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Publication of iSAL Users
2023
| Greiner LC, Arichi N, Inuki S, Ohno H. Gold(I)-Catalyzed Benzylic C(sp(3) )-H Functionalizations: Divergent Synthesis of Indole[a]- and [b]-Fused Polycycles Angew Chem Int Ed Engl. 2023 Jan 16;62(3):e202213653. doi: 10.1002/anie.202213653. Epub 2022 Dec 8. |
| Yamaguchi K, Anzai I, Maeda R, Moriguchi M, Watanabe T, Imura A, Takaori-Kondo A, Inoue T. Structural insights into the rational design of a nanobody that binds with high affinity to the SARS-CoV-2 spike variant J Biochem. 2023 Feb 3;173(2):115-127. doi: 10.1093/jb/mvac096. |
| Akter S, Shimba A, Ikuta K, Mahmud MRA, Yamada S, Sasanuma H, Tsuda M, Sone M, Ago Y, Murai K, Tanaka H, Takeda S. Physiological concentrations of glucocorticoids induce pathological DNA double-strand breaks Genes Cells. 2023 Jan;28(1):53-67. doi: 10.1111/gtc.12993. Epub 2022 Dec 7. |
| Ishikawa H, Menju T, Toyazaki T, Miyamoto H, Chiba N, Noguchi M, Tamari S, Miyata R, Yutaka Y, Tanaka S, Yamada Y, Nakajima D, Ohsumi A, Hamaji M, Okuno Y, Date H. A novel cell-based assay for the high-throughput screening of epithelial-mesenchymal transition inhibitors: Identification of approved and investigational drugs that inhibit epithelial-mesenchymal transition Lung Cancer. 2023 Jan;175:36-46. doi: 10.1016/j.lungcan.2022.11.015. Epub 2022 Nov 23. |
| Wu P, Asada H, Hakamada M, Mabuchi M. Bioengineering of High Cell Density Tissues with Hierarchical Vascular Networks for Ex Vivo Whole Organs Adv Mater. 2023 Mar;35(9):e2209149. doi: 10.1002/adma.202209149. Epub 2023 Jan 1. |
| Najnin RA, Al Mahmud MR, Rahman MM, Takeda S, Sasanuma H, Tanaka H, Murakawa Y, Shimizu N, Akter S, Takagi M, Sunada T, Akamatsu S, He G, Itou J, Toi M, Miyaji M, Tsutsui KM, Keeney S, Yamada S. ATM suppresses c-Myc overexpression in the mammary epithelium in response to estrogen Cell Rep. 2023 Jan 31;42(1):111909. doi: 10.1016/j.celrep.2022.111909. Epub 2022 Dec 30. |
| Kanaoka Y, Onodera K, Watanabe K, Hayashi Y, Usui T, Uemura T, Hattori Y. Inter-organ Wingless/Ror/Akt signaling regulates nutrient-dependent hyperarborization of somatosensory neurons Elife. 2023 Jan 17;12:e79461. doi: 10.7554/eLife.79461. |
| Tsuji A, Masuya T, Arichi N, Inuki S, Murai M, Miyoshi H, Ohno H. Discovery of Bis-sulfonamides as Novel Inhibitors of Mitochondrial NADH-Quinone Oxidoreductase (Complex I) ACS Med Chem Lett. 2023 Jan 24;14(2):211-216. doi: 10.1021/acsmedchemlett.2c00504. eCollection 2023 Feb 9. |
| Nagai T, Terada N, Fujii M, Nagata Y, Nakahara K, Mukai S, Okasho K, Kamiyama Y, Akamatsu S, Kobayashi T, Iida K, Denawa M, Hagiwara M, Inoue T, Ogawa O, Kamoto T. Identification of the α2 chain of interleukin-13 receptor as a potential biomarker for predicting castration resistance of prostate cancer using patient-derived xenograft models Cancer Rep (Hoboken). 2023 Feb;6(2):e1701. doi: 10.1002/cnr2.1701. Epub 2022 Aug 9. |
| Tsuchiya M, Tachibana N, Nagao K, Tamura T, Hamachi I. Organelle-selective click labeling coupled with flow cytometry allows pooled CRISPR screening of genes involved in phosphatidylcholine metabolism Cell Metab. 2023 Jun 6;35(6):1072-1083.e9. doi: 10.1016/j.cmet.2023.02.014. Epub 2023 Mar 13. |
2022
| Kameda Y, Chuaychob S, Tanaka M, Liu Y, Okada R, Fujimoto K, Nakamura T, Yokokawa R. Three-dimensional tissue model in direct contact with an on-chip vascular bed enabled by removable membranes Lab Chip. 2022 Feb 1;22(3):641-651. doi: 10.1039/d1lc00751c. |
| Hirota K, Hirashima T, Horikawa K, Yasoda A, Matsuda M. C-type Natriuretic Peptide-induced PKA Activation Promotes Endochondral Bone Formation in Hypertrophic Chondrocytes Endocrinology. 2022 Mar 1;163(3):bqac005. doi: 10.1210/endocr/bqac005. |
| Ichise H, Tsukamoto S, Hirashima T, Konishi Y, Oki C, Tsukiji S, Iwano S, Miyawaki A, Sumiyama K, Terai K, Matsuda M. Functional visualization of NK cell-mediated killing of metastatic single tumor cells Elife. 2022 Feb 3;11:e76269. doi: 10.7554/eLife.76269. |
| Kaba S, Kawai Y, Tanigami Y, Ohnishi H, Kita T, Yoshimatsu M, Omori K, Kishimoto Y. Peroxisome Proliferator-Activated Receptor-γ Agonist Attenuates Vocal Fold Fibrosis in Rats via Regulation of Macrophage Activation Am J Pathol. 2022 May;192(5):771-782. doi: 10.1016/j.ajpath.2022.02.002. Epub 2022 Feb 19. |
| Takeda Y, Dai P. Capsaicin directly promotes adipocyte browning in the chemical compound-induced brown adipocytes converted from human dermal fibroblasts Sci Rep. 2022 Apr 22;12(1):6612. doi: 10.1038/s41598-022-10644-8. |
| Mori Y, Miyake M, Hosoda Y, Miki A, Takahashi A, Muraoka Y, Miyata M, Sato T, Tamura H, Ooto S, Yamada R, Yamashiro K, Nakamura M, Tajima A, Nagasaki M, Honda S, Tsujikawa A. Genome-wide Survival Analysis for Macular Neovascularization Development in Central Serous Chorioretinopathy Revealed Shared Genetic Susceptibility with Polypoidal Choroidal Vasculopathy Ophthalmology. 2022 Sep;129(9):1034-1042. doi: 10.1016/j.ophtha.2022.04.018. Epub 2022 Apr 29. |
| Tse KM, Vandenbon A, Cui X, Mino T, Uehata T, Yasuda K, Sato A, Tsujimura T, Hia F, Yoshinaga M, Kinoshita M, Okuno T, Takeuchi O. Enhancement of Regnase-1 expression with stem loop-targeting antisense oligonucleotides alleviates inflammatory diseases Sci Transl Med. 2022 May 11;14(644):eabo2137. doi: 10.1126/scitranslmed.abo2137. Epub 2022 May 11. |
| Asami J, Kimura KT, Fujita-Fujiharu Y, Ishida H, Zhang Z, Nomura Y, Liu K, Uemura T, Sato Y, Ono M, Yamamoto M, Noda T, Shigematsu H, Drew D, Iwata S, Shimizu T, Nomura N, Ohto U. Structure of the bile acid transporter and HBV receptor NTCP Nature. 2022 Jun;606(7916):1021-1026. doi: 10.1038/s41586-022-04845-4. Epub 2022 May 17. |
| Park JH, Iwamoto M, Yun JH, Uchikubo-Kamo T, Son D, Jin Z, Yoshida H, Ohki M, Ishimoto N, Mizutani K, Oshima M, Muramatsu M, Wakita T, Shirouzu M, Liu K, Uemura T, Nomura N, Iwata S, Watashi K, Tame JRH, Nishizawa T, Lee W, Park SY. Structural insights into the HBV receptor and bile acid transporter NTCP Nature. 2022 Jun;606(7916):1027-1031. doi: 10.1038/s41586-022-04857-0. Epub 2022 May 17. |
| Satoda Y, Noguchi T, Fujii T, Taniguchi A, Katoh Y, Nakayama K. BROMI/TBC1D32 together with CCRK/CDK20 and FAM149B1/JBTS36 contributes to intraflagellar transport turnaround involving ICK/CILK1 Mol Biol Cell. 2022 Aug 1;33(9):ar79. doi: 10.1091/mbc.E22-03-0089. Epub 2022 May 24. |
| Yamauchi I, Sakane Y, Okuno Y, Sugawa T, Hakata T, Fujita H, Okamoto K, Taura D, Yamashita T, Hirota K, Ueda Y, Fujii T, Yasoda A, Inagaki N. High-throughput Screening in Combination With a Cohort Study for Iodothyronine Deiodinases Endocrinology. 2022 Aug 1;163(8):bqac090. doi: 10.1210/endocr/bqac090. |
| Ishida Y, Tasaki K, Katoh Y, Nakayama K. Molecular basis underlying the ciliary defects caused by IFT52 variations found in skeletal ciliopathies Mol Biol Cell. 2022 Aug 1;33(9):ar83. doi: 10.1091/mbc.E22-05-0188. Epub 2022 Jun 15. |
| Ohgushi M, Taniyama N, Vandenbon A, Eiraku M. Delamination of trophoblast-like syncytia from the amniotic ectodermal analogue in human primed embryonic stem cell-based differentiation model Cell Rep. 2022 Jun 21;39(12):110973. doi: 10.1016/j.celrep.2022.110973. |
| Maeda R, Fujita J, Konishi Y, Kazuma Y, Yamazaki H, Anzai I, Watanabe T, Yamaguchi K, Kasai K, Nagata K, Yamaoka Y, Miyakawa K, Ryo A, Shirakawa K, Sato K, Makino F, Matsuura Y, Inoue T, Imura A, Namba K, Takaori-Kondo A. A panel of nanobodies recognizing conserved hidden clefts of all SARS-CoV-2 spike variants including Omicron Commun Biol. 2022 Jul 6;5(1):669. doi: 10.1038/s42003-022-03630-3. |
| Takeda Y, Dai P. Chronic Fatty Acid Depletion Induces Uncoupling Protein 1 (UCP1) Expression to Coordinate Mitochondrial Inducible Proton Leak in a Human-Brown-Adipocyte Model Cells. 2022 Jun 27;11(13):2038. doi: 10.3390/cells11132038. |
| Zhang Z, Nomura N, Muramoto Y, Ekimoto T, Uemura T, Liu K, Yui M, Kono N, Aoki J, Ikeguchi M, Noda T, Iwata S, Ohto U, Shimizu T. Structure of SARS-CoV-2 membrane protein essential for virus assembly Nat Commun. 2022 Aug 5;13(1):4399. doi: 10.1038/s41467-022-32019-3. |
| Koyauchi T, Niida H, Motegi A, Sakai S, Uchida C, Ohhata T, Iijima K, Yokoyama A, Suda T, Kitagawa M. Chromatin-remodeling factor BAZ1A/ACF1 targets UV damage sites in an MLL1-dependent manner to facilitate nucleotide excision repair Biochim Biophys Acta Mol Cell Res. 2022 Nov;1869(11):119332. doi: 10.1016/j.bbamcr.2022.119332. Epub 2022 Aug 5. |
| Yaku A, Inagaki T, Asano R, Okazawa M, Mori H, Sato A, Hia F, Masaki T, Manabe Y, Ishibashi T, Vandenbon A, Nakatsuka Y, Akaki K, Yoshinaga M, Uehata T, Mino T, Morita S, Ishibashi-Ueda H, Morinobu A, Tsujimura T, Ogo T, Nakaoka Y, Takeuchi O. Regnase-1 Prevents Pulmonary Arterial Hypertension Through mRNA Degradation of Interleukin-6 and Platelet-Derived Growth Factor in Alveolar Macrophages Circulation. 2022 Sep 27;146(13):1006-1022. doi: 10.1161/CIRCULATIONAHA.122.059435. Epub 2022 Aug 23. |
| Kawamura Y, Mogami H, Yasuda E, Takakura M, Matsuzaka Y, Ueda Y, Inohaya A, Kawasaki K, Chigusa Y, Mandai M, Kondoh E. Fetal macrophages assist in the repair of ruptured amnion through the induction of epithelial-mesenchymal transition Sci Signal. 2022 Sep 13;15(751):eabi5453. doi: 10.1126/scisignal.abi5453. Epub 2022 Sep 13. |
| Suno R, Sugita Y, Morimoto K, Takazaki H, Tsujimoto H, Hirose M, Suno-Ikeda C, Nomura N, Hino T, Inoue A, Iwasaki K, Kato T, Iwata S, Kobayashi T. Structural insights into the G protein selectivity revealed by the human EP3-G(i) signaling complex Cell Rep. 2022 Sep 13;40(11):111323. doi: 10.1016/j.celrep.2022.111323. |
| Ueda Y, Mogami H, Kawamura Y, Takakura M, Inohaya A, Yasuda E, Matsuzaka Y, Chigusa Y, Ito S, Mandai M, Kondoh E. Cervical MUC5B and MUC5AC are Barriers to Ascending Pathogens During Pregnancy J Clin Endocrinol Metab. 2022 Nov 23;107(11):3010-3021. doi: 10.1210/clinem/dgac545. |
| Fukushima Y, Sakamoto K, Matsuda M, Yoshikai Y, Yagita H, Kitamura D, Chihara M, Minato N, Hattori M. cis interaction of CD153 with TCR/CD3 is crucial for the pathogenic activation of senescence-associated T cells Cell Rep. 2022 Sep 20;40(12):111373. doi: 10.1016/j.celrep.2022.111373. |
| Hino N, Matsuda K, Jikko Y, Maryu G, Sakai K, Imamura R, Tsukiji S, Aoki K, Terai K, Hirashima T, Trepat X, Matsuda M. A feedback loop between lamellipodial extension and HGF-ERK signaling specifies leader cells during collective cell migration Dev Cell. 2022 Oct 10;57(19):2290-2304.e7. doi: 10.1016/j.devcel.2022.09.003. Epub 2022 Sep 28. |
| Abe M, Kamiyama T, Izumi Y, Qian Q, Yoshihashi Y, Degawa Y, Watanabe K, Hattori Y, Uemura T, Niwa R. Shortened lifespan induced by a high-glucose diet is associated with intestinal immune dysfunction in Drosophila sechellia J Exp Biol. 2022 Nov 1;225(21):jeb244423. doi: 10.1242/jeb.244423. Epub 2022 Oct 31. |
| Al-Habsi M, Chamoto K, Matsumoto K, Nomura N, Zhang B, Sugiura Y, Sonomura K, Maharani A, Nakajima Y, Wu Y, Nomura Y, Menzies R, Tajima M, Kitaoka K, Haku Y, Delghandi S, Yurimoto K, Matsuda F, Iwata S, Ogura T, Fagarasan S, Honjo T. Spermidine activates mitochondrial trifunctional protein and improves antitumor immunity in mice Science. 2022 Oct 28;378(6618):eabj3510. doi: 10.1126/science.abj3510. Epub 2022 Oct 28. |
| Yoshinaga M, Han K, Morgens DW, Horii T, Kobayashi R, Tsuruyama T, Hia F, Yasukura S, Kajiya A, Cai T, Cruz PHC, Vandenbon A, Suzuki Y, Kawahara Y, Hatada I, Bassik MC, Takeuchi O. The N(6)-methyladenosine methyltransferase METTL16 enables erythropoiesis through safeguarding genome integrity Nat Commun. 2022 Oct 28;13(1):6435. doi: 10.1038/s41467-022-34078-y. |
| Tamai K, Sakai K, Yamaki H, Moriguchi K, Igura K, Maehana S, Suezawa T, Takehara K, Hagiwara M, Hirai T, Gotoh S. iPSC-derived mesenchymal cells that support alveolar organoid development Cell Rep Methods. 2022 Sep 19;2(10):100314. doi: 10.1016/j.crmeth.2022.100314. eCollection 2022 Oct 24. |
| Nagata K, Utsumi D, Asaka MN, Maeda R, Shirakawa K, Kazuma Y, Nomura R, Horisawa Y, Yanagida Y, Kawai Y, Sato K, Yamaoka Y, Miyakawa K, Ryo A, Yasutomi Y, Imura A, Takaori-Kondo A. Intratracheal trimerized nanobody cocktail administration suppresses weight loss and prolongs survival of SARS-CoV-2 infected mice Commun Med (Lond). 2022 Nov 26;2(1):152. doi: 10.1038/s43856-022-00213-5. |
| Matsushima S, Ajiro M, Iida K, Chamoto K, Honjo T, Hagiwara M. Chemical induction of splice-neoantigens attenuates tumor growth in a preclinical model of colorectal cancer Sci Transl Med. 2022 Nov 30;14(673):eabn6056. doi: 10.1126/scitranslmed.abn6056. Epub 2022 Nov 30. |
| Murai S, Takakura K, Sumiyama K, Moriwaki K, Terai K, Komazawa-Sakon S, Seki T, Yamaguchi Y, Mikami T, Araki K, Ohmuraya M, Matsuda M, Nakano H. Generation of transgenic mice expressing a FRET biosensor, SMART, that responds to necroptosis Commun Biol. 2022 Dec 5;5(1):1331. doi: 10.1038/s42003-022-04300-0. |
| Someya Y, Iima M, Imai H, Yoshizawa A, Kataoka M, Isoda H, Le Bihan D, Nakamoto Y. Investigation of breast cancer microstructure and microvasculature from time-dependent DWI and CEST in correlation with histological biomarkers Sci Rep. 2022 Apr 20;12(1):6523. doi: 10.1038/s41598-022-10081-7. |
| Chong YK, Tartey S, Yoshikawa Y, Imami K, Li S, Yoshinaga M, Hirabayashi A, Liu G, Vandenbon A, Hia F, Uehata T, Mino T, Suzuki Y, Noda T, Ferrandon D, Standley DM, Ishihama Y, Takeuchi O. Cyclin J-CDK complexes limit innate immune responses by reducing proinflammatory changes in macrophage metabolism Sci Signal. 2022 Apr 12;15(729):eabm5011. doi: 10.1126/scisignal.abm5011. Epub 2022 Apr 12. |
| Kumagai K, Shimizu T, Takai A, Kakiuchi N, Takeuchi Y, Hirano T, Takeda H, Mizuguchi A, Teramura M, Ito T, Iguchi E, Nikaido M, Eso Y, Takahashi K, Ueda Y, Miyamoto S, Obama K, Ogawa S, Marusawa H, Seno H. Expansion of Gastric Intestinal Metaplasia with Copy Number Aberrations Contributes to Field Cancerization Cancer Res. 2022 May 3;82(9):1712-1723. doi: 10.1158/0008-5472.CAN-21-1523. |
| Kuno S, Fujita H, Tanaka YK, Ogra Y, Iwai K. Iron-induced NCOA4 condensation regulates ferritin fate and iron homeostasis EMBO Rep. 2022 May 4;23(5):e54278. doi: 10.15252/embr.202154278. Epub 2022 Mar 23. |
| Liu W, Ota M, Tabushi M, Takahashi Y, Takakura Y. Development of allergic rhinitis immunotherapy using antigen-loaded small extracellular vesicles J Control Release. 2022 May;345:433-442. doi: 10.1016/j.jconrel.2022.03.016. Epub 2022 Mar 14. |
| Fujita-Fujiharu Y, Sugita Y, Takamatsu Y, Houri K, Igarashi M, Muramoto Y, Nakano M, Tsunoda Y, Taniguchi I, Becker S, Noda T. Structural insight into Marburg virus nucleoprotein-RNA complex formation Nat Commun. 2022 Mar 4;13(1):1191. doi: 10.1038/s41467-022-28802-x. |
| Higashi Y, Ikeda S, Matsumoto K, Satoh S, Komatsu A, Sugiyama H, Tamanoi F. Tumor Accumulation of PIP-Based KRAS Inhibitor KR12 Evaluated by the Use of a Simple, Versatile Chicken Egg Tumor Model Cancers (Basel). 2022 Feb 14;14(4):951. doi: 10.3390/cancers14040951. |
| Hirota K, Ooka M, Shimizu N, Yamada K, Tsuda M, Ibrahim MA, Yamada S, Sasanuma H, Masutani M, Takeda S. XRCC1 counteracts poly(ADP ribose)polymerase (PARP) poisons, olaparib and talazoparib, and a clinical alkylating agent, temozolomide, by promoting the removal of trapped PARP1 from broken DNA Genes Cells. 2022 May;27(5):331-344. doi: 10.1111/gtc.12929. Epub 2022 Mar 1. |
| Matsuoka R, Fudim R, Jung S, Zhang C, Bazzone A, Chatzikyriakidou Y, Robinson CV, Nomura N, Iwata S, Landreh M, Orellana L, Beckstein O, Drew D. Structure, mechanism and lipid-mediated remodeling of the mammalian Na(+)/H(+) exchanger NHA2 Nat Struct Mol Biol. 2022 Feb;29(2):108-120. doi: 10.1038/s41594-022-00738-2. Epub 2022 Feb 16. |
| Kishi KE, Kim YS, Fukuda M, Inoue M, Kusakizako T, Wang PY, Ramakrishnan C, Byrne EFX, Thadhani E, Paggi JM, Matsui TE, Yamashita K, Nagata T, Konno M, Quirin S, Lo M, Benster T, Uemura T, Liu K, Shibata M, Nomura N, Iwata S, Nureki O, Dror RO, Inoue K, Deisseroth K, Kato HE. Structural basis for channel conduction in the pump-like channelrhodopsin ChRmine Cell. 2022 Feb 17;185(4):672-689.e23. doi: 10.1016/j.cell.2022.01.007. Epub 2022 Feb 2. |
| Inuki S, Tabuchi H, Matsuzaki C, Yonejima Y, Hisa K, Kimura I, Yamamoto K, Ohno H. Chemical Synthesis and Evaluation of Exopolysaccharide Fragments Produced by Leuconostoc mesenteroides Strain NTM048 Chem Pharm Bull (Tokyo). 2022;70(2):155-161. doi: 10.1248/cpb.c21-00919. |
| Tada T, Ohnishi H, Yamamoto N, Kuwata F, Hayashi Y, Okuyama H, Morino T, Kasai Y, Kojima H, Omori K. Transplantation of a human induced pluripotent stem cell-derived airway epithelial cell sheet into the middle ear of rats Regen Ther. 2022 Jan 14;19:77-87. doi: 10.1016/j.reth.2022.01.001. eCollection 2022 Mar. |
| Mukai Y, Horie M, Kojima S, Kawasaki J, Maeda K, Tomonaga K. An endogenous bornavirus-like nucleoprotein in miniopterid bats retains the RNA-binding properties of the original viral protein FEBS Lett. 2022 Feb;596(3):323-337. doi: 10.1002/1873-3468.14290. Epub 2022 Jan 30. |
| Takada N, Takasugi M, Nonaka Y, Kamiya T, Takemura K, Satoh J, Ito S, Fujimoto K, Uematsu S, Yoshida K, Morita T, Nakamura H, Uezumi A, Ohtani N. Galectin-3 promotes the adipogenic differentiation of PDGFRα+ cells and ectopic fat formation in regenerating muscle Development. 2022 Feb 1;149(3):dev199443. doi: 10.1242/dev.199443. Epub 2022 Feb 3. |
| Qiu H, Tsurumi Y, Katoh Y, Nakayama K. Combinations of deletion and missense variations of the dynein-2 DYNC2LI1 subunit found in skeletal ciliopathies cause ciliary defects Sci Rep. 2022 Jan 7;12(1):31. doi: 10.1038/s41598-021-03950-0. |
| Nanjo T, Matsugasako T, Maruo Y, Takemoto Y. Photocatalytic C-O Bond Cleavage of Alcohols Using Xanthate Salts Org Lett. 2022 Jan 14;24(1):359-363. doi: 10.1021/acs.orglett.1c04029. Epub 2021 Dec 27. |
| Zhou Z, Qiu H, Castro-Araya RF, Takei R, Nakayama K, Katoh Y. Impaired cooperation between IFT74/BBS22-IFT81 and IFT25-IFT27/BBS19 causes Bardet-Biedl syndrome Hum Mol Genet. 2022 May 19;31(10):1681-1693. doi: 10.1093/hmg/ddab354. |
| Kawamoto Y, Liu W, Yum JH, Park S, Sugiyama H, Takahashi Y, Takakura Y. Enhanced Immunostimulatory Activity of Covalent DNA Dendrons Chembiochem. 2022 Feb 16;23(4):e202100583. doi: 10.1002/cbic.202100583. Epub 2021 Dec 23. |
| Ito K, Kariya M, Yasui K, Takahashi Y, Takakura Y. Development of Hydrophobic Interaction-based DNA Supramolecules as Efficient Delivery Carriers of CpG DNA to Immune cells J Pharm Sci. 2022 Apr;111(4):1133-1141. doi: 10.1016/j.xphs.2021.11.027. Epub 2021 Dec 4. |
| Lin HH, Horie M, Tomonaga K. A comprehensive profiling of innate immune responses in Eptesicus bat cells Microbiol Immunol. 2022 Mar;66(3):97-112. doi: 10.1111/1348-0421.12952. Epub 2022 Jan 31. |
| Kuwata F, Ohnishi H, Yamamoto N, Takezawa T, Yamashita M, Okuyama H, Hayashi Y, Yoshimatsu M, Kitada Y, Tada T, Kobayashi M, Omori K. Transplantation of Human Induced Pluripotent Stem Cell-Derived Airway Cells on Vitrigel Membrane into Rat Nasal Cavity Tissue Eng Part A. 2022 Mar 30. doi: 10.1089/ten.TEA.2021.0071. Online ahead of print. |
| Sato Y, Oguchi A, Fukushima Y, Masuda K, Toriu N, Taniguchi K, Yoshikawa T, Cui X, Kondo M, Hosoi T, Komidori S, Shimizu Y, Fujita H, Jiang L, Kong Y, Yamanashi T, Seita J, Yamamoto T, Toyokuni S, Hamazaki Y, Hattori M, Yoshikai Y, Boor P, Floege J, Kawamoto H, Murakawa Y, Minato N, Yanagita M. CD153/CD30 signaling promotes age-dependent tertiary lymphoid tissue expansion and kidney injury J Clin Invest. 2022 Jan 18;132(2):e146071. doi: 10.1172/JCI146071. |
| Taichi Yumura, Dr. Takeshi Nanjo, Prof. Dr. Yoshiji Takemoto Boronic Acid-Mediated Photocatalysis Enables the Intramolecular Hydroacylation of Olefins Using Carboxylic Acids Eur. J. Org. Chem. 2022 Mar 23 doi:10.1002/ejoc.202200082 |
| Ahmad Luqman-Fatah, Yuzo Watanabe, Fuyuki Ishikawa, John V. Moran, Tomoichiro Miyoshi The interferon stimulated gene-encoded protein HELZ2 1 inhibits human LINE-1 retrotransposition and LINE-1 RNA-mediated type I interferon induction bioRxiv 2022 Mar 27 doi:10.1101/2022.03.26.485892 |
| Yousuke Yamaoka, Takuro Yamakawa, Kaito Tateishi, Kiyosei Takasu Total Synthesis of Cryptopleurine and its Analogues Synthesis 2022; 54(10): 2415-2422 doiI: 10.1055/a-1730-8628 |
| 藤田 陽子 フィロウイルスの粒子構造を視る 週刊医学のあゆみ, vol.280, No. 9, p933-937, 2022 |
2021
| Yamamoto R, Ohnishi H, Omori K, Yamamoto N. In silico analysis of inner ear development using public whole embryonic body single-cell RNA-sequencing data Dev Biol. 2021 Jan 1;469:160-171. doi: 10.1016/j.ydbio.2020.10.009. Epub 2020 Oct 22. |
| Suezawa T, Kanagaki S, Moriguchi K, Masui A, Nakao K, Toyomoto M, Tamai K, Mikawa R, Hirai T, Murakami K, Hagiwara M, Gotoh S. Disease modeling of pulmonary fibrosis using human pluripotent stem cell-derived alveolar organoids Stem Cell Reports. 2021 Dec 14;16(12):2973-2987. doi: 10.1016/j.stemcr.2021.10.015. Epub 2021 Nov 18. |
| Suezawa T, Kanagaki S, Korogi Y, Nakao K, Hirai T, Murakami K, Hagiwara M, Gotoh S. Modeling of lung phenotype of Hermansky-Pudlak syndrome type I using patient-specific iPSCs Respir Res. 2021 Nov 4;22(1):284. doi: 10.1186/s12931-021-01877-8. |
| Tawatari T, Takasu K, Takikawa H. 2-(Chlorodiisopropylsilyl)-6-(trimethylsilyl)phenyl triflate: a modified platform for intramolecular benzyne cycloadditions Chem Commun (Camb). 2021 Nov 9;57(89):11863-11866. doi: 10.1039/d1cc05264k. |
| Komatsu A, Matsumoto K, Yoshimatsu Y, Sin Y, Kubota A, Saito T, Mizumoto A, Ohashi S, Muto M, Noguchi R, Kondo T, Tamanoi F. The CAM Model for CIC-DUX4 Sarcoma and Its Potential Use for Precision Medicine Cells. 2021 Oct 1;10(10):2613. doi: 10.3390/cells10102613. |
| Noguchi T, Nakamura K, Satoda Y, Katoh Y, Nakayama K. CCRK/CDK20 regulates ciliary retrograde protein trafficking via interacting with BROMI/TBC1D32 PLoS One. 2021 Oct 8;16(10):e0258497. doi: 10.1371/journal.pone.0258497. eCollection 2021. |
| Komatsu H, Ikeuchi T, Tsuno H, Arichi N, Yasui K, Oishi S, Inuki S, Fukazawa A, Ohno H. Construction of Tricyclic Nitrogen Heterocycles by a Gold(I)-Catalyzed Cascade Cyclization of Allenynes and Application to Polycyclic π-Electron Systems Angew Chem Int Ed Engl. 2021 Dec 20;60(52):27019-27025. doi: 10.1002/anie.202111267. Epub 2021 Nov 22. |
| Takenaga T, Zhang Z, Muramoto Y, Fehling SK, Hirabayashi A, Takamatsu Y, Kajikawa J, Miyamoto S, Nakano M, Urata S, Groseth A, Strecker T, Noda T. CP100356 Hydrochloride, a P-Glycoprotein Inhibitor, Inhibits Lassa Virus Entry: Implication of a Candidate Pan-Mammarenavirus Entry Inhibitor Viruses. 2021 Sep 3;13(9):1763. doi: 10.3390/v13091763. |
| Murakami S, Nanjo T, Takemoto Y. Photocatalytic Activation of Elemental Sulfur Enables a Chemoselective Three-Component Thioesterification Org Lett. 2021 Oct 1;23(19):7650-7655. doi: 10.1021/acs.orglett.1c02904. Epub 2021 Sep 16. |
| Ghilarov D, Inaba-Inoue S, Stepien P, Qu F, Michalczyk E, Pakosz Z, Nomura N, Ogasawara S, Walker GC, Rebuffat S, Iwata S, Heddle JG, Beis K. Molecular mechanism of SbmA, a promiscuous transporter exploited by antimicrobial peptides Sci Adv. 2021 Sep 10;7(37):eabj5363. doi: 10.1126/sciadv.abj5363. Epub 2021 Sep 8. |
| Kinouchi H, Sugimoto K, Yamaoka Y, Takikawa H, Takasu K. Oxidative β-Cleavage of Fused Cyclobutanols Leading to Hydrofuran-Fused Polycyclic Aromatic Compounds J Org Chem. 2021 Sep 17;86(18):12615-12622. doi: 10.1021/acs.joc.1c01108. Epub 2021 Sep 2. |
| Fujisawa S, Qiu H, Nozaki S, Chiba S, Katoh Y, Nakayama K. ARL3 and ARL13B GTPases participate in distinct steps of INPP5E targeting to the ciliary membrane Biol Open. 2021 Sep 15;10(9):bio058843. doi: 10.1242/bio.058843. Epub 2021 Sep 28. |
| Yoshinari Y, Kosakamoto H, Kamiyama T, Hoshino R, Matsuoka R, Kondo S, Tanimoto H, Nakamura A, Obata F, Niwa R. The sugar-responsive enteroendocrine neuropeptide F regulates lipid metabolism through glucagon-like and insulin-like hormones in Drosophila melanogaster Nat Commun. 2021 Aug 10;12(1):4818. doi: 10.1038/s41467-021-25146-w. |
| Neville SL, Sjöhamn J, Watts JA, MacDermott-Opeskin H, Fairweather SJ, Ganio K, Carey Hulyer A, McGrath AP, Hayes AJ, Malcolm TR, Davies MR, Nomura N, Iwata S, O’Mara ML, Maher MJ, McDevitt CA. The structural basis of bacterial manganese import Sci Adv. 2021 Aug 6;7(32):eabg3980. doi: 10.1126/sciadv.abg3980. Print 2021 Aug. |
| Okamoto HH, Miyauchi H, Inoue A, Raimondi F, Tsujimoto H, Kusakizako T, Shihoya W, Yamashita K, Suno R, Nomura N, Kobayashi T, Iwata S, Nishizawa T, Nureki O. Cryo-EM structure of the human MT(1)-G(i) signaling complex Nat Struct Mol Biol. 2021 Aug;28(8):694-701. doi: 10.1038/s41594-021-00634-1. Epub 2021 Aug 5. |
| Iwai S, Ikeda HO, Mera H, Nishitani K, Saito M, Tsujikawa A, Kakizuka A. KUS121 attenuates the progression of monosodium iodoacetate-induced osteoarthritis in rats Sci Rep. 2021 Aug 2;11(1):15651. doi: 10.1038/s41598-021-95173-6. |
| Garcia BCB, Horie M, Kojima S, Makino A, Tomonaga K. BUD23-TRMT112 interacts with the L protein of Borna disease virus and mediates the chromosomal tethering of viral ribonucleoproteins Microbiol Immunol. 2021 Nov;65(11):492-504. doi: 10.1111/1348-0421.12934. Epub 2021 Sep 17. |
| Uehata T, Takeuchi O. Post-transcriptional regulation of immunological responses by Regnase-1-related RNases Int Immunol. 2021 Nov 25;33(12):859-865. doi: 10.1093/intimm/dxab048. |
| Ajiro M, Awaya T, Kim YJ, Iida K, Denawa M, Tanaka N, Kurosawa R, Matsushima S, Shibata S, Sakamoto T, Studer L, Krainer AR, Hagiwara M. Therapeutic manipulation of IKBKAP mis-splicing with a small molecule to cure familial dysautonomia Nat Commun. 2021 Jul 23;12(1):4507. doi: 10.1038/s41467-021-24705-5. |
| Nakano M, Sugita Y, Kodera N, Miyamoto S, Muramoto Y, Wolf M, Noda T. Ultrastructure of influenza virus ribonucleoprotein complexes during viral RNA synthesis Commun Biol. 2021 Jul 9;4(1):858. doi: 10.1038/s42003-021-02388-4. |
| Miyata Y, Nishida E. Protein quality control of DYRK family protein kinases by the Hsp90-Cdc37 molecular chaperone Biochim Biophys Acta Mol Cell Res. 2021 Sep;1868(10):119081. doi: 10.1016/j.bbamcr.2021.119081. Epub 2021 Jun 18. |
| Greiner LC, Inuki S, Arichi N, Oishi S, Suzuki R, Iwai T, Sawamura M, Hashmi ASK, Ohno H. Access to Indole-Fused Benzannulated Medium-Sized Rings through a Gold(I)-Catalyzed Cascade Cyclization of Azido-Alkynes Chemistry. 2021 Sep 9;27(51):12992-12997. doi: 10.1002/chem.202101824. Epub 2021 Jul 9. |
| Maeda S, Shiimura Y, Asada H, Hirata K, Luo F, Nango E, Tanaka N, Toyomoto M, Inoue A, Aoki J, Iwata S, Hagiwara M. Endogenous agonist-bound S1PR3 structure reveals determinants of G protein-subtype bias Sci Adv. 2021 Jun 9;7(24):eabf5325. doi: 10.1126/sciadv.abf5325. Print 2021 Jun. |
| Fujino K, Horie M, Kojima S, Shimizu S, Nabekura A, Kobayashi H, Makino A, Honda T, Tomonaga K. A Human Endogenous Bornavirus-Like Nucleoprotein Encodes a Mitochondrial Protein Associated with Cell Viability J Virol. 2021 Jun 24;95(14):e0203020. doi: 10.1128/JVI.02030-20. Epub 2021 Jun 24. |
| Inoue M, Enomoto M, Yoshimura M, Mizowaki T. Pharmacological inhibition of sodium-calcium exchange activates NADPH oxidase and induces infection-independent NETotic cell death Redox Biol. 2021 Jul;43:101983. doi: 10.1016/j.redox.2021.101983. Epub 2021 Apr 26. |
| Jin F, Sun M, Fujii T, Yamada Y, Wang J, Maturana AD, Wada M, Su S, Ma J, Takeda H, Kusakizako T, Tomita A, Nakada-Nakura Y, Liu K, Uemura T, Nomura Y, Nomura N, Ito K, Nureki O, Namba K, Iwata S, Yu Y, Hattori M. The structure of MgtE in the absence of magnesium provides new insights into channel gating PLoS Biol. 2021 Apr 27;19(4):e3001231. doi: 10.1371/journal.pbio.3001231. eCollection 2021 Apr. |
| Egawa G, Egawa K, Kabashima K. Is breakthrough chickenpox caused by different genotypes of Varicella zoster virus? Pediatr Int. 2021 Apr;63(4):478-480. doi: 10.1111/ped.14440. Epub 2021 Apr 3. |
| Tagawa M, Ikeda HO, Inoue Y, Iwai S, Iida Y, Hata M, Asaka I, Tsujikawa A. Deterioration of phagocytosis in induced pluripotent stem cell-derived retinal pigment epithelial cells established from patients with retinitis pigmentosa carrying Mer tyrosine kinase mutations Exp Eye Res. 2021 Apr;205:108503. doi: 10.1016/j.exer.2021.108503. Epub 2021 Feb 17. |
| Yoshimatsu M, Ohnishi H, Zhao C, Hayashi Y, Kuwata F, Kaba S, Okuyama H, Kawai Y, Hiwatashi N, Kishimoto Y, Sakamoto T, Ikeya M, Omori K. In vivo regeneration of rat laryngeal cartilage with mesenchymal stem cells derived from human induced pluripotent stem cells via neural crest cells Stem Cell Res. 2021 Apr;52:102233. doi: 10.1016/j.scr.2021.102233. Epub 2021 Feb 11. |
| Toyomoto M, Inoue A, Iida K, Denawa M, Kii I, Ngako Kadji FM, Kishi T, Im D, Shimamura T, Onogi H, Yoshida S, Iwata S, Aoki J, Hosoya T, Hagiwara M. S1PR3-G(12)-biased agonist ALESIA targets cancer metabolism and promotes glucose starvation Cell Chem Biol. 2021 Aug 19;28(8):1132-1144.e9. doi: 10.1016/j.chembiol.2021.01.004. Epub 2021 Feb 8. |
| Moribe F, Nishikori M, Takashima T, Taniyama D, Onishi N, Arima H, Sasanuma H, Akagawa R, Elloumi F, Takeda S, Pommier Y, Morii E, Takaori-Kondo A, Murai J. Epigenetic suppression of SLFN11 in germinal center B-cells during B-cell development PLoS One. 2021 Jan 29;16(1):e0237554. doi: 10.1371/journal.pone.0237554. eCollection 2021. |
| Mu A, Hira A, Niwa A, Osawa M, Yoshida K, Mori M, Okamoto Y, Inoue K, Kondo K, Kanemaki MT, Matsuda T, Ito E, Kojima S, Nakahata T, Ogawa S, Tanaka K, Matsuo K, Saito MK, Takata M. Analysis of disease model iPSCs derived from patients with a novel Fanconi anemia-like IBMFS ADH5/ALDH2 deficiency Blood. 2021 Apr 15;137(15):2021-2032. doi: 10.1182/blood.2020009111. |
| Mu A, Hira A, Niwa A, Osawa M, Yoshida K, Mori M, Okamoto Y, Inoue K, Kondo K, Kanemaki MT, Matsuda T, Ito E, Kojima S, Nakahata T, Ogawa S, Tanaka K, Matsuo K, Saito MK, Takata M. Analysis of disease model iPSCs derived from patients with a novel Fanconi anemia-like IBMFS ADH5/ALDH2 deficiency Blood. 2021 Apr 15;137(15):2021-2032. doi: 10.1182/blood.2020009111. |
| Kanagaki S, Suezawa T, Moriguchi K, Nakao K, Toyomoto M, Yamamoto Y, Murakami K, Hagiwara M, Gotoh S. Hydroxypropyl Cyclodextrin Improves Amiodarone-induced Aberrant Lipid Homeostasis of Alveolar Cells Am J Respir Cell Mol Biol. 2021 Apr;64(4):504-514. doi: 10.1165/rcmb.2020-0119OC. |
| Yin X, Riva L, Pu Y, Martin-Sancho L, Kanamune J, Yamamoto Y, Sakai K, Gotoh S, Miorin L, De Jesus PD, Yang CC, Herbert KM, Yoh S, Hultquist JF, García-Sastre A, Chanda SK. MDA5 Governs the Innate Immune Response to SARS-CoV-2 in Lung Epithelial Cells Cell Rep. 2021 Jan 12;34(2):108628. doi: 10.1016/j.celrep.2020.108628. |
| Maruno T, Fukuda A, Goto N, Tsuda M, Ikuta K, Hiramatsu Y, Ogawa S, Nakanishi Y, Yamaga Y, Yoshioka T, Takaori K, Uemoto S, Saur D, Chiba T, Seno H. Visualization of stem cell activity in pancreatic cancer expansion by direct lineage tracing with live imaging Elife. 2021 Jan 4;10:e55117. doi: 10.7554/eLife.55117. |
| Qiu H, Fujisawa S, Nozaki S, Katoh Y, Nakayama K. Interaction of INPP5E with ARL13B is essential for its ciliary membrane retention but dispensable for its ciliary entry Biol Open. 2021 Jan 25;10(1):bio057653. doi: 10.1242/bio.057653. |
| Suzuki R, Murata MM, Manguso N, Watanabe T, Mouakkad-Montoya L, Igari F, Rahman MM, Qu Y, Cui X, Giuliano AE, Takeda S, Tanaka H. The fragility of a structurally diverse duplication block triggers recurrent genomic amplification Nucleic Acids Res. 2021 Jan 11;49(1):244-256. doi: 10.1093/nar/gkaa1136. |
| Nojima S, Fujita Y, Kimura KT, Nomura N, Suno R, Morimoto K, Yamamoto M, Noda T, Iwata S, Shigematsu H, Kobayashi T. Cryo-EM Structure of the Prostaglandin E Receptor EP4 Coupled to G Protein Structure. 2021 Mar 4;29(3):252-260.e6. doi: 10.1016/j.str.2020.11.007. Epub 2020 Dec 1. |
| Kanagaki S, Ikeo S, Suezawa T, Yamamoto Y, Seki M, Hirai T, Hagiwara M, Suzuki Y, Gotoh S. Directed induction of alveolar type I cells derived from pluripotent stem cells via Wnt signaling inhibition Stem Cells. 2021 Feb;39(2):156-169. doi: 10.1002/stem.3302. Epub 2020 Nov 26. |
| Kato T, Harada N, Ikeguchi-Ogura E, Sankoda A, Hatoko T, Lu X, Yasuda T, Yamane S, Inagaki N. Gene expression of nutrient-sensing molecules in I cells of CCK reporter male mice J Mol Endocrinol. 2021 Jan;66(1):11-22. doi: 10.1530/JME-20-0134. |
| Hirose Y, Hashiya K, Bando T, Sugiyama H. Evaluation of the DNA Alkylation Properties of a Chlorambucil-Conjugated Cyclic Pyrrole-Imidazole Polyamide Chemistry. 2021 Feb 5;27(8):2782-2788. doi: 10.1002/chem.202004421. Epub 2021 Jan 14. |
| Matsuoka T, Motozono C, Hattori A, Kakeya H, Yamasaki S, Oishi S, Ohno H, Inuki S. The effects of 5-OP-RU stereochemistry on its stability and MAIT-MR1 axis Chembiochem. 2021 Feb 15;22(4):672-678. doi: 10.1002/cbic.202000466. Epub 2020 Nov 16. |
| Ryotaro Yagita, Prof. Dr. Kazuhiro Irie, Dr. Chihiro Tsukano Studies Toward the Total Synthesis of Schinortriterpenoids: Diastereoselective Synthesis of the Left-Hand Fragment Eur. J. Org. Chem. 2021 May 07 doi:10.1002/ejoc.202100510 |
| Ayumi Uchino, Dr. Chihiro Tsukano, Prof. Dr. Tsuneo Imamoto, Prof. Dr. Kazuhiro Irie Synthesis of Alkyl Bridged-Tris-α-Amino Acids as C3- Symmetric and Linear Linkers Eur. J. Org. Chem. 2021 Jan 25 doi:10.1002/ejoc.202001592 |
| Kohta Yamasaki, Akiho Yamauchi, Dr. Tsubasa Inokuma, Yasunori Miyakawa, Dr. Yinli Wang, Dr. Raphaël Oriez, Dr. Yousuke Yamaoka, Prof. Dr. Kiyosei Takasu, Prof. Dr. Naonobu Tanaka, Prof. Dr. Yoshiki Kashiwada, Prof. Dr. Ken-ichi Yamada Mechanistic Support for Intramolecular Migrative Cyclization of Propargyl Sulfones Provided by Catalytic Asymmetric Induction with a Chiral Counter Cation Strategy Asian J. Org. Chem. 2021 Apr 16 doi:10.1002/ajoc.202100274 |
| Ken-ichi Yamada, Shinichi Fujiwara , Tsubasa Inokuma, Masayuki Sugano, Yousuke Yamaoka, Kiyosei Takasu The rationale for stereoinduction in conjugate addition to alkylidenemalonates bearing a menthol-derived chiral auxiliary Tetrahedron 2021 Jul 2 doi:10.1016/j.tet.2021.132220 |
| Hisashi Hashimoto, Dr. Yoshihiro Ueda, Kiyosei Takasu, Prof. Takeo Kawabata Catalytic Substrate-Selective Silylation of Primary Alcohols via Remote Functional-Group Discrimination Angew. Chem. Int. Ed. 2021 Dec 23 doi:10.1002/ange.202114118 |
| 武長徹 ラッサウイルスの細胞侵入阻害薬の開発 生体の科学 72巻4号 （2021年8月） |
2020
| Rahman MM, Mohiuddin M, Shamima Keka I, Yamada K, Tsuda M, Sasanuma H, Andreani J, Guerois R, Borde V, Charbonnier JB, Takeda S. Genetic evidence for the involvement of mismatch repair proteins, PMS2 and MLH3, in a late step of homologous recombination J Biol Chem. 2020 Dec 18;295(51):17460-17475. doi: 10.1074/jbc.RA120.013521. |
| Takeishi A, Kogashi H, Odagiri M, Sasanuma H, Takeda S, Yasui M, Honma M, Suzuki T, Kamiya H, Sugasawa K, Ura K, Sassa A. Tyrosyl-DNA phosphodiesterases are involved in mutagenic events at a ribonucleotide embedded into DNA in human cells PLoS One. 2020 Dec 31;15(12):e0244790. doi: 10.1371/journal.pone.0244790. eCollection 2020. |
| Matsunaga M, Kita T, Yamamoto R, Yamamoto N, Okano T, Omori K, Sakamoto S, Nakagawa T. Initiation of Supporting Cell Activation for Hair Cell Regeneration in the Avian Auditory Epithelium: An Explant Culture Model Front Cell Neurosci. 2020 Nov 12;14:583994. doi: 10.3389/fncel.2020.583994. eCollection 2020. |
| Noura M, Morita K, Kiyose H, Matsuo H, Nishinaka-Arai Y, Kurokawa M, Kamikubo Y, Adachi S. Pivotal role of DPYSL2A in KLF4-mediated monocytic differentiation of acute myeloid leukemia cells Sci Rep. 2020 Nov 20;10(1):20245. doi: 10.1038/s41598-020-76951-0. |
| Shiimura Y, Horita S, Hamamoto A, Asada H, Hirata K, Tanaka M, Mori K, Uemura T, Kobayashi T, Iwata S, Kojima M. Structure of an antagonist-bound ghrelin receptor reveals possible ghrelin recognition mode Nat Commun. 2020 Aug 19;11(1):4160. doi: 10.1038/s41467-020-17554-1. |
| Okazaki M, Kobayashi T, Chiba S, Takei R, Liang L, Nakayama K, Katoh Y. Formation of the B9-domain protein complex MKS1-B9D2-B9D1 is essential as a diffusion barrier for ciliary membrane proteins Mol Biol Cell. 2020 Sep 15;31(20):2259-2268. doi: 10.1091/mbc.E20-03-0208. Epub 2020 Jul 29. |
| Morita D, Iwashita C, Mizutani T, Mori N, Mikami B, Sugita M. Crystal structure of the ternary complex of TCR, MHC class I and lipopeptides Int Immunol. 2020 Nov 23;32(12):805-810. doi: 10.1093/intimm/dxaa050. |
| Maeda R, Ito S, Hashiya K, Bando T, Sugiyama H. DNA Alkylation of the RUNX-Binding Sequence by CBI-PI Polyamide Conjugates* Chemistry. 2020 Nov 17;26(64):14639-14644. doi: 10.1002/chem.202002166. Epub 2020 Oct 6. |
| Nakano T, Shoulkamy MI, Tsuda M, Sasanuma H, Hirota K, Takata M, Masunaga SI, Takeda S, Ide H, Bessho T, Tano K. Participation of TDP1 in the repair of formaldehyde-induced DNA-protein cross-links in chicken DT40 cells PLoS One. 2020 Jun 26;15(6):e0234859. doi: 10.1371/journal.pone.0234859. eCollection 2020. |
| Nyuzuki H, Ito S, Nagasaki K, Nitta Y, Matsui N, Saitoh A, Matsui H. Degeneration of dopaminergic neurons and impaired intracellular trafficking in Atp13a2 deficient zebrafish IBRO Rep. 2020 Jun 1;9:1-8. doi: 10.1016/j.ibror.2020.05.002. eCollection 2020 Dec. |
| Saha LK, Wakasugi M, Akter S, Prasad R, Wilson SH, Shimizu N, Sasanuma H, Huang SN, Agama K, Pommier Y, Matsunaga T, Hirota K, Iwai S, Nakazawa Y, Ogi T, Takeda S. Topoisomerase I-driven repair of UV-induced damage in NER-deficient cells Proc Natl Acad Sci U S A. 2020 Jun 23;117(25):14412-14420. doi: 10.1073/pnas.1920165117. Epub 2020 Jun 8. |
| Nakai S, Oyabu M, Hatazawa Y, Akashi S, Kitamura T, Miura S, Kamei Y. FOXO1 suppresses PGC-1β gene expression in skeletal muscles FEBS Open Bio. 2020 Jul;10(7):1373-1388. doi: 10.1002/2211-5463.12898. |
| Zou Y, Ito S, Yoshino F, Suzuki Y, Zhao L, Komatsu N. Polyglycerol Grafting Shields Nanoparticles from Protein Corona Formation to Avoid Macrophage Uptake ACS Nano. 2020 Jun 23;14(6):7216-7226. doi: 10.1021/acsnano.0c02289. Epub 2020 May 20. |
| Nishimura F, Mogami H, Moriuchi K, Chigusa Y, Mandai M, Kondoh E. Mechanisms of thrombin-Induced myometrial contractions: Potential targets of progesterone PLoS One. 2020 May 4;15(5):e0231944. doi: 10.1371/journal.pone.0231944. eCollection 2020. |
| Akagawa R, Trinh HT, Saha LK, Tsuda M, Hirota K, Yamada S, Shibata A, Kanemaki MT, Nakada S, Takeda S, Sasanuma H. UBC13-Mediated Ubiquitin Signaling Promotes Removal of Blocking Adducts from DNA Double-Strand Breaks iScience. 2020 Apr 24;23(4):101027. doi: 10.1016/j.isci.2020.101027. Epub 2020 Mar 31. |
| Al Mahmud MR, Ishii K, Bernal-Lozano C, Delgado-Sainz I, Toi M, Akamatsu S, Fukumoto M, Watanabe M, Takeda S, Cortés-Ledesma F, Sasanuma H. TDP2 suppresses genomic instability induced by androgens in the epithelial cells of prostate glands Genes Cells. 2020 Jul;25(7):450-465. doi: 10.1111/gtc.12770. Epub 2020 May 5. |
| Shima Y, Morita D, Mizutani T, Mori N, Mikami B, Sugita M. Crystal structures of lysophospholipid-bound MHC class I molecules J Biol Chem. 2020 May 15;295(20):6983-6991. doi: 10.1074/jbc.RA119.011932. Epub 2020 Apr 8. |
| Ibrahim MA, Yasui M, Saha LK, Sasanuma H, Honma M, Takeda S. Enhancing the sensitivity of the thymidine kinase assay by using DNA repair-deficient human TK6 cells Environ Mol Mutagen. 2020 Jul;61(6):602-610. doi: 10.1002/em.22371. Epub 2020 Apr 15. |
| Hasegawa T, Ikeda HO, Gotoh N, Iida K, Iwai S, Nakano N, Kakizuka A, Tsujikawa A. Effect of VCP modulators on gene expression profiles of retinal ganglion cells in an acute injury mouse model Sci Rep. 2020 Mar 6;10(1):4251. doi: 10.1038/s41598-020-61160-6. |
| Itou J, Takahashi R, Sasanuma H, Tsuda M, Morimoto S, Matsumoto Y, Ishii T, Sato F, Takeda S, Toi M. Estrogen Induces Mammary Ductal Dysplasia via the Upregulation of Myc Expression in a DNA-Repair-Deficient Condition iScience. 2020 Feb 21;23(2):100821. doi: 10.1016/j.isci.2020.100821. Epub 2020 Jan 9. |
| de Las Rivas M, Paul Daniel EJ, Narimatsu Y, Compañón I, Kato K, Hermosilla P, Thureau A, Ceballos-Laita L, Coelho H, Bernadó P, Marcelo F, Hansen L, Maeda R, Lostao A, Corzana F, Clausen H, Gerken TA, Hurtado-Guerrero R. Molecular basis for fibroblast growth factor 23 O-glycosylation by GalNAc-T3 Nat Chem Biol. 2020 Mar;16(3):351-360. doi: 10.1038/s41589-019-0444-x. Epub 2020 Jan 13. |
| Asada H, Inoue A, Ngako Kadji FM, Hirata K, Shiimura Y, Im D, Shimamura T, Nomura N, Iwanari H, Hamakubo T, Kusano-Arai O, Hisano H, Uemura T, Suno C, Aoki J, Iwata S. The Crystal Structure of Angiotensin II Type 2 Receptor with Endogenous Peptide Hormone Structure. 2020 Apr 7;28(4):418-425.e4. doi: 10.1016/j.str.2019.12.003. Epub 2019 Dec 30. |
| Malinee M, Kumar A, Hidaka T, Horie M, Hasegawa K, Pandian GN, Sugiyama H. Targeted suppression of metastasis regulatory transcription factor SOX2 in various cancer cell lines using a sequence-specific designer pyrrole-imidazole polyamide Bioorg Med Chem. 2020 Feb 1;28(3):115248. doi: 10.1016/j.bmc.2019.115248. Epub 2019 Dec 6. |
| Abe H, Satoh J, Shirasaka Y, Kogure A, Kato H, Ito S, Fujita T. Priming Phosphorylation of TANK-Binding Kinase 1 by IκB Kinase β Is Essential in Toll-Like Receptor 3/4 Signaling Mol Cell Biol. 2020 Feb 12;40(5):e00509-19. doi: 10.1128/MCB.00509-19. Print 2020 Feb 12. |
| Egawa G, Egawa K, Kabashima K. Case of chickenpox in which varicella zoster virus genotype E was identified for the first time in Japan J Dermatol. 2020 Jan;47(1):54-57. doi: 10.1111/1346-8138.15153. Epub 2019 Nov 19. |
2019
| Hirata CL, Ito S, Masutani H. Dataset on the formation of Thioredoxin interacting protein (Txnip) containing redox sensitive high molecular weight nucleoprotein complexes Data Brief. 2019 Nov 29;28:104893. doi: 10.1016/j.dib.2019.104893. eCollection 2020 Feb. |
| Nomura N, Nomura Y, Sato Y, Iwata S. Crystallographic approaches to study the interaction modes of PD-1- and CTLA-4-blocking antibodies Methods Enzymol. 2019;629:383-399. doi: 10.1016/bs.mie.2019.10.008. Epub 2019 Oct 29. |
| Morimoto S, Tsuda M, Bunch H, Sasanuma H, Austin C, Takeda S. Type II DNA Topoisomerases Cause Spontaneous Double-Strand Breaks in Genomic DNA Genes (Basel). 2019 Oct 30;10(11):868. doi: 10.3390/genes10110868. |
| Hirata CL, Ito S, Masutani H. Thioredoxin interacting protein (Txnip) forms redox sensitive high molecular weight nucleoprotein complexes Arch Biochem Biophys. 2019 Nov 30;677:108159. doi: 10.1016/j.abb.2019.108159. Epub 2019 Oct 24. |
| Sassa A, Tada H, Takeishi A, Harada K, Suzuki M, Tsuda M, Sasanuma H, Takeda S, Sugasawa K, Yasui M, Honma M, Ura K. Processing of a single ribonucleotide embedded into DNA by human nucleotide excision repair and DNA polymerase η Sci Rep. 2019 Sep 26;9(1):13910. doi: 10.1038/s41598-019-50421-8. |
| Mukai Y, Tomita Y, Kryukov K, Nakagawa S, Ozawa M, Matsui T, Tomonaga K, Imanishi T, Kawaoka Y, Watanabe T, Horie M. Identification of a distinct lineage of aviadenovirus from crane feces Virus Genes. 2019 Dec;55(6):815-824. doi: 10.1007/s11262-019-01703-w. Epub 2019 Sep 23. |
| Kinjo T, Terai K, Horita S, Nomura N, Sumiyama K, Togashi K, Iwata S, Matsuda M. FRET-assisted photoactivation of flavoproteins for in vivo two-photon optogenetics Nat Methods. 2019 Oct;16(10):1029-1036. doi: 10.1038/s41592-019-0541-5. Epub 2019 Sep 9. |
| Watanabe K, Kanaoka Y, Mizutani S, Uchiyama H, Yajima S, Watada M, Uemura T, Hattori Y. Interspecies Comparative Analyses Reveal Distinct Carbohydrate-Responsive Systems among Drosophila Species Cell Rep. 2019 Sep 3;28(10):2594-2607.e7. doi: 10.1016/j.celrep.2019.08.030. |
| Nozaki S, Castro Araya RF, Katoh Y, Nakayama K. Requirement of IFT-B-BBSome complex interaction in export of GPR161 from cilia Biol Open. 2019 Sep 17;8(9):bio043786. doi: 10.1242/bio.043786. |
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