T, Uemura T, Liu K, Shibata M, Nomura N, Iwata S, Nureki O, Dror RO, Inoue K, Deisseroth K, Kato HE.
Structural basis for channel conduction in the pump-like channelrhodopsin ChRmine.
Cell. 2022 Feb 17;185(4):672-689.e23. doi: 10.1016/j.cell.2022.01.007. Epub 2022 Feb 2.
263 Tada T, Ohnishi H, Yamamoto N, Kuwata F, Hayashi Y, Okuyama H, Morino T, Kasai Y, Kojima H, Omori K.
Transplantation of a human induced pluripotent stem cell-derived airway epithelial cell sheet into the middle ear of rats.
Regen Ther. 2022 Jan 14;19:77-87. doi: 10.1016/j.reth.2022.01.001. eCollection 2022 Mar.
264 Mukai Y, Horie M, Kojima S, Kawasaki J, Maeda K, Tomonaga K.
An endogenous bornavirus-like nucleoprotein in miniopterid bats retains the RNA-binding properties of the original viral protein.
FEBS Lett. 2022 Feb;596(3):323-337. doi: 10.1002/1873-3468.14290. Epub 2022 Jan 30.
265 Hirota K, Hirashima T, Horikawa K, Yasoda A, Matsuda M.
C-type Natriuretic Peptide-induced PKA Activation Promotes Endochondral Bone Formation in Hypertrophic Chondrocytes.
Endocrinology. 2022 Mar 1;163(3):bqac005. doi: 10.1210/endocr/bqac005.
266 Takada N, Takasugi M, Nonaka Y, Kamiya T, Takemura K, Satoh J, Ito S, Fujimoto K, Uematsu S, Yoshida K, Morita T, Nakamura H, Uezumi A, Ohtani N.
Galectin-3 promotes the adipogenic differentiation of PDGFRα+ cells and ectopic fat formation in regenerating muscle.
Development. 2022 Feb 1;149(3):dev199443. doi: 10.1242/dev.199443. Epub 2022 Feb 3.
267 Kameda Y, Chuaychob S, Tanaka M, Liu Y, Okada R, Fujimoto K, Nakamura T, Yokokawa R.
Three-dimensional tissue model in direct contact with an on-chip vascular bed enabled by removable membranes.
Lab Chip. 2022 Feb 1;22(3):641-651. doi: 10.1039/d1lc00751c.
268 Qiu H, Tsurumi Y, Katoh Y, Nakayama K.
Combinations of deletion and missense variations of the dynein-2 DYNC2LI1 subunit found in skeletal ciliopathies cause ciliary defects.
Sci Rep. 2022 Jan 7;12(1):31. doi: 10.1038/s41598-021-03950-0.
269 Nanjo T, Matsugasako T, Maruo Y, Takemoto Y.
Photocatalytic C-O Bond Cleavage of Alcohols Using Xanthate Salts.
Org Lett. 2022 Jan 14;24(1):359-363. doi: 10.1021/acs.orglett.1c04029. Epub 2021 Dec 27.
270 Zhou Z, Qiu H, Castro-Araya RF, Takei R, Nakayama K, Katoh Y.
Impaired cooperation between IFT74/BBS22-IFT81 and IFT25-IFT27/BBS19 causes Bardet-Biedl syndrome.
Hum Mol Genet. 2022 May 19;31(10):1681-1693. doi: 10.1093/hmg/ddab354.
271 Kawamoto Y, Liu W, Yum JH, Park S, Sugiyama H, Takahashi Y, Takakura Y.
Enhanced Immunostimulatory Activity of Covalent DNA Dendrons.
Chembiochem. 2022 Feb 16;23(4):e202100583. doi: 10.1002/cbic.202100583. Epub 2021 Dec 23.
272 Ito K, Kariya M, Yasui K, Takahashi Y, Takakura Y.
Development of Hydrophobic Interaction-based DNA Supramolecules as Efficient Delivery Carriers of CpG DNA to Immune cells.
J Pharm Sci. 2022 Apr;111(4):1133-1141. doi: 10.1016/j.xphs.2021.11.027. Epub 2021 Dec 4.
273 Kuwata F, Ohnishi H, Yamamoto N, Takezawa T, Yamashita M, Okuyama H, Hayashi Y, Yoshimatsu M, Kitada Y, Tada T, Kobayashi M, Omori K.
Transplantation of Human Induced Pluripotent Stem Cell-Derived Airway Cells on Vitrigel Membrane into Rat Nasal Cavity.
Tissue Eng Part A. 2022 Mar 30. doi: 10.1089/ten.TEA.2021.0071. Online ahead of print.
274 Lin HH, Horie M, Tomonaga K.
A comprehensive profiling of innate immune responses in Eptesicus bat cells.
Microbiol Immunol. 2022 Mar;66(3):97-112. doi: 10.1111/1348-0421.12952. Epub 2022 Jan 31.
275 Sato Y, Oguchi A, Fukushima Y, Masuda K, Toriu N, Taniguchi K, Yoshikawa T, Cui X, Kondo M, Hosoi T, Komidori S, Shimizu Y, Fujita H, Jiang L, Kong Y, Yamanashi T, Seita J, Yamamoto T, Toyokuni S, Hamazaki Y, Hattori M, Yoshikai Y, Boor P, Floege J, Kawamoto H, Murakawa Y, Minato N, Yanagita M.
CD153/CD30 signaling promotes age-dependent tertiary lymphoid tissue expansion and kidney injury.
J Clin Invest. 2022 Jan 18;132(2):e146071. doi: 10.1172/JCI146071.
276 Shirakashi M, Maruya M, Hirota K, Tsuruyama T, Matsuo T, Watanabe R, Murata K, Tanaka M, Ito H, Yoshifuji H, Ohmura K, Elewaut D, Sakaguchi S, Fagarasan S, Mimori T, Hashimoto M.
Effect of Impaired T Cell Receptor Signaling on the Gut Microbiota in a Mouse Model of Systemic Autoimmunity.
Arthritis Rheumatol. 2022 Apr;74(4):641-653. doi: 10.1002/art.42016. Epub 2022 Feb 25.
277 Hashimoto H, Ueda Y, Takasu K, Kawabata T. Catalytic Substrate-Selective Silylation of Primary Alcohols via Remote Functional-Group Discrimination. Angewandte Chemie International Edition. 2022;61(18):e202114118. doi:10.1002/anie.202114118
278 Yumura T, Nanjo T, Takemoto Y. Boronic Acid-Mediated Photocatalysis Enables the Intramolecular Hydroacylation of Olefins Using Carboxylic Acids. European Journal of Organic Chemistry. 2022;2022(26):e202200082. doi:10.1002/ejoc.202200082
279 Suezawa T, Kanagaki S, Moriguchi K, Masui A, Nakao K, Toyomoto M, Tamai K, Mikawa R, Hirai T, Murakami K, Hagiwara M, Gotoh S.
Disease modeling of pulmonary fibrosis using human pluripotent stem cell-derived alveolar organoids.
Stem Cell Reports. 2021 Dec 14;16(12):2973-2987. doi: 10.1016/j.stemcr.2021.10.015. Epub 2021 Nov 18.
280 Suezawa T, Kanagaki S, Korogi Y, Nakao K, Hirai T, Murakami K, Hagiwara M, Gotoh S.
Modeling of lung phenotype of Hermansky-Pudlak syndrome type I using patient-specific iPSCs.
Respir Res. 2021 Nov 4;22(1):284. doi: 10.1186/s12931-021-01877-8.
281 Tawatari T, Takasu K, Takikawa H.
2-(Chlorodiisopropylsilyl)-6-(trimethylsilyl)phenyl triflate: a modified platform for intramolecular benzyne cycloadditions.
Chem Commun (Camb). 2021 Nov 9;57(89):11863-11866. doi: 10.1039/d1cc05264k.
282 Komatsu A, Matsumoto K, Yoshimatsu Y, Sin Y, Kubota A, Saito T, Mizumoto A, Ohashi S, Muto M, Noguchi R, Kondo T, Tamanoi F.
The CAM Model for CIC-DUX4 Sarcoma and Its Potential Use for Precision Medicine.
Cells. 2021 Oct 1;10(10):2613. doi: 10.3390/cells10102613.
283 Noguchi T, Nakamura K, Satoda Y, Katoh Y, Nakayama K.
CCRK/CDK20 regulates ciliary retrograde protein trafficking via interacting with BROMI/TBC1D32.
PLoS One. 2021 Oct 8;16(10):e0258497. doi: 10.1371/journal.pone.0258497. eCollection 2021.
284 Komatsu H, Ikeuchi T, Tsuno H, Arichi N, Yasui K, Oishi S, Inuki S, Fukazawa A, Ohno H.
Construction of Tricyclic Nitrogen Heterocycles by a Gold(I)-Catalyzed Cascade Cyclization of Allenynes and Application to Polycyclic π-Electron Systems.
Angew Chem Int Ed Engl. 2021 Dec 20;60(52):27019-27025. doi: 10.1002/anie.202111267. Epub 2021 Nov 22.
285 Takenaga T, Zhang Z, Muramoto Y, Fehling SK, Hirabayashi A, Takamatsu Y, Kajikawa J, Miyamoto S, Nakano M, Urata S, Groseth A, Strecker T, Noda T.
CP100356 Hydrochloride, a P-Glycoprotein Inhibitor, Inhibits Lassa Virus Entry: Implication of a Candidate Pan-Mammarenavirus Entry Inhibitor.
Viruses. 2021 Sep 3;13(9):1763. doi: 10.3390/v13091763.
286 Murakami S, Nanjo T, Takemoto Y.
Photocatalytic Activation of Elemental Sulfur Enables a Chemoselective Three-Component Thioesterification.
Org Lett. 2021 Oct 1;23(19):7650-7655. doi: 10.1021/acs.orglett.1c02904. Epub 2021 Sep 16.
287 Ghilarov D, Inaba-Inoue S, Stepien P, Qu F, Michalczyk E, Pakosz Z, Nomura N, Ogasawara S, Walker GC, Rebuffat S, Iwata S, Heddle JG, Beis K.
Molecular mechanism of SbmA, a promiscuous transporter exploited by antimicrobial peptides.
Sci Adv. 2021 Sep 10;7(37):eabj5363. doi: 10.1126/sciadv.abj5363. Epub 2021 Sep 8.
288 Kinouchi H, Sugimoto K, Yamaoka Y, Takikawa H, Takasu K.
Oxidative β-Cleavage of Fused Cyclobutanols Leading to Hydrofuran-Fused Polycyclic Aromatic Compounds.
J Org Chem. 2021 Sep 17;86(18):12615-12622. doi: 10.1021/acs.joc.1c01108. Epub 2021 Sep 2.
289 Murakami K, Horii S, Hanaki M, Irie K.
Searching for Natural Products That Delay Nucleation Phase and Promote Elongation Phase of Amyloid β42 toward Alzheimer's Disease Therapeutics.
ACS Chem Neurosci. 2021 Sep 15;12(18):3467-3476. doi: 10.1021/acschemneuro.1c00489. Epub 2021 Aug 31.
290 Fujisawa S, Qiu H, Nozaki S, Chiba S, Katoh Y, Nakayama K.
ARL3 and ARL13B GTPases participate in distinct steps of INPP5E targeting to the ciliary membrane.
Biol Open. 2021 Sep 15;10(9):bio058843. doi: 10.1242/bio.058843. Epub 2021 Sep 28.
291 Tsukano C, Yagita R, Heike T, Mohammed TA, Nishibayashi K, Irie K, Takemoto Y.
Asymmetric Total Synthesis of Shagenes A and B.
Angew Chem Int Ed Engl. 2021 Oct 18;60(43):23106-23111. doi: 10.1002/anie.202109786. Epub 2021 Sep 7.
292 武長徹, 張子涵, 野田岳志. ラッサウイルスの細胞侵入阻害薬の開発. 生体の科学. 2021 Aug 15;72(4). doi:10.11477/mf.2425201375
293 Yoshinari Y, Kosakamoto H, Kamiyama T, Hoshino R, Matsuoka R, Kondo S, Tanimoto H, Nakamura A, Obata F, Niwa R.
The sugar-responsive enteroendocrine neuropeptide F regulates lipid metabolism through glucagon-like and insulin-like hormones in Drosophila melanogaster.
Nat Commun. 2021 Aug 10;12(1):4818. doi: 10.1038/s41467-021-25146-w.
294 Neville SL, Sjöhamn J, Watts JA, MacDermott-Opeskin H, Fairweather SJ, Ganio K, Carey Hulyer A, McGrath AP, Hayes AJ, Malcolm TR, Davies MR, Nomura N, Iwata S, O'Mara ML, Maher MJ, McDevitt CA.
The structural basis of bacterial manganese import.
Sci Adv. 2021 Aug 6;7(32):eabg3980. doi: 10.1126/sciadv.abg3980. Print 2021 Aug.
295 Okamoto HH, Miyauchi H, Inoue A, Raimondi F, Tsujimoto H, Kusakizako T, Shihoya W, Yamashita K, Suno R, Nomura N, Kobayashi T, Iwata S, Nishizawa T, Nureki O.
Cryo-EM structure of the human MT(1)-G(i) signaling complex.
Nat Struct Mol Biol. 2021 Aug;28(8):694-701. doi: 10.1038/s41594-021-00634-1. Epub 2021 Aug 5.
296 Iwai S, Ikeda HO, Mera H, Nishitani K, Saito M, Tsujikawa A, Kakizuka A.
KUS121 attenuates the progression of monosodium iodoacetate-induced osteoarthritis in rats.
Sci Rep. 2021 Aug 2;11(1):15651. doi: 10.1038/s41598-021-95173-6.
297 Garcia BCB, Horie M, Kojima S, Makino A, Tomonaga K.
BUD23-TRMT112 interacts with the L protein of Borna disease virus and mediates the chromosomal tethering of viral ribonucleoproteins.
Microbiol Immunol. 2021 Nov;65(11):492-504. doi: 10.1111/1348-0421.12934. Epub 2021 Sep 17.
298 Uehata T, Takeuchi O.
Post-transcriptional regulation of immunological responses by Regnase-1-related RNases.
Int Immunol. 2021 Nov 25;33(12):859-865. doi: 10.1093/intimm/dxab048.
299 Ajiro M, Awaya T, Kim YJ, Iida K, Denawa M, Tanaka N, Kurosawa R, Matsushima S, Shibata S, Sakamoto T, Studer L, Krainer AR, Hagiwara M.
Therapeutic manipulation of IKBKAP mis-splicing with a small molecule to cure familial dysautonomia.
Nat Commun. 2021 Jul 23;12(1):4507. doi: 10.1038/s41467-021-24705-5.
300 Nakano M, Sugita Y, Kodera N, Miyamoto S, Muramoto Y, Wolf M, Noda T.
Ultrastructure of influenza virus ribonucleoprotein complexes during viral RNA synthesis.
Commun Biol. 2021 Jul 9;4(1):858. doi: 10.1038/s42003-021-02388-4.
301 Yamada K ichi, Fujiwara S, Inokuma T, Sugano M, Yamaoka Y, Takasu K. The rationale for stereoinduction in conjugate addition to alkylidenemalonates bearing a menthol-derived chiral auxiliary. Tetrahedron. 2021 Jul 2;91:132220. doi:10.1016/j.tet.2021.132220
302 Miyata Y, Nishida E.
Protein quality control of DYRK family protein kinases by the Hsp90-Cdc37 molecular chaperone.
Biochim Biophys Acta Mol Cell Res. 2021 Sep;1868(10):119081. doi: 10.1016/j.bbamcr.2021.119081. Epub 2021 Jun 18.
303 Greiner LC, Inuki S, Arichi N, Oishi S, Suzuki R, Iwai T, Sawamura M, Hashmi ASK, Ohno H.
Access to Indole-Fused Benzannulated Medium-Sized Rings through a Gold(I)-Catalyzed Cascade Cyclization of Azido-Alkynes.
Chemistry. 2021 Sep 9;27(51):12992-12997. doi: 10.1002/chem.202101824. Epub 2021 Jul 9.
304 Maeda S, Shiimura Y, Asada H, Hirata K, Luo F, Nango E, Tanaka N, Toyomoto M, Inoue A, Aoki J, Iwata S, Hagiwara M.
Endogenous agonist-bound S1PR3 structure reveals determinants of G protein-subtype bias.
Sci Adv. 2021 Jun 9;7(24):eabf5325. doi: 10.1126/sciadv.abf5325. Print 2021 Jun.
305 Fujino K, Horie M, Kojima S, Shimizu S, Nabekura A, Kobayashi H, Makino A, Honda T, Tomonaga K.
A Human Endogenous Bornavirus-Like Nucleoprotein Encodes a Mitochondrial Protein Associated with Cell Viability.
J Virol. 2021 Jun 24;95(14):e0203020. doi: 10.1128/JVI.02030-20. Epub 2021 Jun 24.
306 Inoue M, Enomoto M, Yoshimura M, Mizowaki T.
Pharmacological inhibition of sodium-calcium exchange activates NADPH oxidase and induces infection-independent NETotic cell death.
Redox Biol. 2021 Jul;43:101983. doi: 10.1016/j.redox.2021.101983. Epub 2021 Apr 26.
307 Jin F, Sun M, Fujii T, Yamada Y, Wang J, Maturana AD, Wada M, Su S, Ma J, Takeda H, Kusakizako T, Tomita A, Nakada-Nakura Y, Liu K, Uemura T, Nomura Y, Nomura N, Ito K, Nureki O, Namba K, Iwata S, Yu Y, Hattori M.
The structure of MgtE in the absence of magnesium provides new insights into channel gating.
PLoS Biol. 2021 Apr 27;19(4):e3001231. doi: 10.1371/journal.pbio.3001231. eCollection 2021 Apr.
308 Egawa G, Egawa K, Kabashima K.
Is breakthrough chickenpox caused by different genotypes of Varicella zoster virus?.
Pediatr Int. 2021 Apr;63(4):478-480. doi: 10.1111/ped.14440. Epub 2021 Apr 3.
309 Nakamoto H, Yokoyama Y, Suzuki T, Miyamoto Y, Fujishiro T, Morikawa M, Miyata Y.
A cyclic lipopeptide surfactin is a species-selective Hsp90 inhibitor that suppresses cyanobacterial growth.
J Biochem. 2021 Oct 11;170(2):255-264. doi: 10.1093/jb/mvab037.
310 Tagawa M, Ikeda HO, Inoue Y, Iwai S, Iida Y, Hata M, Asaka I, Tsujikawa A.
Deterioration of phagocytosis in induced pluripotent stem cell-derived retinal pigment epithelial cells established from patients with retinitis pigmentosa carrying Mer tyrosine kinase mutations.
Exp Eye Res. 2021 Apr;205:108503. doi: 10.1016/j.exer.2021.108503. Epub 2021 Feb 17.
311 Yoshimatsu M, Ohnishi H, Zhao C, Hayashi Y, Kuwata F, Kaba S, Okuyama H, Kawai Y, Hiwatashi N, Kishimoto Y, Sakamoto T, Ikeya M, Omori K.
In vivo regeneration of rat laryngeal cartilage with mesenchymal stem cells derived from human induced pluripotent stem cells via neural crest cells.
Stem Cell Res. 2021 Apr;52:102233. doi: 10.1016/j.scr.2021.102233. Epub 2021 Feb 11.
312 Toyomoto M, Inoue A, Iida K, Denawa M, Kii I, Ngako Kadji FM, Kishi T, Im D, Shimamura T, Onogi H, Yoshida S, Iwata S, Aoki J, Hosoya T, Hagiwara M.
S1PR3-G(12)-biased agonist ALESIA targets cancer metabolism and promotes glucose starvation.
Cell Chem Biol. 2021 Aug 19;28(8):1132-1144.e9. doi: 10.1016/j.chembiol.2021.01.004. Epub 2021 Feb 8.
313 Moribe F, Nishikori M, Takashima T, Taniyama D, Onishi N, Arima H, Sasanuma H, Akagawa R, Elloumi F, Takeda S, Pommier Y, Morii E, Takaori-Kondo A, Murai J.
Epigenetic suppression of SLFN11 in germinal center B-cells during B-cell development.
PLoS One. 2021 Jan 29;16(1):e0237554. doi: 10.1371/journal.pone.0237554. eCollection 2021.
314 Mu A, Hira A, Niwa A, Osawa M, Yoshida K, Mori M, Okamoto Y, Inoue K, Kondo K, Kanemaki MT, Matsuda T, Ito E, Kojima S, Nakahata T, Ogawa S, Tanaka K, Matsuo K, Saito MK, Takata M.
Analysis of disease model iPSCs derived from patients with a novel Fanconi anemia-like IBMFS ADH5/ALDH2 deficiency.
Blood. 2021 Apr 15;137(15):2021-2032. doi: 10.1182/blood.2020009111.
315 Kanagaki S, Suezawa T, Moriguchi K, Nakao K, Toyomoto M, Yamamoto Y, Murakami K, Hagiwara M, Gotoh S.
Hydroxypropyl Cyclodextrin Improves Amiodarone-induced Aberrant Lipid Homeostasis of Alveolar Cells.
Am J Respir Cell Mol Biol. 2021 Apr;64(4):504-514. doi: 10.1165/rcmb.2020-0119OC.
316 Yin X, Riva L, Pu Y, Martin-Sancho L, Kanamune J, Yamamoto Y, Sakai K, Gotoh S, Miorin L, De Jesus PD, Yang CC, Herbert KM, Yoh S, Hultquist JF, García-Sastre A, Chanda SK.
MDA5 Governs the Innate Immune Response to SARS-CoV-2 in Lung Epithelial Cells.
Cell Rep. 2021 Jan 12;34(2):108628. doi: 10.1016/j.celrep.2020.108628.
317 Maruno T, Fukuda A, Goto N, Tsuda M, Ikuta K, Hiramatsu Y, Ogawa S, Nakanishi Y, Yamaga Y, Yoshioka T, Takaori K, Uemoto S, Saur D, Chiba T, Seno H.
Visualization of stem cell activity in pancreatic cancer expansion by direct lineage tracing with live imaging.
Elife. 2021 Jan 4;10:e55117. doi: 10.7554/eLife.55117.
318 Qiu H, Fujisawa S, Nozaki S, Katoh Y, Nakayama K.
Interaction of INPP5E with ARL13B is essential for its ciliary membrane retention but dispensable for its ciliary entry.
Biol Open. 2021 Jan 25;10(1):bio057653. doi: 10.1242/bio.057653.
319 Suzuki R, Murata MM, Manguso N, Watanabe T, Mouakkad-Montoya L, Igari F, Rahman MM, Qu Y, Cui X, Giuliano AE, Takeda S, Tanaka H.
The fragility of a structurally diverse duplication block triggers recurrent genomic amplification.
Nucleic Acids Res. 2021 Jan 11;49(1):244-256. doi: 10.1093/nar/gkaa1136.
320 Nojima S, Fujita Y, Kimura KT, Nomura N, Suno R, Morimoto K, Yamamoto M, Noda T, Iwata S, Shigematsu H, Kobayashi T.
Cryo-EM Structure of the Prostaglandin E Receptor EP4 Coupled to G Protein.
Structure. 2021 Mar 4;29(3):252-260.e6. doi: 10.1016/j.str.2020.11.007. Epub 2020 Dec 1.
321 Kanagaki S, Ikeo S, Suezawa T, Yamamoto Y, Seki M, Hirai T, Hagiwara M, Suzuki Y, Gotoh S.
Directed induction of alveolar type I cells derived from pluripotent stem cells via Wnt signaling inhibition.
Stem Cells. 2021 Feb;39(2):156-169. doi: 10.1002/stem.3302. Epub 2020 Nov 26.
322 Kato T, Harada N, Ikeguchi-Ogura E, Sankoda A, Hatoko T, Lu X, Yasuda T, Yamane S, Inagaki N.
Gene expression of nutrient-sensing molecules in I cells of CCK reporter male mice.
J Mol Endocrinol. 2021 Jan;66(1):11-22. doi: 10.1530/JME-20-0134.
323 Hirose Y, Hashiya K, Bando T, Sugiyama H.
Evaluation of the DNA Alkylation Properties of a Chlorambucil-Conjugated Cyclic Pyrrole-Imidazole Polyamide.
Chemistry. 2021 Feb 5;27(8):2782-2788. doi: 10.1002/chem.202004421. Epub 2021 Jan 14.
324 Yamamoto R, Ohnishi H, Omori K, Yamamoto N.
In silico analysis of inner ear development using public whole embryonic body single-cell RNA-sequencing data.
Dev Biol. 2021 Jan 1;469:160-171. doi: 10.1016/j.ydbio.2020.10.009. Epub 2020 Oct 22.
325 Matsuoka T, Motozono C, Hattori A, Kakeya H, Yamasaki S, Oishi S, Ohno H, Inuki S.
The effects of 5-OP-RU stereochemistry on its stability and MAIT-MR1 axis.
Chembiochem. 2021 Feb 15;22(4):672-678. doi: 10.1002/cbic.202000466. Epub 2020 Nov 16.
326 Uchino A, Tsukano C, Imamoto T, Irie K. Synthesis of Alkyl Bridged-Tris-α-Amino Acids as C3-Symmetric and Linear Linkers. European Journal of Organic Chemistry. 2021;2021(9):1370–7. doi:10.1002/ejoc.202001592
327 Yagita R, Irie K, Tsukano C. Studies Toward the Total Synthesis of Schinortriterpenoids: Diastereoselective Synthesis of the Left-Hand Fragment. European Journal of Organic Chemistry. 2021;2021(30):4269–72. doi:10.1002/ejoc.202100510
328 Yamasaki K, Yamauchi A, Inokuma T, Miyakawa Y, Wang Y, Oriez R, et al. Mechanistic Support for Intramolecular Migrative Cyclization of Propargyl Sulfones Provided by Catalytic Asymmetric Induction with a Chiral Counter Cation Strategy. Asian Journal of Organic Chemistry. 2021;10(7):1828–34. doi:10.1002/ajoc.202100274
329 Rahman MM, Mohiuddin M, Shamima Keka I, Yamada K, Tsuda M, Sasanuma H, Andreani J, Guerois R, Borde V, Charbonnier JB, Takeda S.
Genetic evidence for the involvement of mismatch repair proteins, PMS2 and MLH3, in a late step of homologous recombination.
J Biol Chem. 2020 Dec 18;295(51):17460-17475. doi: 10.1074/jbc.RA120.013521.
330 Takeishi A, Kogashi H, Odagiri M, Sasanuma H, Takeda S, Yasui M, Honma M, Suzuki T, Kamiya H, Sugasawa K, Ura K, Sassa A.
Tyrosyl-DNA phosphodiesterases are involved in mutagenic events at a ribonucleotide embedded into DNA in human cells.
PLoS One. 2020 Dec 31;15(12):e0244790. doi: 10.1371/journal.pone.0244790. eCollection 2020.
331 Matsunaga M, Kita T, Yamamoto R, Yamamoto N, Okano T, Omori K, Sakamoto S, Nakagawa T.
Initiation of Supporting Cell Activation for Hair Cell Regeneration in the Avian Auditory Epithelium: An Explant Culture Model.
Front Cell Neurosci. 2020 Nov 12;14:583994. doi: 10.3389/fncel.2020.583994. eCollection 2020.
332 Noura M, Morita K, Kiyose H, Matsuo H, Nishinaka-Arai Y, Kurokawa M, Kamikubo Y, Adachi S.
Pivotal role of DPYSL2A in KLF4-mediated monocytic differentiation of acute myeloid leukemia cells.
Sci Rep. 2020 Nov 20;10(1):20245. doi: 10.1038/s41598-020-76951-0.
333 Shiimura Y, Horita S, Hamamoto A, Asada H, Hirata K, Tanaka M, Mori K, Uemura T, Kobayashi T, Iwata S, Kojima M.
Structure of an antagonist-bound ghrelin receptor reveals possible ghrelin recognition mode.
Nat Commun. 2020 Aug 19;11(1):4160. doi: 10.1038/s41467-020-17554-1.
334 Okazaki M, Kobayashi T, Chiba S, Takei R, Liang L, Nakayama K, Katoh Y.
Formation of the B9-domain protein complex MKS1-B9D2-B9D1 is essential as a diffusion barrier for ciliary membrane proteins.
Mol Biol Cell. 2020 Sep 15;31(20):2259-2268. doi: 10.1091/mbc.E20-03-0208. Epub 2020 Jul 29.
335 Morita D, Iwashita C, Mizutani T, Mori N, Mikami B, Sugita M.
Crystal structure of the ternary complex of TCR, MHC class I and lipopeptides.
Int Immunol. 2020 Nov 23;32(12):805-810. doi: 10.1093/intimm/dxaa050.
336 Maeda R, Ito S, Hashiya K, Bando T, Sugiyama H.
DNA Alkylation of the RUNX-Binding Sequence by CBI-PI Polyamide Conjugates*.
Chemistry. 2020 Nov 17;26(64):14639-14644. doi: 10.1002/chem.202002166. Epub 2020 Oct 6.
337 Nakano T, Shoulkamy MI, Tsuda M, Sasanuma H, Hirota K, Takata M, Masunaga SI, Takeda S, Ide H, Bessho T, Tano K.
Participation of TDP1 in the repair of formaldehyde-induced DNA-protein cross-links in chicken DT40 cells.
PLoS One. 2020 Jun 26;15(6):e0234859. doi: 10.1371/journal.pone.0234859. eCollection 2020.
338 Nyuzuki H, Ito S, Nagasaki K, Nitta Y, Matsui N, Saitoh A, Matsui H.
Degeneration of dopaminergic neurons and impaired intracellular trafficking in Atp13a2 deficient zebrafish.
IBRO Rep. 2020 Jun 1;9:1-8. doi: 10.1016/j.ibror.2020.05.002. eCollection 2020 Dec.
339 Saha LK, Wakasugi M, Akter S, Prasad R, Wilson SH, Shimizu N, Sasanuma H, Huang SN, Agama K, Pommier Y, Matsunaga T, Hirota K, Iwai S, Nakazawa Y, Ogi T, Takeda S.
Topoisomerase I-driven repair of UV-induced damage in NER-deficient cells.
Proc Natl Acad Sci U S A. 2020 Jun 23;117(25):14412-14420. doi: 10.1073/pnas.1920165117. Epub 2020 Jun 8.
340 Nakai S, Oyabu M, Hatazawa Y, Akashi S, Kitamura T, Miura S, Kamei Y.
FOXO1 suppresses PGC-1β gene expression in skeletal muscles.
FEBS Open Bio. 2020 Jul;10(7):1373-1388. doi: 10.1002/2211-5463.12898.
341 Zou Y, Ito S, Yoshino F, Suzuki Y, Zhao L, Komatsu N.
Polyglycerol Grafting Shields Nanoparticles from Protein Corona Formation to Avoid Macrophage Uptake.
ACS Nano. 2020 Jun 23;14(6):7216-7226. doi: 10.1021/acsnano.0c02289. Epub 2020 May 20.
342 Nishimura F, Mogami H, Moriuchi K, Chigusa Y, Mandai M, Kondoh E.
Mechanisms of thrombin-Induced myometrial contractions: Potential targets of progesterone.
PLoS One. 2020 May 4;15(5):e0231944. doi: 10.1371/journal.pone.0231944. eCollection 2020.
343 Akagawa R, Trinh HT, Saha LK, Tsuda M, Hirota K, Yamada S, Shibata A, Kanemaki MT, Nakada S, Takeda S, Sasanuma H.
UBC13-Mediated Ubiquitin Signaling Promotes Removal of Blocking Adducts from DNA Double-Strand Breaks.
iScience. 2020 Apr 24;23(4):101027. doi: 10.1016/j.isci.2020.101027. Epub 2020 Mar 31.
344 Al Mahmud MR, Ishii K, Bernal-Lozano C, Delgado-Sainz I, Toi M, Akamatsu S, Fukumoto M, Watanabe M, Takeda S, Cortés-Ledesma F, Sasanuma H.
TDP2 suppresses genomic instability induced by androgens in the epithelial cells of prostate glands.
Genes Cells. 2020 Jul;25(7):450-465. doi: 10.1111/gtc.12770. Epub 2020 May 5.
345 Shima Y, Morita D, Mizutani T, Mori N, Mikami B, Sugita M.
Crystal structures of lysophospholipid-bound MHC class I molecules.
J Biol Chem. 2020 May 15;295(20):6983-6991. doi: 10.1074/jbc.RA119.011932. Epub 2020 Apr 8.
346 Ibrahim MA, Yasui M, Saha LK, Sasanuma H, Honma M, Takeda S.
Enhancing the sensitivity of the thymidine kinase assay by using DNA repair-deficient human TK6 cells.
Environ Mol Mutagen. 2020 Jul;61(6):602-610. doi: 10.1002/em.22371. Epub 2020 Apr 15.
347 Hasegawa T, Ikeda HO, Gotoh N, Iida K, Iwai S, Nakano N, Kakizuka A, Tsujikawa A.
Effect of VCP modulators on gene expression profiles of retinal ganglion cells in an acute injury mouse model.
Sci Rep. 2020 Mar 6;10(1):4251. doi: 10.1038/s41598-020-61160-6.
348 Murakami K, Obata Y, Sekikawa A, Ueda H, Izuo N, Awano T, Takabe K, Shimizu T, Irie K.
An RNA aptamer with potent affinity for a toxic dimer of amyloid β42 has potential utility for histochemical studies of Alzheimer's disease.
J Biol Chem. 2020 Apr 10;295(15):4870-4880. doi: 10.1074/jbc.RA119.010955. Epub 2020 Mar 2.
349 Itou J, Takahashi R, Sasanuma H, Tsuda M, Morimoto S, Matsumoto Y, Ishii T, Sato F, Takeda S, Toi M.
Estrogen Induces Mammary Ductal Dysplasia via the Upregulation of Myc Expression in a DNA-Repair-Deficient Condition.
iScience. 2020 Feb 21;23(2):100821. doi: 10.1016/j.isci.2020.100821. Epub 2020 Jan 9.
350 de Las Rivas M, Paul Daniel EJ, Narimatsu Y, Compañón I, Kato K, Hermosilla P, Thureau A, Ceballos-Laita L, Coelho H, Bernadó P, Marcelo F, Hansen L, Maeda R, Lostao A, Corzana F, Clausen H, Gerken TA, Hurtado-Guerrero R.
Molecular basis for fibroblast growth factor 23 O-glycosylation by GalNAc-T3.
Nat Chem Biol. 2020 Mar;16(3):351-360. doi: 10.1038/s41589-019-0444-x. Epub 2020 Jan 13.
351 Asada H, Inoue A, Ngako Kadji FM, Hirata K, Shiimura Y, Im D, Shimamura T, Nomura N, Iwanari H, Hamakubo T, Kusano-Arai O, Hisano H, Uemura T, Suno C, Aoki J, Iwata S.
The Crystal Structure of Angiotensin II Type 2 Receptor with Endogenous Peptide Hormone.
Structure. 2020 Apr 7;28(4):418-425.e4. doi: 10.1016/j.str.2019.12.003. Epub 2019 Dec 30.
352 Malinee M, Kumar A, Hidaka T, Horie M, Hasegawa K, Pandian GN, Sugiyama H.
Targeted suppression of metastasis regulatory transcription factor SOX2 in various cancer cell lines using a sequence-specific designer pyrrole-imidazole polyamide.
Bioorg Med Chem. 2020 Feb 1;28(3):115248. doi: 10.1016/j.bmc.2019.115248. Epub 2019 Dec 6.
353 Abe H, Satoh J, Shirasaka Y, Kogure A, Kato H, Ito S, Fujita T.
Priming Phosphorylation of TANK-Binding Kinase 1 by IκB Kinase β Is Essential in Toll-Like Receptor 3/4 Signaling.
Mol Cell Biol. 2020 Feb 12;40(5):e00509-19. doi: 10.1128/MCB.00509-19. Print 2020 Feb 12.
354 Egawa G, Egawa K, Kabashima K.
Case of chickenpox in which varicella zoster virus genotype E was identified for the first time in Japan.
J Dermatol. 2020 Jan;47(1):54-57. doi: 10.1111/1346-8138.15153. Epub 2019 Nov 19.
355 Hirata CL, Ito S, Masutani H.
Dataset on the formation of Thioredoxin interacting protein (Txnip) containing redox sensitive high molecular weight nucleoprotein complexes.
Data Brief. 2019 Nov 29;28:104893. doi: 10.1016/j.dib.2019.104893. eCollection 2020 Feb.
356 Nomura N, Nomura Y, Sato Y, Iwata S.
Crystallographic approaches to study the interaction modes of PD-1- and CTLA-4-blocking antibodies.
Methods Enzymol. 2019;629:383-399. doi: 10.1016/bs.mie.2019.10.008. Epub 2019 Oct 29.
357 Morimoto S, Tsuda M, Bunch H, Sasanuma H, Austin C, Takeda S.
Type II DNA Topoisomerases Cause Spontaneous Double-Strand Breaks in Genomic DNA.
Genes (Basel). 2019 Oct 30;10(11):868. doi: 10.3390/genes10110868.
358 Hirata CL, Ito S, Masutani H.
Thioredoxin interacting protein (Txnip) forms redox sensitive high molecular weight nucleoprotein complexes.
Arch Biochem Biophys. 2019 Nov 30;677:108159. doi: 10.1016/j.abb.2019.108159. Epub 2019 Oct 24.
359 Sassa A, Tada H, Takeishi A, Harada K, Suzuki M, Tsuda M, Sasanuma H, Takeda S, Sugasawa K, Yasui M, Honma M, Ura K.
Processing of a single ribonucleotide embedded into DNA by human nucleotide excision repair and DNA polymerase η.
Sci Rep. 2019 Sep 26;9(1):13910. doi: 10.1038/s41598-019-50421-8.
360 Mukai Y, Tomita Y, Kryukov K, Nakagawa S, Ozawa M, Matsui T, Tomonaga K, Imanishi T, Kawaoka Y, Watanabe T, Horie M.
Identification of a distinct lineage of aviadenovirus from crane feces.
Virus Genes. 2019 Dec;55(6):815-824. doi: 10.1007/s11262-019-01703-w. Epub 2019 Sep 23.
361 Kinjo T, Terai K, Horita S, Nomura N, Sumiyama K, Togashi K, Iwata S, Matsuda M.
FRET-assisted photoactivation of flavoproteins for in vivo two-photon optogenetics.
Nat Methods. 2019 Oct;16(10):1029-1036. doi: 10.1038/s41592-019-0541-5. Epub 2019 Sep 9.
362 Watanabe K, Kanaoka Y, Mizutani S, Uchiyama H, Yajima S, Watada M, Uemura T, Hattori Y.
Interspecies Comparative Analyses Reveal Distinct Carbohydrate-Responsive Systems among Drosophila Species.
Cell Rep. 2019 Sep 3;28(10):2594-2607.e7. doi: 10.1016/j.celrep.2019.08.030.
363 Nozaki S, Castro Araya RF, Katoh Y, Nakayama K.
Requirement of IFT-B-BBSome complex interaction in export of GPR161 from cilia.
Biol Open. 2019 Sep 17;8(9):bio043786. doi: 10.1242/bio.043786.
364 Gothe HJ, Bouwman BAM, Gusmao EG, Piccinno R, Petrosino G, Sayols S, Drechsel O, Minneker V, Josipovic N, Mizi A, Nielsen CF, Wagner EM, Takeda S, Sasanuma H, Hudson DF, Kindler T, Baranello L, Papantonis A, Crosetto N, Roukos V.
Spatial Chromosome Folding and Active Transcription Drive DNA Fragility and Formation of Oncogenic MLL Translocations.
Mol Cell. 2019 Jul 25;75(2):267-283.e12. doi: 10.1016/j.molcel.2019.05.015. Epub 2019 Jun 12.
365 Yamamoto K, Kitawaki T, Sugimoto N, Fujita H, Kawase Y, Takaori-Kondo A, Kadowaki N.
Anti-inflammatory modulation of human myeloid-derived dendritic cell subsets by lenalidomide.
Immunol Lett. 2019 Jul;211:41-48. doi: 10.1016/j.imlet.2019.05.012. Epub 2019 May 26.
366 Kanaoka Y, Skibbe H, Hayashi Y, Uemura T, Hattori Y.
DeTerm: Software for automatic detection of neuronal dendritic branch terminals via an artificial neural network.
Genes Cells. 2019 Jul;24(7):464-472. doi: 10.1111/gtc.12700. Epub 2019 May 28.
367 Okuyama H, Ohnishi H, Nakamura R, Yamashita M, Kishimoto Y, Tateya I, Suehiro A, Gotoh S, Takezawa T, Nakamura T, Omori K.
Transplantation of multiciliated airway cells derived from human iPS cells using an artificial tracheal patch into rat trachea.
J Tissue Eng Regen Med. 2019 Jun;13(6):1019-1030. doi: 10.1002/term.2849. Epub 2019 Apr 24.
368 Mizumoto A, Ohashi S, Kamada M, Saito T, Nakai Y, Baba K, Hirohashi K, Mitani Y, Kikuchi O, Matsubara J, Yamada A, Takahashi T, Lee H, Okuno Y, Kanai M, Muto M.
Combination treatment with highly bioavailable curcumin and NQO1 inhibitor exhibits potent antitumor effects on esophageal squamous cell carcinoma.
J Gastroenterol. 2019 Aug;54(8):687-698. doi: 10.1007/s00535-019-01549-x. Epub 2019 Feb 8.

